Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MDA-MB-361 | HER2amp | Luminal | Taxol | TUBB | TUBB | 0.00213 | uM | 7896.002 | 1.0772 | 1.1343 | 1.1441 | |
| MDA-MB-361 | HER2amp | Luminal | Taxol | TUBB | TUBB | 0.0107 | uM | 7896.002 | 0.8270 | 0.6940 | 1.1441 | |
| MDA-MB-361 | HER2amp | Luminal | Taxol | TUBB | TUBB | 0.0533 | uM | 7896.002 | 0.4897 | 0.0716 | 1.1441 | |
| MDA-MB-361 | HER2amp | Luminal | Taxol | TUBB | TUBB | 0.267 | uM | 7896.002 | 0.4048 | -0.0927 | 1.1441 | |
| MDA-MB-361 | HER2amp | Luminal | Taxol | TUBB | TUBB | 1.33 | uM | 7896.002 | 0.3541 | -0.1929 | 1.1441 | |
| MDA-MB-361 | HER2amp | Luminal | Taxol | TUBB | TUBB | 6.67 | uM | 7896.002 | 0.3333 | -0.2345 | 1.1441 | |
| MDA-MB-361 | HER2amp | Luminal | Taxol | TUBB | TUBB | 33.3 | uM | 7896.002 | 0.3270 | -0.2472 | 1.1441 | |
| MDA-MB-361 | HER2amp | Luminal | Taxol | TUBB | TUBB | 0.0000853 | uM | 9648.002 | 1.0717 | 1.2261 | 0.6465 | |
| MDA-MB-361 | HER2amp | Luminal | Taxol | TUBB | TUBB | 0.000427 | uM | 9648.002 | 1.0065 | 1.0200 | 0.6465 | |
| MDA-MB-361 | HER2amp | Luminal | Taxol | TUBB | TUBB | 0.00213 | uM | 9648.002 | 1.0250 | 1.0778 | 0.6465 | |
| MDA-MB-361 | HER2amp | Luminal | Taxol | TUBB | TUBB | 0.0107 | uM | 9648.002 | 0.7576 | 0.3018 | 0.6465 | |
| MDA-MB-361 | HER2amp | Luminal | Taxol | TUBB | TUBB | 0.0533 | uM | 9648.002 | 0.5784 | -0.1424 | 0.6465 | |
| MDA-MB-361 | HER2amp | Luminal | Taxol | TUBB | TUBB | 0.267 | uM | 9648.002 | 0.4933 | -0.3296 | 0.6465 | |
| MDA-MB-361 | HER2amp | Luminal | Taxol | TUBB | TUBB | 1.33 | uM | 9648.002 | 0.4714 | -0.3750 | 0.6465 | |
| MDA-MB-361 | HER2amp | Luminal | Taxol | TUBB | TUBB | 6.67 | uM | 9648.002 | 0.4490 | -0.4204 | 0.6465 | |
| MDA-MB-361 | HER2amp | Luminal | Taxol | TUBB | TUBB | 33.3 | uM | 9648.002 | 0.4256 | -0.4664 | 0.6465 | |
| MDA-MB-361 | HER2amp | Luminal | Taxol | TUBB | TUBB | 0.0000853 | uM | 10095.002 | 1.0105 | 1.0222 | 0.9451 | |
| MDA-MB-361 | HER2amp | Luminal | Taxol | TUBB | TUBB | 0.000427 | uM | 10095.002 | 0.9729 | 0.9428 | 0.9451 | |
| MDA-MB-361 | HER2amp | Luminal | Taxol | TUBB | TUBB | 0.00213 | uM | 10095.002 | 1.0212 | 1.0449 | 0.9451 | |
| MDA-MB-361 | HER2amp | Luminal | Taxol | TUBB | TUBB | 0.0107 | uM | 10095.002 | 0.7457 | 0.4663 | 0.9451 | |
| MDA-MB-361 | HER2amp | Luminal | Taxol | TUBB | TUBB | 0.0533 | uM | 10095.002 | 0.5387 | 0.0395 | 0.9451 | |
| MDA-MB-361 | HER2amp | Luminal | Taxol | TUBB | TUBB | 0.267 | uM | 10095.002 | 0.4034 | -0.2346 | 0.9451 | |
| MDA-MB-361 | HER2amp | Luminal | Taxol | TUBB | TUBB | 1.33 | uM | 10095.002 | 0.4392 | -0.1625 | 0.9451 | |
| MDA-MB-361 | HER2amp | Luminal | Taxol | TUBB | TUBB | 6.67 | uM | 10095.002 | 0.4115 | -0.2184 | 0.9451 | |
| MDA-MB-361 | HER2amp | Luminal | Taxol | TUBB | TUBB | 33.3 | uM | 10095.002 | 0.3705 | -0.3006 | 0.9451 |