Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| UACC-893 | HER2amp | Luminal | Taxol | TUBB | TUBB | 1.33 | uM | 9953.002 | 0.8622 | 0.3980 | 0.4141 | |
| UACC-893 | HER2amp | Luminal | Taxol | TUBB | TUBB | 6.67 | uM | 9953.002 | 0.8373 | 0.3024 | 0.4141 | |
| UACC-893 | HER2amp | Luminal | Taxol | TUBB | TUBB | 33.3 | uM | 9953.002 | 0.7419 | -0.0273 | 0.4141 | |
| ZR-75-1 | HR+ | Luminal | Taxol | TUBB | TUBB | 0.0000853 | uM | 7932.002 | 1.0535 | 1.1194 | 0.8992 | |
| ZR-75-1 | HR+ | Luminal | Taxol | TUBB | TUBB | 0.000427 | uM | 7932.002 | 1.0125 | 1.0279 | 0.8992 | |
| ZR-75-1 | HR+ | Luminal | Taxol | TUBB | TUBB | 0.00213 | uM | 7932.002 | 1.0203 | 1.0453 | 0.8992 | |
| ZR-75-1 | HR+ | Luminal | Taxol | TUBB | TUBB | 0.0107 | uM | 7932.002 | 0.8548 | 0.6797 | 0.8992 | |
| ZR-75-1 | HR+ | Luminal | Taxol | TUBB | TUBB | 0.0533 | uM | 7932.002 | 0.7119 | 0.3705 | 0.8992 | |
| ZR-75-1 | HR+ | Luminal | Taxol | TUBB | TUBB | 0.267 | uM | 7932.002 | 0.6549 | 0.2490 | 0.8992 | |
| ZR-75-1 | HR+ | Luminal | Taxol | TUBB | TUBB | 1.33 | uM | 7932.002 | 0.6670 | 0.2747 | 0.8992 | |
| ZR-75-1 | HR+ | Luminal | Taxol | TUBB | TUBB | 6.67 | uM | 7932.002 | 0.6366 | 0.2104 | 0.8992 | |
| ZR-75-1 | HR+ | Luminal | Taxol | TUBB | TUBB | 33.3 | uM | 7932.002 | 0.6349 | 0.2066 | 0.8992 | |
| ZR-75-1 | HR+ | Luminal | Taxol | TUBB | TUBB | 0.0000853 | uM | 9958.002 | 1.0170 | 1.0671 | 0.5113 | |
| ZR-75-1 | HR+ | Luminal | Taxol | TUBB | TUBB | 0.000427 | uM | 9958.002 | 0.9784 | 0.9164 | 0.5113 | |
| ZR-75-1 | HR+ | Luminal | Taxol | TUBB | TUBB | 0.00213 | uM | 9958.002 | 1.0082 | 1.0324 | 0.5113 | |
| ZR-75-1 | HR+ | Luminal | Taxol | TUBB | TUBB | 0.0107 | uM | 9958.002 | 0.8641 | 0.5032 | 0.5113 | |
| ZR-75-1 | HR+ | Luminal | Taxol | TUBB | TUBB | 0.0533 | uM | 9958.002 | 0.7757 | 0.2171 | 0.5113 | |
| ZR-75-1 | HR+ | Luminal | Taxol | TUBB | TUBB | 0.267 | uM | 9958.002 | 0.7576 | 0.1622 | 0.5113 | |
| ZR-75-1 | HR+ | Luminal | Taxol | TUBB | TUBB | 1.33 | uM | 9958.002 | 0.7561 | 0.1575 | 0.5113 | |
| ZR-75-1 | HR+ | Luminal | Taxol | TUBB | TUBB | 6.67 | uM | 9958.002 | 0.7446 | 0.1235 | 0.5113 | |
| ZR-75-1 | HR+ | Luminal | Taxol | TUBB | TUBB | 33.3 | uM | 9958.002 | 0.7959 | 0.2798 | 0.5113 | |
| ZR75B | HR+ | Luminal | Taxol | TUBB | TUBB | 0.0000853 | uM | 9972.002 | 1.0637 | 1.1268 | 1.0054 | |
| ZR75B | HR+ | Luminal | Taxol | TUBB | TUBB | 0.000427 | uM | 9972.002 | 0.9788 | 0.9578 | 1.0054 | |
| ZR75B | HR+ | Luminal | Taxol | TUBB | TUBB | 0.00213 | uM | 9972.002 | 0.9653 | 0.9309 | 1.0054 | |
| ZR75B | HR+ | Luminal | Taxol | TUBB | TUBB | 0.0107 | uM | 9972.002 | 0.6810 | 0.3649 | 1.0054 |