Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MDA-MB-415 | HR+ | Luminal | Taxol | TUBB | TUBB | 6.67 | uM | 9664.002 | 0.4648 | -0.4486 | 0.5947 | |
| MDA-MB-415 | HR+ | Luminal | Taxol | TUBB | TUBB | 33.3 | uM | 9664.002 | 0.4797 | -0.4185 | 0.5947 | |
| MDA-MB-415 | HR+ | Luminal | Taxol | TUBB | TUBB | 0.0000853 | uM | 12959.002 | 1.0868 | 1.4889 | 0.3805 | |
| MDA-MB-415 | HR+ | Luminal | Taxol | TUBB | TUBB | 0.000427 | uM | 12959.002 | 1.0118 | 1.0627 | 0.3805 | |
| MDA-MB-415 | HR+ | Luminal | Taxol | TUBB | TUBB | 0.00213 | uM | 12959.002 | 1.0752 | 1.4196 | 0.3805 | |
| MDA-MB-415 | HR+ | Luminal | Taxol | TUBB | TUBB | 0.0107 | uM | 12959.002 | 0.9113 | 0.5670 | 0.3805 | |
| MDA-MB-415 | HR+ | Luminal | Taxol | TUBB | TUBB | 0.0533 | uM | 12959.002 | 0.7555 | -0.0428 | 0.3805 | |
| MDA-MB-415 | HR+ | Luminal | Taxol | TUBB | TUBB | 0.267 | uM | 12959.002 | 0.7293 | -0.1275 | 0.3805 | |
| MDA-MB-415 | HR+ | Luminal | Taxol | TUBB | TUBB | 1.33 | uM | 12959.002 | 0.7035 | -0.2064 | 0.3805 | |
| MDA-MB-415 | HR+ | Luminal | Taxol | TUBB | TUBB | 6.67 | uM | 12959.002 | 0.7098 | -0.1876 | 0.3805 | |
| MDA-MB-415 | HR+ | Luminal | Taxol | TUBB | TUBB | 33.3 | uM | 12959.002 | 0.6707 | -0.2999 | 0.3805 | |
| MDA-MB-436 | TNBC | Basal B | Taxol | TUBB | TUBB | 0.0000853 | uM | 7898.002 | 1.1097 | 1.1925 | 1.1328 | |
| MDA-MB-436 | TNBC | Basal B | Taxol | TUBB | TUBB | 0.000427 | uM | 7898.002 | 0.9708 | 0.9483 | 1.1328 | |
| MDA-MB-436 | TNBC | Basal B | Taxol | TUBB | TUBB | 0.00213 | uM | 7898.002 | 1.1105 | 1.1940 | 1.1328 | |
| MDA-MB-436 | TNBC | Basal B | Taxol | TUBB | TUBB | 0.0107 | uM | 7898.002 | 0.9824 | 0.9690 | 1.1328 | |
| MDA-MB-436 | TNBC | Basal B | Taxol | TUBB | TUBB | 0.0533 | uM | 7898.002 | 0.4984 | 0.0816 | 1.1328 | |
| MDA-MB-436 | TNBC | Basal B | Taxol | TUBB | TUBB | 0.267 | uM | 7898.002 | 0.3702 | -0.1682 | 1.1328 | |
| MDA-MB-436 | TNBC | Basal B | Taxol | TUBB | TUBB | 1.33 | uM | 7898.002 | 0.3952 | -0.1187 | 1.1328 | |
| MDA-MB-436 | TNBC | Basal B | Taxol | TUBB | TUBB | 6.67 | uM | 7898.002 | 0.3855 | -0.1378 | 1.1328 | |
| MDA-MB-436 | TNBC | Basal B | Taxol | TUBB | TUBB | 33.3 | uM | 7898.002 | 0.3415 | -0.2253 | 1.1328 | |
| MDA-MB-436 | TNBC | Basal B | Taxol | TUBB | TUBB | 0.0000853 | uM | 7900.002 | 1.4719 | 3.5145 | 0.4748 | |
| MDA-MB-436 | TNBC | Basal B | Taxol | TUBB | TUBB | 0.000427 | uM | 7900.002 | 0.9584 | 0.8288 | 0.4748 | |
| MDA-MB-436 | TNBC | Basal B | Taxol | TUBB | TUBB | 0.00213 | uM | 7900.002 | 1.4758 | 3.5398 | 0.4748 | |
| MDA-MB-436 | TNBC | Basal B | Taxol | TUBB | TUBB | 0.0107 | uM | 7900.002 | 1.0640 | 1.2790 | 0.4748 | |
| MDA-MB-436 | TNBC | Basal B | Taxol | TUBB | TUBB | 0.0533 | uM | 7900.002 | 0.8730 | 0.5024 | 0.4748 |