Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MDA-MB-361 | HER2amp | Luminal | TCS 2312 | CHK1 | CHK | 0.00213 | uM | 10999.152 | 1.0358 | 1.0853 | 0.8426 | |
| MDA-MB-361 | HER2amp | Luminal | TCS 2312 | CHK1 | CHK | 0.0107 | uM | 10999.152 | 0.9941 | 0.9861 | 0.8426 | |
| MDA-MB-361 | HER2amp | Luminal | TCS 2312 | CHK1 | CHK | 0.0533 | uM | 10999.152 | 0.9834 | 0.9606 | 0.8426 | |
| MDA-MB-361 | HER2amp | Luminal | TCS 2312 | CHK1 | CHK | 0.267 | uM | 10999.152 | 0.8751 | 0.7070 | 0.8426 | |
| MDA-MB-361 | HER2amp | Luminal | TCS 2312 | CHK1 | CHK | 1.33 | uM | 10999.152 | 0.4418 | -0.2416 | 0.8426 | |
| MDA-MB-361 | HER2amp | Luminal | TCS 2312 | CHK1 | CHK | 6.67 | uM | 10999.152 | 0.3010 | -0.5190 | 0.8426 | |
| MDA-MB-361 | HER2amp | Luminal | TCS 2312 | CHK1 | CHK | 33.3 | uM | 10999.152 | 0.2545 | -0.6058 | 0.8426 | |
| MDA-MB-361 | HER2amp | Luminal | TCS 2312 | CHK1 | CHK | 0.0000853 | uM | 12379.152 | 1.0539 | 1.2084 | 0.5297 | |
| MDA-MB-361 | HER2amp | Luminal | TCS 2312 | CHK1 | CHK | 0.000427 | uM | 12379.152 | 1.0682 | 1.2653 | 0.5297 | |
| MDA-MB-361 | HER2amp | Luminal | TCS 2312 | CHK1 | CHK | 0.00213 | uM | 12379.152 | 1.0101 | 1.0382 | 0.5297 | |
| MDA-MB-361 | HER2amp | Luminal | TCS 2312 | CHK1 | CHK | 0.0107 | uM | 12379.152 | 1.0335 | 1.1285 | 0.5297 | |
| MDA-MB-361 | HER2amp | Luminal | TCS 2312 | CHK1 | CHK | 0.0533 | uM | 12379.152 | 1.0400 | 1.1535 | 0.5297 | |
| MDA-MB-361 | HER2amp | Luminal | TCS 2312 | CHK1 | CHK | 0.267 | uM | 12379.152 | 0.8666 | 0.5263 | 0.5297 | |
| MDA-MB-361 | HER2amp | Luminal | TCS 2312 | CHK1 | CHK | 1.33 | uM | 12379.152 | 0.0597 | -0.9902 | 0.5297 | |
| MDA-MB-361 | HER2amp | Luminal | TCS 2312 | CHK1 | CHK | 6.67 | uM | 12379.152 | 0.0381 | -0.9958 | 0.5297 | |
| MDA-MB-361 | HER2amp | Luminal | TCS 2312 | CHK1 | CHK | 33.3 | uM | 12379.152 | 0.0548 | -0.9917 | 0.5297 | |
| MDA-MB-415 | HR+ | Luminal | TCS 2312 | CHK1 | CHK | 0.0000853 | uM | 10938.152 | 0.9714 | 0.9398 | 0.9498 | |
| MDA-MB-415 | HR+ | Luminal | TCS 2312 | CHK1 | CHK | 0.000427 | uM | 10938.152 | 0.8597 | 0.7056 | 0.9498 | |
| MDA-MB-415 | HR+ | Luminal | TCS 2312 | CHK1 | CHK | 0.00213 | uM | 10938.152 | 0.9418 | 0.8777 | 0.9498 | |
| MDA-MB-415 | HR+ | Luminal | TCS 2312 | CHK1 | CHK | 0.0107 | uM | 10938.152 | 0.9652 | 0.9267 | 0.9498 | |
| MDA-MB-415 | HR+ | Luminal | TCS 2312 | CHK1 | CHK | 0.0533 | uM | 10938.152 | 0.9266 | 0.8458 | 0.9498 | |
| MDA-MB-415 | HR+ | Luminal | TCS 2312 | CHK1 | CHK | 0.267 | uM | 10938.152 | 0.6238 | 0.2167 | 0.9498 | |
| MDA-MB-415 | HR+ | Luminal | TCS 2312 | CHK1 | CHK | 1.33 | uM | 10938.152 | 0.4031 | -0.2317 | 0.9498 | |
| MDA-MB-415 | HR+ | Luminal | TCS 2312 | CHK1 | CHK | 6.67 | uM | 10938.152 | 0.1580 | -0.7134 | 0.9498 | |
| MDA-MB-415 | HR+ | Luminal | TCS 2312 | CHK1 | CHK | 33.3 | uM | 10938.152 | 0.1280 | -0.7704 | 0.9498 |