Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| T47DKBLUC | Unknown | Unknown | TCS 2312 | CHK1 | CHK | 0.0533 | uM | 12608.152 | 1.0088 | 1.0154 | 1.1477 | |
| T47DKBLUC | Unknown | Unknown | TCS 2312 | CHK1 | CHK | 0.267 | uM | 12608.152 | 1.0253 | 1.0441 | 1.1477 | |
| T47DKBLUC | Unknown | Unknown | TCS 2312 | CHK1 | CHK | 1.33 | uM | 12608.152 | 0.9932 | 0.9881 | 1.1477 | |
| T47DKBLUC | Unknown | Unknown | TCS 2312 | CHK1 | CHK | 6.67 | uM | 12608.152 | 0.4594 | 0.0155 | 1.1477 | |
| T47DKBLUC | Unknown | Unknown | TCS 2312 | CHK1 | CHK | 33.3 | uM | 12608.152 | 0.4765 | 0.0484 | 1.1477 | |
| UACC-812 | HER2amp | Luminal | TCS 2312 | CHK1 | CHK | 0.0000853 | uM | 10580.14 | 0.9381 | 0.8579 | 0.8679 | |
| UACC-812 | HER2amp | Luminal | TCS 2312 | CHK1 | CHK | 0.000427 | uM | 10580.14 | 0.9092 | 0.7923 | 0.8679 | |
| UACC-812 | HER2amp | Luminal | TCS 2312 | CHK1 | CHK | 0.00213 | uM | 10580.14 | 0.9642 | 0.9178 | 0.8679 | |
| UACC-812 | HER2amp | Luminal | TCS 2312 | CHK1 | CHK | 0.0107 | uM | 10580.14 | 0.9893 | 0.9754 | 0.8679 | |
| UACC-812 | HER2amp | Luminal | TCS 2312 | CHK1 | CHK | 0.0533 | uM | 10580.14 | 0.9455 | 0.8749 | 0.8679 | |
| UACC-812 | HER2amp | Luminal | TCS 2312 | CHK1 | CHK | 0.267 | uM | 10580.14 | 0.9276 | 0.8341 | 0.8679 | |
| UACC-812 | HER2amp | Luminal | TCS 2312 | CHK1 | CHK | 1.33 | uM | 10580.14 | 0.7180 | 0.3654 | 0.8679 | |
| UACC-812 | HER2amp | Luminal | TCS 2312 | CHK1 | CHK | 6.67 | uM | 10580.14 | 0.3342 | -0.4342 | 0.8679 | |
| UACC-812 | HER2amp | Luminal | TCS 2312 | CHK1 | CHK | 33.3 | uM | 10580.14 | 0.2831 | -0.5328 | 0.8679 | |
| UACC-812 | HER2amp | Luminal | TCS 2312 | CHK1 | CHK | 0.0000853 | uM | 10754.152 | 0.9751 | 0.9533 | 1.0670 | |
| UACC-812 | HER2amp | Luminal | TCS 2312 | CHK1 | CHK | 0.000427 | uM | 10754.152 | 0.9534 | 0.9124 | 1.0670 | |
| UACC-812 | HER2amp | Luminal | TCS 2312 | CHK1 | CHK | 0.00213 | uM | 10754.152 | 0.9736 | 0.9504 | 1.0670 | |
| UACC-812 | HER2amp | Luminal | TCS 2312 | CHK1 | CHK | 0.0107 | uM | 10754.152 | 0.9368 | 0.8812 | 1.0670 | |
| UACC-812 | HER2amp | Luminal | TCS 2312 | CHK1 | CHK | 0.0533 | uM | 10754.152 | 1.0093 | 1.0175 | 1.0670 | |
| UACC-812 | HER2amp | Luminal | TCS 2312 | CHK1 | CHK | 0.267 | uM | 10754.152 | 0.9471 | 0.9007 | 1.0670 | |
| UACC-812 | HER2amp | Luminal | TCS 2312 | CHK1 | CHK | 1.33 | uM | 10754.152 | 0.6009 | 0.2409 | 1.0670 | |
| UACC-812 | HER2amp | Luminal | TCS 2312 | CHK1 | CHK | 6.67 | uM | 10754.152 | 0.3542 | -0.2439 | 1.0670 | |
| UACC-812 | HER2amp | Luminal | TCS 2312 | CHK1 | CHK | 33.3 | uM | 10754.152 | 0.2527 | -0.4491 | 1.0670 | |
| UACC-812 | HER2amp | Luminal | TCS 2312 | CHK1 | CHK | 0.0000853 | uM | 11938.159 | 1.0097 | 1.0461 | 0.4219 | |
| UACC-812 | HER2amp | Luminal | TCS 2312 | CHK1 | CHK | 0.000427 | uM | 11938.159 | 0.9936 | 0.9696 | 0.4219 |