Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
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HCC2185 | TNBC | Luminal | Taxol | TUBB | TUBB | 33.3 | uM | 9420.002 | 0.6389 | -0.4979 | 0.3242 | |
HCC2185 | TNBC | Luminal | Taxol | TUBB | TUBB | 0.0000853 | uM | 9421.002 | 1.0531 | 1.2037 | 0.5336 | |
HCC2185 | TNBC | Luminal | Taxol | TUBB | TUBB | 0.000427 | uM | 9421.002 | 0.9908 | 0.9655 | 0.5336 | |
HCC2185 | TNBC | Luminal | Taxol | TUBB | TUBB | 0.00213 | uM | 9421.002 | 0.9819 | 0.9328 | 0.5336 | |
HCC2185 | TNBC | Luminal | Taxol | TUBB | TUBB | 0.0107 | uM | 9421.002 | 0.6663 | -0.0655 | 0.5336 | |
HCC2185 | TNBC | Luminal | Taxol | TUBB | TUBB | 0.0533 | uM | 9421.002 | 0.5264 | -0.3991 | 0.5336 | |
HCC2185 | TNBC | Luminal | Taxol | TUBB | TUBB | 0.267 | uM | 9421.002 | 0.5562 | -0.3338 | 0.5336 | |
HCC2185 | TNBC | Luminal | Taxol | TUBB | TUBB | 1.33 | uM | 9421.002 | 0.5672 | -0.3090 | 0.5336 | |
HCC2185 | TNBC | Luminal | Taxol | TUBB | TUBB | 6.67 | uM | 9421.002 | 0.5403 | -0.3690 | 0.5336 | |
HCC2185 | TNBC | Luminal | Taxol | TUBB | TUBB | 33.3 | uM | 9421.002 | 0.5344 | -0.3820 | 0.5336 | |
HCC3153 | TNBC | Basal A | Taxol | TUBB | TUBB | 0.0000853 | uM | 7853.002 | 1.0088 | 1.0060 | 2.9249 | |
HCC3153 | TNBC | Basal A | Taxol | TUBB | TUBB | 0.000427 | uM | 7853.002 | 0.9638 | 0.9750 | 2.9249 | |
HCC3153 | TNBC | Basal A | Taxol | TUBB | TUBB | 0.00213 | uM | 7853.002 | 0.9987 | 0.9991 | 2.9249 | |
HCC3153 | TNBC | Basal A | Taxol | TUBB | TUBB | 0.0107 | uM | 7853.002 | 0.8501 | 0.8920 | 2.9249 | |
HCC3153 | TNBC | Basal A | Taxol | TUBB | TUBB | 0.0533 | uM | 7853.002 | 0.6899 | 0.7617 | 2.9249 | |
HCC3153 | TNBC | Basal A | Taxol | TUBB | TUBB | 0.267 | uM | 7853.002 | 0.5830 | 0.6631 | 2.9249 | |
HCC3153 | TNBC | Basal A | Taxol | TUBB | TUBB | 1.33 | uM | 7853.002 | 0.6175 | 0.6961 | 2.9249 | |
HCC3153 | TNBC | Basal A | Taxol | TUBB | TUBB | 6.67 | uM | 7853.002 | 0.5949 | 0.6746 | 2.9249 | |
HCC3153 | TNBC | Basal A | Taxol | TUBB | TUBB | 33.3 | uM | 7853.002 | 0.5967 | 0.6764 | 2.9249 | |
HCC3153 | TNBC | Basal A | Taxol | TUBB | TUBB | 0.0000853 | uM | 10056.002 | 1.0585 | 1.1345 | 0.8731 | |
HCC3153 | TNBC | Basal A | Taxol | TUBB | TUBB | 0.000427 | uM | 10056.002 | 0.9897 | 0.9763 | 0.8731 | |
HCC3153 | TNBC | Basal A | Taxol | TUBB | TUBB | 0.00213 | uM | 10056.002 | 1.0432 | 1.0993 | 0.8731 | |
HCC3153 | TNBC | Basal A | Taxol | TUBB | TUBB | 0.0107 | uM | 10056.002 | 0.9064 | 0.7871 | 0.8731 | |
HCC3153 | TNBC | Basal A | Taxol | TUBB | TUBB | 0.0533 | uM | 10056.002 | 0.4200 | -0.2595 | 0.8731 | |
HCC3153 | TNBC | Basal A | Taxol | TUBB | TUBB | 0.267 | uM | 10056.002 | 0.3261 | -0.4458 | 0.8731 |