Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC3153 | TNBC | Basal A | Taxol | TUBB | TUBB | 1.33 | uM | 10056.002 | 0.3215 | -0.4547 | 0.8731 | |
| HCC3153 | TNBC | Basal A | Taxol | TUBB | TUBB | 6.67 | uM | 10056.002 | 0.3212 | -0.4554 | 0.8731 | |
| HCC3153 | TNBC | Basal A | Taxol | TUBB | TUBB | 33.3 | uM | 10056.002 | 0.3119 | -0.4734 | 0.8731 | |
| HCC38 | TNBC | Basal B | Taxol | TUBB | TUBB | 0.0000853 | uM | 9453.002 | 0.9741 | 0.9589 | 1.2655 | |
| HCC38 | TNBC | Basal B | Taxol | TUBB | TUBB | 0.000427 | uM | 9453.002 | 0.9370 | 0.8997 | 1.2655 | |
| HCC38 | TNBC | Basal B | Taxol | TUBB | TUBB | 0.00213 | uM | 9453.002 | 0.9411 | 0.9063 | 1.2655 | |
| HCC38 | TNBC | Basal B | Taxol | TUBB | TUBB | 0.0107 | uM | 9453.002 | 0.5263 | 0.2043 | 1.2655 | |
| HCC38 | TNBC | Basal B | Taxol | TUBB | TUBB | 0.0533 | uM | 9453.002 | 0.1854 | -0.4720 | 1.2655 | |
| HCC38 | TNBC | Basal B | Taxol | TUBB | TUBB | 0.267 | uM | 9453.002 | 0.1644 | -0.5199 | 1.2655 | |
| HCC38 | TNBC | Basal B | Taxol | TUBB | TUBB | 1.33 | uM | 9453.002 | 0.1621 | -0.5250 | 1.2655 | |
| HCC38 | TNBC | Basal B | Taxol | TUBB | TUBB | 6.67 | uM | 9453.002 | 0.1477 | -0.5587 | 1.2655 | |
| HCC38 | TNBC | Basal B | Taxol | TUBB | TUBB | 33.3 | uM | 9453.002 | 0.1406 | -0.5756 | 1.2655 | |
| HCC38 | TNBC | Basal B | Taxol | TUBB | TUBB | 0.0000853 | uM | 9469.002 | 0.9604 | 0.9312 | 1.1541 | |
| HCC38 | TNBC | Basal B | Taxol | TUBB | TUBB | 0.000427 | uM | 9469.002 | 1.0140 | 1.0243 | 1.1541 | |
| HCC38 | TNBC | Basal B | Taxol | TUBB | TUBB | 0.00213 | uM | 9469.002 | 0.9659 | 0.9407 | 1.1541 | |
| HCC38 | TNBC | Basal B | Taxol | TUBB | TUBB | 0.0107 | uM | 9469.002 | 0.5339 | 0.1611 | 1.1541 | |
| HCC38 | TNBC | Basal B | Taxol | TUBB | TUBB | 0.0533 | uM | 9469.002 | 0.2079 | -0.4873 | 1.1541 | |
| HCC38 | TNBC | Basal B | Taxol | TUBB | TUBB | 0.267 | uM | 9469.002 | 0.2051 | -0.4932 | 1.1541 | |
| HCC38 | TNBC | Basal B | Taxol | TUBB | TUBB | 1.33 | uM | 9469.002 | 0.2199 | -0.4617 | 1.1541 | |
| HCC38 | TNBC | Basal B | Taxol | TUBB | TUBB | 6.67 | uM | 9469.002 | 0.1847 | -0.5373 | 1.1541 | |
| HCC38 | TNBC | Basal B | Taxol | TUBB | TUBB | 33.3 | uM | 9469.002 | 0.1540 | -0.6045 | 1.1541 | |
| HCC70 | TNBC | Basal A | Taxol | TUBB | TUBB | 0.0000853 | uM | 7857.002 | 1.0416 | 1.0695 | 1.1921 | |
| HCC70 | TNBC | Basal A | Taxol | TUBB | TUBB | 0.000427 | uM | 7857.002 | 1.0056 | 1.0094 | 1.1921 | |
| HCC70 | TNBC | Basal A | Taxol | TUBB | TUBB | 0.00213 | uM | 7857.002 | 1.0039 | 1.0065 | 1.1921 | |
| HCC70 | TNBC | Basal A | Taxol | TUBB | TUBB | 0.0107 | uM | 7857.002 | 0.6423 | 0.3796 | 1.1921 |