Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC38 | TNBC | Basal B | Torkinib | 0.0032 | uM | 15351.211 | 0.4502 | -0.0405 | 1.0866 | |||
| HCC38 | TNBC | Basal B | Torkinib | 0.016 | uM | 15351.211 | 0.1499 | -0.6512 | 1.0866 | |||
| HCC38 | TNBC | Basal B | Torkinib | 0.08 | uM | 15351.211 | 0.0867 | -0.7893 | 1.0866 | |||
| HCC38 | TNBC | Basal B | Torkinib | 0.4 | uM | 15351.211 | 0.0851 | -0.7929 | 1.0866 | |||
| HCC38 | TNBC | Basal B | Torkinib | 2 | uM | 15351.211 | 0.0778 | -0.8094 | 1.0866 | |||
| HCC38 | TNBC | Basal B | Torkinib | 10 | uM | 15351.211 | 0.0675 | -0.8328 | 1.0866 | |||
| HCC38 | TNBC | Basal B | Torkinib | 50 | uM | 15351.211 | 0.0281 | -0.9254 | 1.0866 | |||
| HCC70 | TNBC | Basal A | Torkinib | 0.000128 | uM | 15390.211 | 0.5866 | -0.3087 | 0.5021 | |||
| HCC70 | TNBC | Basal A | Torkinib | 0.00064 | uM | 15390.211 | 0.4030 | -0.6727 | 0.5021 | |||
| HCC70 | TNBC | Basal A | Torkinib | 0.0032 | uM | 15390.211 | 0.3134 | -0.8016 | 0.5021 | |||
| HCC70 | TNBC | Basal A | Torkinib | 0.016 | uM | 15390.211 | 0.2383 | -0.8851 | 0.5021 | |||
| HCC70 | TNBC | Basal A | Torkinib | 0.08 | uM | 15390.211 | 0.2008 | -0.9182 | 0.5021 | |||
| HCC70 | TNBC | Basal A | Torkinib | 0.4 | uM | 15390.211 | 0.1274 | -0.9670 | 0.5021 | |||
| HCC70 | TNBC | Basal A | Torkinib | 2 | uM | 15390.211 | 0.1023 | -0.9786 | 0.5021 | |||
| HCC70 | TNBC | Basal A | Torkinib | 10 | uM | 15390.211 | 0.0568 | -0.9934 | 0.5021 | |||
| HCC70 | TNBC | Basal A | Torkinib | 50 | uM | 15390.211 | 0.0441 | -0.9960 | 0.5021 | |||
| Hs 578T | TNBC | Basal B | Torkinib | 0.000128 | uM | 15352.211 | 1.0370 | 1.0289 | 2.5357 | |||
| Hs 578T | TNBC | Basal B | Torkinib | 0.00064 | uM | 15352.211 | 0.8528 | 0.8783 | 2.5357 | |||
| Hs 578T | TNBC | Basal B | Torkinib | 0.0032 | uM | 15352.211 | 0.9239 | 0.9385 | 2.5357 | |||
| Hs 578T | TNBC | Basal B | Torkinib | 0.016 | uM | 15352.211 | 0.6063 | 0.6418 | 2.5357 | |||
| Hs 578T | TNBC | Basal B | Torkinib | 0.08 | uM | 15352.211 | 0.6241 | 0.6607 | 2.5357 | |||
| Hs 578T | TNBC | Basal B | Torkinib | 0.4 | uM | 15352.211 | 0.2390 | 0.1373 | 2.5357 | |||
| Hs 578T | TNBC | Basal B | Torkinib | 2 | uM | 15352.211 | 0.1472 | -0.0605 | 2.5357 | |||
| Hs 578T | TNBC | Basal B | Torkinib | 10 | uM | 15352.211 | 0.1062 | -0.1741 | 2.5357 | |||
| Hs 578T | TNBC | Basal B | Torkinib | 50 | uM | 15352.211 | 0.0564 | -0.3566 | 2.5357 |