Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MDA-MB-175-VII | HR+ | Luminal | TCS 2312 | CHK1 | CHK | 0.0533 | uM | 10818.152 | 0.9999 | 0.9995 | 0.4535 | |
| MDA-MB-175-VII | HR+ | Luminal | TCS 2312 | CHK1 | CHK | 0.267 | uM | 10818.152 | 0.9641 | 0.8450 | 0.4535 | |
| MDA-MB-175-VII | HR+ | Luminal | TCS 2312 | CHK1 | CHK | 1.33 | uM | 10818.152 | 0.7954 | 0.2074 | 0.4535 | |
| MDA-MB-175-VII | HR+ | Luminal | TCS 2312 | CHK1 | CHK | 6.67 | uM | 10818.152 | 0.6736 | -0.1631 | 0.4535 | |
| MDA-MB-175-VII | HR+ | Luminal | TCS 2312 | CHK1 | CHK | 33.3 | uM | 10818.152 | 0.5684 | -0.4245 | 0.4535 | |
| MDA-MB-175-VII | HR+ | Luminal | TCS 2312 | CHK1 | CHK | 0.0000853 | uM | 12126.159 | 0.9584 | 0.8881 | 0.7389 | |
| MDA-MB-175-VII | HR+ | Luminal | TCS 2312 | CHK1 | CHK | 0.000427 | uM | 12126.159 | 0.9383 | 0.8348 | 0.7389 | |
| MDA-MB-175-VII | HR+ | Luminal | TCS 2312 | CHK1 | CHK | 0.00213 | uM | 12126.159 | 0.9107 | 0.7621 | 0.7389 | |
| MDA-MB-175-VII | HR+ | Luminal | TCS 2312 | CHK1 | CHK | 0.0107 | uM | 12126.159 | 0.9228 | 0.7940 | 0.7389 | |
| MDA-MB-175-VII | HR+ | Luminal | TCS 2312 | CHK1 | CHK | 0.0533 | uM | 12126.159 | 0.9709 | 0.9217 | 0.7389 | |
| MDA-MB-175-VII | HR+ | Luminal | TCS 2312 | CHK1 | CHK | 0.267 | uM | 12126.159 | 0.9208 | 0.7887 | 0.7389 | |
| MDA-MB-175-VII | HR+ | Luminal | TCS 2312 | CHK1 | CHK | 1.33 | uM | 12126.159 | 0.8625 | 0.6370 | 0.7389 | |
| MDA-MB-175-VII | HR+ | Luminal | TCS 2312 | CHK1 | CHK | 6.67 | uM | 12126.159 | 0.4315 | -0.3589 | 0.7389 | |
| MDA-MB-175-VII | HR+ | Luminal | TCS 2312 | CHK1 | CHK | 33.3 | uM | 12126.159 | 0.3728 | -0.4740 | 0.7389 | |
| MDA-MB-361 | HER2amp | Luminal | TCS 2312 | CHK1 | CHK | 0.0000853 | uM | 10643.14 | 1.0613 | 1.2485 | 0.5078 | |
| MDA-MB-361 | HER2amp | Luminal | TCS 2312 | CHK1 | CHK | 0.000427 | uM | 10643.14 | 1.0360 | 1.1442 | 0.5078 | |
| MDA-MB-361 | HER2amp | Luminal | TCS 2312 | CHK1 | CHK | 0.00213 | uM | 10643.14 | 1.0360 | 1.1442 | 0.5078 | |
| MDA-MB-361 | HER2amp | Luminal | TCS 2312 | CHK1 | CHK | 0.0107 | uM | 10643.14 | 1.0603 | 1.2444 | 0.5078 | |
| MDA-MB-361 | HER2amp | Luminal | TCS 2312 | CHK1 | CHK | 0.0533 | uM | 10643.14 | 1.0944 | 1.3890 | 0.5078 | |
| MDA-MB-361 | HER2amp | Luminal | TCS 2312 | CHK1 | CHK | 0.267 | uM | 10643.14 | 0.8072 | 0.3117 | 0.5078 | |
| MDA-MB-361 | HER2amp | Luminal | TCS 2312 | CHK1 | CHK | 1.33 | uM | 10643.14 | 0.3156 | -0.7936 | 0.5078 | |
| MDA-MB-361 | HER2amp | Luminal | TCS 2312 | CHK1 | CHK | 6.67 | uM | 10643.14 | 0.2646 | -0.8541 | 0.5078 | |
| MDA-MB-361 | HER2amp | Luminal | TCS 2312 | CHK1 | CHK | 33.3 | uM | 10643.14 | 0.0434 | -0.9959 | 0.5078 | |
| MDA-MB-361 | HER2amp | Luminal | TCS 2312 | CHK1 | CHK | 0.0000853 | uM | 10999.152 | 0.9799 | 0.9523 | 0.8426 | |
| MDA-MB-361 | HER2amp | Luminal | TCS 2312 | CHK1 | CHK | 0.000427 | uM | 10999.152 | 0.9443 | 0.8686 | 0.8426 |