Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MDA-MB-436 | TNBC | Basal B | Taxol | TUBB | TUBB | 0.267 | uM | 7900.002 | 0.5361 | -0.4620 | 0.4748 | |
| MDA-MB-436 | TNBC | Basal B | Taxol | TUBB | TUBB | 1.33 | uM | 7900.002 | 0.7182 | -0.0041 | 0.4748 | |
| MDA-MB-436 | TNBC | Basal B | Taxol | TUBB | TUBB | 6.67 | uM | 7900.002 | 0.5279 | -0.4792 | 0.4748 | |
| MDA-MB-436 | TNBC | Basal B | Taxol | TUBB | TUBB | 33.3 | uM | 7900.002 | 0.5283 | -0.4784 | 0.4748 | |
| MDA-MB-436 | TNBC | Basal B | Taxol | TUBB | TUBB | 0.0000853 | uM | 10266.002 | 1.1700 | 1.5230 | 0.6757 | |
| MDA-MB-436 | TNBC | Basal B | Taxol | TUBB | TUBB | 0.000427 | uM | 10266.002 | 0.9211 | 0.7709 | 0.6757 | |
| MDA-MB-436 | TNBC | Basal B | Taxol | TUBB | TUBB | 0.00213 | uM | 10266.002 | 1.0994 | 1.3010 | 0.6757 | |
| MDA-MB-436 | TNBC | Basal B | Taxol | TUBB | TUBB | 0.0107 | uM | 10266.002 | 0.8391 | 0.5426 | 0.6757 | |
| MDA-MB-436 | TNBC | Basal B | Taxol | TUBB | TUBB | 0.0533 | uM | 10266.002 | 0.5930 | -0.0770 | 0.6757 | |
| MDA-MB-436 | TNBC | Basal B | Taxol | TUBB | TUBB | 0.267 | uM | 10266.002 | 0.5600 | -0.1522 | 0.6757 | |
| MDA-MB-436 | TNBC | Basal B | Taxol | TUBB | TUBB | 1.33 | uM | 10266.002 | 0.5410 | -0.1944 | 0.6757 | |
| MDA-MB-436 | TNBC | Basal B | Taxol | TUBB | TUBB | 6.67 | uM | 10266.002 | 0.4480 | -0.3906 | 0.6757 | |
| MDA-MB-436 | TNBC | Basal B | Taxol | TUBB | TUBB | 33.3 | uM | 10266.002 | 0.3292 | -0.6138 | 0.6757 | |
| MDA-MB-453 | TNBC | Luminal | Taxol | TUBB | TUBB | 0.0000853 | uM | 7903.002 | 0.9416 | 0.9038 | 1.2202 | |
| MDA-MB-453 | TNBC | Luminal | Taxol | TUBB | TUBB | 0.000427 | uM | 7903.002 | 0.9194 | 0.8669 | 1.2202 | |
| MDA-MB-453 | TNBC | Luminal | Taxol | TUBB | TUBB | 0.00213 | uM | 7903.002 | 0.9742 | 0.9577 | 1.2202 | |
| MDA-MB-453 | TNBC | Luminal | Taxol | TUBB | TUBB | 0.0107 | uM | 7903.002 | 0.4305 | 0.0025 | 1.2202 | |
| MDA-MB-453 | TNBC | Luminal | Taxol | TUBB | TUBB | 0.0533 | uM | 7903.002 | 0.1972 | -0.4713 | 1.2202 | |
| MDA-MB-453 | TNBC | Luminal | Taxol | TUBB | TUBB | 0.267 | uM | 7903.002 | 0.1738 | -0.5234 | 1.2202 | |
| MDA-MB-453 | TNBC | Luminal | Taxol | TUBB | TUBB | 1.33 | uM | 7903.002 | 0.1963 | -0.4734 | 1.2202 | |
| MDA-MB-453 | TNBC | Luminal | Taxol | TUBB | TUBB | 6.67 | uM | 7903.002 | 0.1831 | -0.5025 | 1.2202 | |
| MDA-MB-453 | TNBC | Luminal | Taxol | TUBB | TUBB | 33.3 | uM | 7903.002 | 0.2457 | -0.3671 | 1.2202 | |
| MDA-MB-453 | TNBC | Luminal | Taxol | TUBB | TUBB | 0.0000853 | uM | 9708.002 | 1.1481 | 1.2817 | 1.0482 | |
| MDA-MB-453 | TNBC | Luminal | Taxol | TUBB | TUBB | 0.000427 | uM | 9708.002 | 1.0606 | 1.1156 | 1.0482 | |
| MDA-MB-453 | TNBC | Luminal | Taxol | TUBB | TUBB | 0.00213 | uM | 9708.002 | 1.1397 | 1.2657 | 1.0482 |