Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MDA-MB-468 | TNBC | Basal A | Taxol | TUBB | TUBB | 33.3 | uM | 7907.002 | 0.0411 | -0.7287 | 1.5984 | |
| SK-BR-3 | HER2amp | Luminal | Taxol | TUBB | TUBB | 0.0000853 | uM | 9759.002 | 1.0670 | 1.1177 | 1.1336 | |
| SK-BR-3 | HER2amp | Luminal | Taxol | TUBB | TUBB | 0.000427 | uM | 9759.002 | 1.0900 | 1.1579 | 1.1336 | |
| SK-BR-3 | HER2amp | Luminal | Taxol | TUBB | TUBB | 0.00213 | uM | 9759.002 | 1.0734 | 1.1289 | 1.1336 | |
| SK-BR-3 | HER2amp | Luminal | Taxol | TUBB | TUBB | 0.0107 | uM | 9759.002 | 0.7447 | 0.5420 | 1.1336 | |
| SK-BR-3 | HER2amp | Luminal | Taxol | TUBB | TUBB | 0.0533 | uM | 9759.002 | 0.1482 | -0.6288 | 1.1336 | |
| SK-BR-3 | HER2amp | Luminal | Taxol | TUBB | TUBB | 0.267 | uM | 9759.002 | 0.1390 | -0.6491 | 1.1336 | |
| SK-BR-3 | HER2amp | Luminal | Taxol | TUBB | TUBB | 1.33 | uM | 9759.002 | 0.1487 | -0.6278 | 1.1336 | |
| SK-BR-3 | HER2amp | Luminal | Taxol | TUBB | TUBB | 6.67 | uM | 9759.002 | 0.1306 | -0.6681 | 1.1336 | |
| SK-BR-3 | HER2amp | Luminal | Taxol | TUBB | TUBB | 33.3 | uM | 9759.002 | 0.1264 | -0.6775 | 1.1336 | |
| SK-BR-3 | HER2amp | Luminal | Taxol | TUBB | TUBB | 0.0000853 | uM | 9760.002 | 1.0100 | 1.0202 | 0.9910 | |
| SK-BR-3 | HER2amp | Luminal | Taxol | TUBB | TUBB | 0.000427 | uM | 9760.002 | 0.9754 | 0.9503 | 0.9910 | |
| SK-BR-3 | HER2amp | Luminal | Taxol | TUBB | TUBB | 0.00213 | uM | 9760.002 | 0.9786 | 0.9568 | 0.9910 | |
| SK-BR-3 | HER2amp | Luminal | Taxol | TUBB | TUBB | 0.0107 | uM | 9760.002 | 0.7695 | 0.5353 | 0.9910 | |
| SK-BR-3 | HER2amp | Luminal | Taxol | TUBB | TUBB | 0.0533 | uM | 9760.002 | 0.1408 | -0.7233 | 0.9910 | |
| SK-BR-3 | HER2amp | Luminal | Taxol | TUBB | TUBB | 0.267 | uM | 9760.002 | 0.1563 | -0.6927 | 0.9910 | |
| SK-BR-3 | HER2amp | Luminal | Taxol | TUBB | TUBB | 1.33 | uM | 9760.002 | 0.1442 | -0.7167 | 0.9910 | |
| SK-BR-3 | HER2amp | Luminal | Taxol | TUBB | TUBB | 6.67 | uM | 9760.002 | 0.1435 | -0.7181 | 0.9910 | |
| SK-BR-3 | HER2amp | Luminal | Taxol | TUBB | TUBB | 33.3 | uM | 9760.002 | 0.1225 | -0.7597 | 0.9910 | |
| SK-BR-3 | HER2amp | Luminal | Taxol | TUBB | TUBB | 0.0000853 | uM | 10127.002 | 1.0085 | 1.0255 | 0.6658 | |
| SK-BR-3 | HER2amp | Luminal | Taxol | TUBB | TUBB | 0.000427 | uM | 10127.002 | 0.9701 | 0.9108 | 0.6658 | |
| SK-BR-3 | HER2amp | Luminal | Taxol | TUBB | TUBB | 0.00213 | uM | 10127.002 | 1.0710 | 1.2169 | 0.6658 | |
| SK-BR-3 | HER2amp | Luminal | Taxol | TUBB | TUBB | 0.0107 | uM | 10127.002 | 0.7294 | 0.2450 | 0.6658 | |
| SK-BR-3 | HER2amp | Luminal | Taxol | TUBB | TUBB | 0.0533 | uM | 10127.002 | 0.6303 | -0.0001 | 0.6658 | |
| SK-BR-3 | HER2amp | Luminal | Taxol | TUBB | TUBB | 0.267 | uM | 10127.002 | 0.3320 | -0.6182 | 0.6658 |