Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset - HMS LINCS Database

Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)

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Small molecules	Cells	Antibodies

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Cell	Clinical Subtype	Transcriptional Subtype	Small Molecule	Perturbagen Target	Perturbagen Class	Perturbagen Concentration	Perturbagen Conc Unit	Biological Replicate ID	Relative Cell Count	Normalized Growth Rate Inhibition Value	Nominal Division Rate
MDA-MB-175-VII	HR+	Luminal	Taxol	TUBB	TUBB	0.0533	uM	7886.002	0.7391	0.3122	0.7173
MDA-MB-175-VII	HR+	Luminal	Taxol	TUBB	TUBB	0.267	uM	7886.002	0.7305	0.2909	0.7173
MDA-MB-175-VII	HR+	Luminal	Taxol	TUBB	TUBB	1.33	uM	7886.002	0.7844	0.4255	0.7173
MDA-MB-175-VII	HR+	Luminal	Taxol	TUBB	TUBB	6.67	uM	7886.002	0.7164	0.2562	0.7173
MDA-MB-175-VII	HR+	Luminal	Taxol	TUBB	TUBB	33.3	uM	7886.002	0.7378	0.3089	0.7173
MDA-MB-231	TNBC	Basal B	Taxol	TUBB	TUBB	0.0000853	uM	7892.002	1.0147	1.0121	2.4193
MDA-MB-231	TNBC	Basal B	Taxol	TUBB	TUBB	0.000427	uM	7892.002	1.0718	1.0582	2.4193
MDA-MB-231	TNBC	Basal B	Taxol	TUBB	TUBB	0.00213	uM	7892.002	0.9659	0.9715	2.4193
MDA-MB-231	TNBC	Basal B	Taxol	TUBB	TUBB	0.0107	uM	7892.002	0.6187	0.6400	2.4193
MDA-MB-231	TNBC	Basal B	Taxol	TUBB	TUBB	0.0533	uM	7892.002	0.3293	0.2637	2.4193
MDA-MB-231	TNBC	Basal B	Taxol	TUBB	TUBB	0.267	uM	7892.002	0.2356	0.1004	2.4193
MDA-MB-231	TNBC	Basal B	Taxol	TUBB	TUBB	1.33	uM	7892.002	0.2180	0.0656	2.4193
MDA-MB-231	TNBC	Basal B	Taxol	TUBB	TUBB	6.67	uM	7892.002	0.2128	0.0551	2.4193
MDA-MB-231	TNBC	Basal B	Taxol	TUBB	TUBB	33.3	uM	7892.002	0.1690	-0.0409	2.4193
MDA-MB-231	TNBC	Basal B	Taxol	TUBB	TUBB	0.0000853	uM	7893.002	0.9535	0.9598	2.3454
MDA-MB-231	TNBC	Basal B	Taxol	TUBB	TUBB	0.000427	uM	7893.002	1.0024	1.0020	2.3454
MDA-MB-231	TNBC	Basal B	Taxol	TUBB	TUBB	0.00213	uM	7893.002	0.8645	0.8796	2.3454
MDA-MB-231	TNBC	Basal B	Taxol	TUBB	TUBB	0.0107	uM	7893.002	0.4937	0.4802	2.3454
MDA-MB-231	TNBC	Basal B	Taxol	TUBB	TUBB	0.0533	uM	7893.002	0.3375	0.2587	2.3454
MDA-MB-231	TNBC	Basal B	Taxol	TUBB	TUBB	0.267	uM	7893.002	0.2386	0.0856	2.3454
MDA-MB-231	TNBC	Basal B	Taxol	TUBB	TUBB	1.33	uM	7893.002	0.2486	0.1049	2.3454
MDA-MB-231	TNBC	Basal B	Taxol	TUBB	TUBB	6.67	uM	7893.002	0.2430	0.0942	2.3454
MDA-MB-231	TNBC	Basal B	Taxol	TUBB	TUBB	33.3	uM	7893.002	0.1366	-0.1441	2.3454
MDA-MB-361	HER2amp	Luminal	Taxol	TUBB	TUBB	0.0000853	uM	7896.002	1.0570	1.0993	1.1441
MDA-MB-361	HER2amp	Luminal	Taxol	TUBB	TUBB	0.000427	uM	7896.002	1.0200	1.0350	1.1441

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HMS LINCS Project

Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)