Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| UACC-812 | HER2amp | Luminal | Taxol | TUBB | TUBB | 33.3 | uM | 10267.002 | 0.5809 | -0.4735 | 0.4069 | |
| UACC-812 | HER2amp | Luminal | Taxol | TUBB | TUBB | 0.0000853 | uM | 13078.002 | 1.0199 | 1.0621 | 0.6437 | |
| UACC-812 | HER2amp | Luminal | Taxol | TUBB | TUBB | 0.000427 | uM | 13078.002 | 0.9767 | 0.9279 | 0.6437 | |
| UACC-812 | HER2amp | Luminal | Taxol | TUBB | TUBB | 0.00213 | uM | 13078.002 | 1.0524 | 1.1651 | 0.6437 | |
| UACC-812 | HER2amp | Luminal | Taxol | TUBB | TUBB | 0.0107 | uM | 13078.002 | 0.7174 | 0.1939 | 0.6437 | |
| UACC-812 | HER2amp | Luminal | Taxol | TUBB | TUBB | 0.0533 | uM | 13078.002 | 0.5499 | -0.2101 | 0.6437 | |
| UACC-812 | HER2amp | Luminal | Taxol | TUBB | TUBB | 0.267 | uM | 13078.002 | 0.4969 | -0.3252 | 0.6437 | |
| UACC-812 | HER2amp | Luminal | Taxol | TUBB | TUBB | 1.33 | uM | 13078.002 | 0.5081 | -0.3015 | 0.6437 | |
| UACC-812 | HER2amp | Luminal | Taxol | TUBB | TUBB | 6.67 | uM | 13078.002 | 0.4917 | -0.3363 | 0.6437 | |
| UACC-812 | HER2amp | Luminal | Taxol | TUBB | TUBB | 33.3 | uM | 13078.002 | 0.5050 | -0.3082 | 0.6437 | |
| UACC-893 | HER2amp | Luminal | Taxol | TUBB | TUBB | 0.0000853 | uM | 9933.002 | 1.1059 | 1.5270 | 0.4305 | |
| UACC-893 | HER2amp | Luminal | Taxol | TUBB | TUBB | 0.000427 | uM | 9933.002 | 0.9919 | 0.9624 | 0.4305 | |
| UACC-893 | HER2amp | Luminal | Taxol | TUBB | TUBB | 0.00213 | uM | 9933.002 | 1.0816 | 1.3998 | 0.4305 | |
| UACC-893 | HER2amp | Luminal | Taxol | TUBB | TUBB | 0.0107 | uM | 9933.002 | 0.9189 | 0.6431 | 0.4305 | |
| UACC-893 | HER2amp | Luminal | Taxol | TUBB | TUBB | 0.0533 | uM | 9933.002 | 0.4302 | -0.7181 | 0.4305 | |
| UACC-893 | HER2amp | Luminal | Taxol | TUBB | TUBB | 0.267 | uM | 9933.002 | 0.3990 | -0.7633 | 0.4305 | |
| UACC-893 | HER2amp | Luminal | Taxol | TUBB | TUBB | 1.33 | uM | 9933.002 | 0.4282 | -0.7211 | 0.4305 | |
| UACC-893 | HER2amp | Luminal | Taxol | TUBB | TUBB | 6.67 | uM | 9933.002 | 0.4115 | -0.7457 | 0.4305 | |
| UACC-893 | HER2amp | Luminal | Taxol | TUBB | TUBB | 33.3 | uM | 9933.002 | 0.4429 | -0.6984 | 0.4305 | |
| UACC-893 | HER2amp | Luminal | Taxol | TUBB | TUBB | 0.0000853 | uM | 9953.002 | 1.1078 | 1.5607 | 0.4141 | |
| UACC-893 | HER2amp | Luminal | Taxol | TUBB | TUBB | 0.000427 | uM | 9953.002 | 0.9261 | 0.6617 | 0.4141 | |
| UACC-893 | HER2amp | Luminal | Taxol | TUBB | TUBB | 0.00213 | uM | 9953.002 | 1.1511 | 1.8095 | 0.4141 | |
| UACC-893 | HER2amp | Luminal | Taxol | TUBB | TUBB | 0.0107 | uM | 9953.002 | 0.9570 | 0.7984 | 0.4141 | |
| UACC-893 | HER2amp | Luminal | Taxol | TUBB | TUBB | 0.0533 | uM | 9953.002 | 0.8790 | 0.4647 | 0.4141 | |
| UACC-893 | HER2amp | Luminal | Taxol | TUBB | TUBB | 0.267 | uM | 9953.002 | 0.8062 | 0.1889 | 0.4141 |