Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ZR75B | HR+ | Luminal | Taxol | TUBB | TUBB | 0.0533 | uM | 9972.002 | 0.6241 | 0.2514 | 1.0054 | |
| ZR75B | HR+ | Luminal | Taxol | TUBB | TUBB | 0.267 | uM | 9972.002 | 0.5747 | 0.1528 | 1.0054 | |
| ZR75B | HR+ | Luminal | Taxol | TUBB | TUBB | 1.33 | uM | 9972.002 | 0.6217 | 0.2465 | 1.0054 | |
| ZR75B | HR+ | Luminal | Taxol | TUBB | TUBB | 6.67 | uM | 9972.002 | 0.5806 | 0.1646 | 1.0054 | |
| ZR75B | HR+ | Luminal | Taxol | TUBB | TUBB | 33.3 | uM | 9972.002 | 0.5526 | 0.1087 | 1.0054 | |
| ZR75B | HR+ | Luminal | Taxol | TUBB | TUBB | 0.0000853 | uM | 9997.002 | 1.0004 | 1.0009 | 0.9751 | |
| ZR75B | HR+ | Luminal | Taxol | TUBB | TUBB | 0.000427 | uM | 9997.002 | 0.9937 | 0.9870 | 0.9751 | |
| ZR75B | HR+ | Luminal | Taxol | TUBB | TUBB | 0.00213 | uM | 9997.002 | 1.0440 | 1.0903 | 0.9751 | |
| ZR75B | HR+ | Luminal | Taxol | TUBB | TUBB | 0.0107 | uM | 9997.002 | 0.8154 | 0.6223 | 0.9751 | |
| ZR75B | HR+ | Luminal | Taxol | TUBB | TUBB | 0.0533 | uM | 9997.002 | 0.7892 | 0.5688 | 0.9751 | |
| ZR75B | HR+ | Luminal | Taxol | TUBB | TUBB | 0.267 | uM | 9997.002 | 0.6896 | 0.3661 | 0.9751 | |
| ZR75B | HR+ | Luminal | Taxol | TUBB | TUBB | 1.33 | uM | 9997.002 | 0.7454 | 0.4796 | 0.9751 | |
| ZR75B | HR+ | Luminal | Taxol | TUBB | TUBB | 6.67 | uM | 9997.002 | 0.6405 | 0.2665 | 0.9751 | |
| ZR75B | HR+ | Luminal | Taxol | TUBB | TUBB | 33.3 | uM | 9997.002 | 0.5604 | 0.1042 | 0.9751 | |
| 184A1 | NM | Basal | TCS 2312 | CHK1 | CHK | 0.0000853 | uM | 12509.152 | 1.0107 | 1.0155 | 1.3755 | |
| 184A1 | NM | Basal | TCS 2312 | CHK1 | CHK | 0.000427 | uM | 12509.152 | 1.0411 | 1.0594 | 1.3755 | |
| 184A1 | NM | Basal | TCS 2312 | CHK1 | CHK | 0.00213 | uM | 12509.152 | 0.9693 | 0.9551 | 1.3755 | |
| 184A1 | NM | Basal | TCS 2312 | CHK1 | CHK | 0.0107 | uM | 12509.152 | 1.0070 | 1.0102 | 1.3755 | |
| 184A1 | NM | Basal | TCS 2312 | CHK1 | CHK | 0.0533 | uM | 12509.152 | 1.0535 | 1.0772 | 1.3755 | |
| 184A1 | NM | Basal | TCS 2312 | CHK1 | CHK | 0.267 | uM | 12509.152 | 0.8998 | 0.8522 | 1.3755 | |
| 184A1 | NM | Basal | TCS 2312 | CHK1 | CHK | 1.33 | uM | 12509.152 | 0.3113 | -0.1438 | 1.3755 | |
| 184A1 | NM | Basal | TCS 2312 | CHK1 | CHK | 6.67 | uM | 12509.152 | 0.3043 | -0.1579 | 1.3755 | |
| 184A1 | NM | Basal | TCS 2312 | CHK1 | CHK | 33.3 | uM | 12509.152 | 0.1083 | -0.6028 | 1.3755 | |
| 184B5 | NM | Basal | TCS 2312 | CHK1 | CHK | 0.0000853 | uM | 12566.152 | 1.0503 | 1.0673 | 1.4827 | |
| 184B5 | NM | Basal | TCS 2312 | CHK1 | CHK | 0.000427 | uM | 12566.152 | 0.9688 | 0.9577 | 1.4827 |