Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| T47D | HR+ | Luminal | Temsirolimus | MTOR | MTOR | 0.000341 | uM | 10939.144 | 0.9020 | 0.8831 | 1.7115 | |
| T47D | HR+ | Luminal | Temsirolimus | MTOR | MTOR | 0.00171 | uM | 10939.144 | 0.9169 | 0.9012 | 1.7115 | |
| T47D | HR+ | Luminal | Temsirolimus | MTOR | MTOR | 0.00853 | uM | 10939.144 | 0.8842 | 0.8613 | 1.7115 | |
| T47D | HR+ | Luminal | Temsirolimus | MTOR | MTOR | 0.0427 | uM | 10939.144 | 0.7806 | 0.7306 | 1.7115 | |
| T47D | HR+ | Luminal | Temsirolimus | MTOR | MTOR | 0.213 | uM | 10939.144 | 0.6877 | 0.6071 | 1.7115 | |
| T47D | HR+ | Luminal | Temsirolimus | MTOR | MTOR | 1.07 | uM | 10939.144 | 0.6317 | 0.5293 | 1.7115 | |
| T47D | HR+ | Luminal | Temsirolimus | MTOR | MTOR | 5.33 | uM | 10939.144 | 0.6203 | 0.5130 | 1.7115 | |
| T47D | HR+ | Luminal | Temsirolimus | MTOR | MTOR | 26.7 | uM | 10939.144 | 0.4472 | 0.2498 | 1.7115 | |
| T47D | HR+ | Luminal | Temsirolimus | MTOR | MTOR | 133 | uM | 10939.144 | 0.0174 | -0.8123 | 1.7115 | |
| T47DKBLUC | Unknown | Unknown | Temsirolimus | MTOR | MTOR | 0.000341 | uM | 12608.168 | 0.9936 | 0.9878 | 1.0486 | |
| T47DKBLUC | Unknown | Unknown | Temsirolimus | MTOR | MTOR | 0.00171 | uM | 12608.168 | 0.9524 | 0.9091 | 1.0486 | |
| T47DKBLUC | Unknown | Unknown | Temsirolimus | MTOR | MTOR | 0.00853 | uM | 12608.168 | 0.9512 | 0.9067 | 1.0486 | |
| T47DKBLUC | Unknown | Unknown | Temsirolimus | MTOR | MTOR | 0.0427 | uM | 12608.168 | 0.9909 | 0.9826 | 1.0486 | |
| T47DKBLUC | Unknown | Unknown | Temsirolimus | MTOR | MTOR | 0.213 | uM | 12608.168 | 0.8712 | 0.7536 | 1.0486 | |
| T47DKBLUC | Unknown | Unknown | Temsirolimus | MTOR | MTOR | 1.07 | uM | 12608.168 | 0.8784 | 0.7674 | 1.0486 | |
| T47DKBLUC | Unknown | Unknown | Temsirolimus | MTOR | MTOR | 5.33 | uM | 12608.168 | 0.8420 | 0.6975 | 1.0486 | |
| T47DKBLUC | Unknown | Unknown | Temsirolimus | MTOR | MTOR | 26.7 | uM | 12608.168 | 0.7757 | 0.5697 | 1.0486 | |
| T47DKBLUC | Unknown | Unknown | Temsirolimus | MTOR | MTOR | 133 | uM | 12608.168 | 0.1264 | -0.7218 | 1.0486 | |
| UACC-812 | HER2amp | Luminal | Temsirolimus | MTOR | MTOR | 0.000341 | uM | 10580.144 | 0.8531 | 0.6605 | 0.8541 | |
| UACC-812 | HER2amp | Luminal | Temsirolimus | MTOR | MTOR | 0.00171 | uM | 10580.144 | 0.7766 | 0.4875 | 0.8541 | |
| UACC-812 | HER2amp | Luminal | Temsirolimus | MTOR | MTOR | 0.00853 | uM | 10580.144 | 0.6925 | 0.3007 | 0.8541 | |
| UACC-812 | HER2amp | Luminal | Temsirolimus | MTOR | MTOR | 0.0427 | uM | 10580.144 | 0.7741 | 0.4820 | 0.8541 | |
| UACC-812 | HER2amp | Luminal | Temsirolimus | MTOR | MTOR | 0.213 | uM | 10580.144 | 0.7376 | 0.4006 | 0.8541 | |
| UACC-812 | HER2amp | Luminal | Temsirolimus | MTOR | MTOR | 1.07 | uM | 10580.144 | 0.6605 | 0.2306 | 0.8541 | |
| UACC-812 | HER2amp | Luminal | Temsirolimus | MTOR | MTOR | 5.33 | uM | 10580.144 | 0.6814 | 0.2763 | 0.8541 |