Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset - HMS LINCS Database

Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)

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Small molecules	Cells	Antibodies

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Cell	Clinical Subtype	Transcriptional Subtype	Small Molecule	Perturbagen Target	Perturbagen Class	Perturbagen Concentration	Perturbagen Conc Unit	Biological Replicate ID	Relative Cell Count	Normalized Growth Rate Inhibition Value	Nominal Division Rate
MDA-MB-134-VI	HR+	Luminal	Taxol	TUBB	TUBB	1.33	uM	10265.002	0.6964	-0.3175	0.3365
MDA-MB-134-VI	HR+	Luminal	Taxol	TUBB	TUBB	6.67	uM	10265.002	0.7231	-0.2369	0.3365
MDA-MB-134-VI	HR+	Luminal	Taxol	TUBB	TUBB	33.3	uM	10265.002	0.7008	-0.3046	0.3365
MDA-MB-157	TNBC	Basal B	Taxol	TUBB	TUBB	0.0000853	uM	10093.002	0.9615	0.9174	0.9296
MDA-MB-157	TNBC	Basal B	Taxol	TUBB	TUBB	0.000427	uM	10093.002	0.9948	0.9887	0.9296
MDA-MB-157	TNBC	Basal B	Taxol	TUBB	TUBB	0.00213	uM	10093.002	0.9531	0.8993	0.9296
MDA-MB-157	TNBC	Basal B	Taxol	TUBB	TUBB	0.0107	uM	10093.002	0.4268	-0.1998	0.9296
MDA-MB-157	TNBC	Basal B	Taxol	TUBB	TUBB	0.0533	uM	10093.002	0.1924	-0.6604	0.9296
MDA-MB-157	TNBC	Basal B	Taxol	TUBB	TUBB	0.267	uM	10093.002	0.1066	-0.8201	0.9296
MDA-MB-157	TNBC	Basal B	Taxol	TUBB	TUBB	1.33	uM	10093.002	0.1082	-0.8172	0.9296
MDA-MB-157	TNBC	Basal B	Taxol	TUBB	TUBB	6.67	uM	10093.002	0.1262	-0.7842	0.9296
MDA-MB-157	TNBC	Basal B	Taxol	TUBB	TUBB	33.3	uM	10093.002	0.1072	-0.8190	0.9296
MDA-MB-175-VII	HR+	Luminal	Taxol	TUBB	TUBB	0.0000853	uM	7885.002	0.9640	0.8996	0.7110
MDA-MB-175-VII	HR+	Luminal	Taxol	TUBB	TUBB	0.000427	uM	7885.002	0.9873	0.9643	0.7110
MDA-MB-175-VII	HR+	Luminal	Taxol	TUBB	TUBB	0.00213	uM	7885.002	0.9756	0.9316	0.7110
MDA-MB-175-VII	HR+	Luminal	Taxol	TUBB	TUBB	0.0107	uM	7885.002	0.8553	0.6053	0.7110
MDA-MB-175-VII	HR+	Luminal	Taxol	TUBB	TUBB	0.0533	uM	7885.002	0.7701	0.3849	0.7110
MDA-MB-175-VII	HR+	Luminal	Taxol	TUBB	TUBB	0.267	uM	7885.002	0.7180	0.2551	0.7110
MDA-MB-175-VII	HR+	Luminal	Taxol	TUBB	TUBB	1.33	uM	7885.002	0.7547	0.3462	0.7110
MDA-MB-175-VII	HR+	Luminal	Taxol	TUBB	TUBB	6.67	uM	7885.002	0.6857	0.1764	0.7110
MDA-MB-175-VII	HR+	Luminal	Taxol	TUBB	TUBB	33.3	uM	7885.002	0.7251	0.2725	0.7110
MDA-MB-175-VII	HR+	Luminal	Taxol	TUBB	TUBB	0.0000853	uM	7886.002	1.0482	1.1357	0.7173
MDA-MB-175-VII	HR+	Luminal	Taxol	TUBB	TUBB	0.000427	uM	7886.002	1.0034	1.0096	0.7173
MDA-MB-175-VII	HR+	Luminal	Taxol	TUBB	TUBB	0.00213	uM	7886.002	1.0347	1.0974	0.7173
MDA-MB-175-VII	HR+	Luminal	Taxol	TUBB	TUBB	0.0107	uM	7886.002	0.8916	0.7044	0.7173

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HMS LINCS Project

Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)