Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
Download: Excel (XLSX), Comma-separated (CSV)
Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
---|---|---|---|---|---|---|---|---|---|---|---|---|
MDA-MB-361 | HER2amp | Luminal | Taxol | TUBB | TUBB | 0.0000853 | uM | 12989.002 | 1.0131 | 1.0436 | 0.6028 | |
MDA-MB-361 | HER2amp | Luminal | Taxol | TUBB | TUBB | 0.000427 | uM | 12989.002 | 0.9637 | 0.8810 | 0.6028 | |
MDA-MB-361 | HER2amp | Luminal | Taxol | TUBB | TUBB | 0.00213 | uM | 12989.002 | 1.0321 | 1.1076 | 0.6028 | |
MDA-MB-361 | HER2amp | Luminal | Taxol | TUBB | TUBB | 0.0107 | uM | 12989.002 | 0.9678 | 0.8943 | 0.6028 | |
MDA-MB-361 | HER2amp | Luminal | Taxol | TUBB | TUBB | 0.0533 | uM | 12989.002 | 0.5864 | -0.1751 | 0.6028 | |
MDA-MB-361 | HER2amp | Luminal | Taxol | TUBB | TUBB | 0.267 | uM | 12989.002 | 0.5562 | -0.2442 | 0.6028 | |
MDA-MB-361 | HER2amp | Luminal | Taxol | TUBB | TUBB | 1.33 | uM | 12989.002 | 0.5728 | -0.2064 | 0.6028 | |
MDA-MB-361 | HER2amp | Luminal | Taxol | TUBB | TUBB | 6.67 | uM | 12989.002 | 0.5678 | -0.2179 | 0.6028 | |
MDA-MB-361 | HER2amp | Luminal | Taxol | TUBB | TUBB | 33.3 | uM | 12989.002 | 0.5322 | -0.2976 | 0.6028 | |
MDA-MB-415 | HR+ | Luminal | Taxol | TUBB | TUBB | 0.0000853 | uM | 7897.002 | 1.0277 | 1.0662 | 0.8381 | |
MDA-MB-415 | HR+ | Luminal | Taxol | TUBB | TUBB | 0.000427 | uM | 7897.002 | 0.9233 | 0.8184 | 0.8381 | |
MDA-MB-415 | HR+ | Luminal | Taxol | TUBB | TUBB | 0.00213 | uM | 7897.002 | 0.9028 | 0.7702 | 0.8381 | |
MDA-MB-415 | HR+ | Luminal | Taxol | TUBB | TUBB | 0.0107 | uM | 7897.002 | 0.7069 | 0.3222 | 0.8381 | |
MDA-MB-415 | HR+ | Luminal | Taxol | TUBB | TUBB | 0.0533 | uM | 7897.002 | 0.6257 | 0.1430 | 0.8381 | |
MDA-MB-415 | HR+ | Luminal | Taxol | TUBB | TUBB | 0.267 | uM | 7897.002 | 0.5566 | -0.0060 | 0.8381 | |
MDA-MB-415 | HR+ | Luminal | Taxol | TUBB | TUBB | 1.33 | uM | 7897.002 | 0.5980 | 0.0830 | 0.8381 | |
MDA-MB-415 | HR+ | Luminal | Taxol | TUBB | TUBB | 6.67 | uM | 7897.002 | 0.5168 | -0.0901 | 0.8381 | |
MDA-MB-415 | HR+ | Luminal | Taxol | TUBB | TUBB | 33.3 | uM | 7897.002 | 0.5336 | -0.0548 | 0.8381 | |
MDA-MB-415 | HR+ | Luminal | Taxol | TUBB | TUBB | 0.0000853 | uM | 9664.002 | 0.9841 | 0.9469 | 0.5947 | |
MDA-MB-415 | HR+ | Luminal | Taxol | TUBB | TUBB | 0.000427 | uM | 9664.002 | 0.9302 | 0.7708 | 0.5947 | |
MDA-MB-415 | HR+ | Luminal | Taxol | TUBB | TUBB | 0.00213 | uM | 9664.002 | 0.9423 | 0.8097 | 0.5947 | |
MDA-MB-415 | HR+ | Luminal | Taxol | TUBB | TUBB | 0.0107 | uM | 9664.002 | 0.6696 | 0.0189 | 0.5947 | |
MDA-MB-415 | HR+ | Luminal | Taxol | TUBB | TUBB | 0.0533 | uM | 9664.002 | 0.5851 | -0.1880 | 0.5947 | |
MDA-MB-415 | HR+ | Luminal | Taxol | TUBB | TUBB | 0.267 | uM | 9664.002 | 0.4684 | -0.4413 | 0.5947 | |
MDA-MB-415 | HR+ | Luminal | Taxol | TUBB | TUBB | 1.33 | uM | 9664.002 | 0.4987 | -0.3793 | 0.5947 |