Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SUM52PE | HR+ | Luminal | TCS 2312 | CHK1 | CHK | 1.33 | uM | 10695.152 | 0.2413 | -0.3591 | 1.2495 | |
| SUM52PE | HR+ | Luminal | TCS 2312 | CHK1 | CHK | 6.67 | uM | 10695.152 | 0.1626 | -0.5327 | 1.2495 | |
| SUM52PE | HR+ | Luminal | TCS 2312 | CHK1 | CHK | 33.3 | uM | 10695.152 | 0.1293 | -0.6108 | 1.2495 | |
| SUM52PE | HR+ | Luminal | TCS 2312 | CHK1 | CHK | 0.0000853 | uM | 11852.159 | 1.0038 | 1.0057 | 1.3247 | |
| SUM52PE | HR+ | Luminal | TCS 2312 | CHK1 | CHK | 0.000427 | uM | 11852.159 | 1.0717 | 1.1073 | 1.3247 | |
| SUM52PE | HR+ | Luminal | TCS 2312 | CHK1 | CHK | 0.00213 | uM | 11852.159 | 0.9948 | 0.9921 | 1.3247 | |
| SUM52PE | HR+ | Luminal | TCS 2312 | CHK1 | CHK | 0.0107 | uM | 11852.159 | 0.9741 | 0.9607 | 1.3247 | |
| SUM52PE | HR+ | Luminal | TCS 2312 | CHK1 | CHK | 0.0533 | uM | 11852.159 | 0.9630 | 0.9439 | 1.3247 | |
| SUM52PE | HR+ | Luminal | TCS 2312 | CHK1 | CHK | 0.267 | uM | 11852.159 | 0.7930 | 0.6788 | 1.3247 | |
| SUM52PE | HR+ | Luminal | TCS 2312 | CHK1 | CHK | 1.33 | uM | 11852.159 | 0.2820 | -0.2309 | 1.3247 | |
| SUM52PE | HR+ | Luminal | TCS 2312 | CHK1 | CHK | 6.67 | uM | 11852.159 | 0.2939 | -0.2064 | 1.3247 | |
| SUM52PE | HR+ | Luminal | TCS 2312 | CHK1 | CHK | 33.3 | uM | 11852.159 | 0.1270 | -0.5787 | 1.3247 | |
| T47D | HR+ | Luminal | TCS 2312 | CHK1 | CHK | 0.0000853 | uM | 10939.152 | 0.9554 | 0.9469 | 1.6952 | |
| T47D | HR+ | Luminal | TCS 2312 | CHK1 | CHK | 0.000427 | uM | 10939.152 | 0.9406 | 0.9290 | 1.6952 | |
| T47D | HR+ | Luminal | TCS 2312 | CHK1 | CHK | 0.00213 | uM | 10939.152 | 0.9860 | 0.9834 | 1.6952 | |
| T47D | HR+ | Luminal | TCS 2312 | CHK1 | CHK | 0.0107 | uM | 10939.152 | 1.0274 | 1.0322 | 1.6952 | |
| T47D | HR+ | Luminal | TCS 2312 | CHK1 | CHK | 0.0533 | uM | 10939.152 | 1.0014 | 1.0017 | 1.6952 | |
| T47D | HR+ | Luminal | TCS 2312 | CHK1 | CHK | 0.267 | uM | 10939.152 | 1.0418 | 1.0489 | 1.6952 | |
| T47D | HR+ | Luminal | TCS 2312 | CHK1 | CHK | 1.33 | uM | 10939.152 | 0.5802 | 0.4506 | 1.6952 | |
| T47D | HR+ | Luminal | TCS 2312 | CHK1 | CHK | 6.67 | uM | 10939.152 | 0.3158 | 0.0133 | 1.6952 | |
| T47D | HR+ | Luminal | TCS 2312 | CHK1 | CHK | 33.3 | uM | 10939.152 | 0.3332 | 0.0458 | 1.6952 | |
| T47DKBLUC | Unknown | Unknown | TCS 2312 | CHK1 | CHK | 0.0000853 | uM | 12608.152 | 0.9855 | 0.9746 | 1.1477 | |
| T47DKBLUC | Unknown | Unknown | TCS 2312 | CHK1 | CHK | 0.000427 | uM | 12608.152 | 0.9758 | 0.9578 | 1.1477 | |
| T47DKBLUC | Unknown | Unknown | TCS 2312 | CHK1 | CHK | 0.00213 | uM | 12608.152 | 0.9681 | 0.9444 | 1.1477 | |
| T47DKBLUC | Unknown | Unknown | TCS 2312 | CHK1 | CHK | 0.0107 | uM | 12608.152 | 0.9817 | 0.9681 | 1.1477 |