Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1395 | TNBC | Basal B | TCS PIM-1 1 | Pim kinase | PIM | 0.213 | uM | 12000.135 | 0.9828 | 0.9504 | 0.6914 | |
| HCC1395 | TNBC | Basal B | TCS PIM-1 1 | Pim kinase | PIM | 1.07 | uM | 12000.135 | 0.9568 | 0.8762 | 0.6914 | |
| HCC1395 | TNBC | Basal B | TCS PIM-1 1 | Pim kinase | PIM | 5.33 | uM | 12000.135 | 1.0316 | 1.0920 | 0.6914 | |
| HCC1395 | TNBC | Basal B | TCS PIM-1 1 | Pim kinase | PIM | 26.7 | uM | 12000.135 | 0.9315 | 0.8048 | 0.6914 | |
| HCC1395 | TNBC | Basal B | TCS PIM-1 1 | Pim kinase | PIM | 133 | uM | 12000.135 | 0.8160 | 0.4905 | 0.6914 | |
| HCC1395 | TNBC | Basal B | TCS PIM-1 1 | Pim kinase | PIM | 0.000341 | uM | 12084.135 | 0.9378 | 0.9114 | 1.4162 | |
| HCC1395 | TNBC | Basal B | TCS PIM-1 1 | Pim kinase | PIM | 0.00171 | uM | 12084.135 | 0.9958 | 0.9940 | 1.4162 | |
| HCC1395 | TNBC | Basal B | TCS PIM-1 1 | Pim kinase | PIM | 0.00853 | uM | 12084.135 | 0.8857 | 0.8358 | 1.4162 | |
| HCC1395 | TNBC | Basal B | TCS PIM-1 1 | Pim kinase | PIM | 0.0427 | uM | 12084.135 | 0.9644 | 0.9494 | 1.4162 | |
| HCC1395 | TNBC | Basal B | TCS PIM-1 1 | Pim kinase | PIM | 0.213 | uM | 12084.135 | 0.8767 | 0.8225 | 1.4162 | |
| HCC1395 | TNBC | Basal B | TCS PIM-1 1 | Pim kinase | PIM | 1.07 | uM | 12084.135 | 0.9500 | 0.9289 | 1.4162 | |
| HCC1395 | TNBC | Basal B | TCS PIM-1 1 | Pim kinase | PIM | 5.33 | uM | 12084.135 | 0.9277 | 0.8968 | 1.4162 | |
| HCC1395 | TNBC | Basal B | TCS PIM-1 1 | Pim kinase | PIM | 26.7 | uM | 12084.135 | 0.9107 | 0.8722 | 1.4162 | |
| HCC1395 | TNBC | Basal B | TCS PIM-1 1 | Pim kinase | PIM | 133 | uM | 12084.135 | 0.8390 | 0.7668 | 1.4162 | |
| HCC1419 | HER2amp | Luminal | TCS PIM-1 1 | Pim kinase | PIM | 0.000341 | uM | 12001.135 | 0.9438 | 0.7559 | 0.4442 | |
| HCC1419 | HER2amp | Luminal | TCS PIM-1 1 | Pim kinase | PIM | 0.00171 | uM | 12001.135 | 0.9886 | 0.9489 | 0.4442 | |
| HCC1419 | HER2amp | Luminal | TCS PIM-1 1 | Pim kinase | PIM | 0.00853 | uM | 12001.135 | 0.9433 | 0.7537 | 0.4442 | |
| HCC1419 | HER2amp | Luminal | TCS PIM-1 1 | Pim kinase | PIM | 0.0427 | uM | 12001.135 | 0.9910 | 0.9597 | 0.4442 | |
| HCC1419 | HER2amp | Luminal | TCS PIM-1 1 | Pim kinase | PIM | 0.213 | uM | 12001.135 | 0.9728 | 0.8796 | 0.4442 | |
| HCC1419 | HER2amp | Luminal | TCS PIM-1 1 | Pim kinase | PIM | 1.07 | uM | 12001.135 | 1.0036 | 1.0161 | 0.4442 | |
| HCC1419 | HER2amp | Luminal | TCS PIM-1 1 | Pim kinase | PIM | 5.33 | uM | 12001.135 | 0.9687 | 0.8618 | 0.4442 | |
| HCC1419 | HER2amp | Luminal | TCS PIM-1 1 | Pim kinase | PIM | 26.7 | uM | 12001.135 | 0.9214 | 0.6634 | 0.4442 | |
| HCC1419 | HER2amp | Luminal | TCS PIM-1 1 | Pim kinase | PIM | 133 | uM | 12001.135 | 0.8267 | 0.3031 | 0.4442 | |
| HCC1428 | HR+ | Luminal | TCS PIM-1 1 | Pim kinase | PIM | 0.000171 | uM | 10693.148 | 1.0033 | 1.0073 | 0.8983 | |
| HCC1428 | HR+ | Luminal | TCS PIM-1 1 | Pim kinase | PIM | 0.000853 | uM | 10693.148 | 0.9681 | 0.9291 | 0.8983 |