Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| UACC-812 | HER2amp | Luminal | Temsirolimus | MTOR | MTOR | 26.7 | uM | 10580.144 | 0.5634 | 0.0216 | 0.8541 | |
| UACC-812 | HER2amp | Luminal | Temsirolimus | MTOR | MTOR | 133 | uM | 10580.144 | 0.0376 | -0.9570 | 0.8541 | |
| UACC-812 | HER2amp | Luminal | Temsirolimus | MTOR | MTOR | 0.000341 | uM | 10754.144 | 1.0425 | 1.1017 | 0.8390 | |
| UACC-812 | HER2amp | Luminal | Temsirolimus | MTOR | MTOR | 0.00171 | uM | 10754.144 | 0.9284 | 0.8305 | 0.8390 | |
| UACC-812 | HER2amp | Luminal | Temsirolimus | MTOR | MTOR | 0.00853 | uM | 10754.144 | 0.8774 | 0.7113 | 0.8390 | |
| UACC-812 | HER2amp | Luminal | Temsirolimus | MTOR | MTOR | 0.0427 | uM | 10754.144 | 0.8932 | 0.7480 | 0.8390 | |
| UACC-812 | HER2amp | Luminal | Temsirolimus | MTOR | MTOR | 0.213 | uM | 10754.144 | 0.8325 | 0.6074 | 0.8390 | |
| UACC-812 | HER2amp | Luminal | Temsirolimus | MTOR | MTOR | 1.07 | uM | 10754.144 | 0.6625 | 0.2244 | 0.8390 | |
| UACC-812 | HER2amp | Luminal | Temsirolimus | MTOR | MTOR | 5.33 | uM | 10754.144 | 0.5867 | 0.0592 | 0.8390 | |
| UACC-812 | HER2amp | Luminal | Temsirolimus | MTOR | MTOR | 26.7 | uM | 10754.144 | 0.4058 | -0.3174 | 0.8390 | |
| UACC-812 | HER2amp | Luminal | Temsirolimus | MTOR | MTOR | 133 | uM | 10754.144 | 0.0033 | -0.9978 | 0.8390 | |
| UACC-812 | HER2amp | Luminal | Temsirolimus | MTOR | MTOR | 0.000341 | uM | 11938.144 | 0.8859 | 0.6571 | 0.6445 | |
| UACC-812 | HER2amp | Luminal | Temsirolimus | MTOR | MTOR | 0.00171 | uM | 11938.144 | 0.8427 | 0.5335 | 0.6445 | |
| UACC-812 | HER2amp | Luminal | Temsirolimus | MTOR | MTOR | 0.00853 | uM | 11938.144 | 0.9327 | 0.7949 | 0.6445 | |
| UACC-812 | HER2amp | Luminal | Temsirolimus | MTOR | MTOR | 0.0427 | uM | 11938.144 | 0.9015 | 0.7029 | 0.6445 | |
| UACC-812 | HER2amp | Luminal | Temsirolimus | MTOR | MTOR | 0.213 | uM | 11938.144 | 0.7607 | 0.3082 | 0.6445 | |
| UACC-812 | HER2amp | Luminal | Temsirolimus | MTOR | MTOR | 1.07 | uM | 11938.144 | 0.6803 | 0.1002 | 0.6445 | |
| UACC-812 | HER2amp | Luminal | Temsirolimus | MTOR | MTOR | 5.33 | uM | 11938.144 | 0.7045 | 0.1614 | 0.6445 | |
| UACC-812 | HER2amp | Luminal | Temsirolimus | MTOR | MTOR | 26.7 | uM | 11938.144 | 0.6174 | -0.0537 | 0.6445 | |
| UACC-812 | HER2amp | Luminal | Temsirolimus | MTOR | MTOR | 133 | uM | 11938.144 | 0.4629 | -0.3947 | 0.6445 | |
| ZR-75-1 | HR+ | Luminal | Temsirolimus | MTOR | MTOR | 0.000341 | uM | 11660.144 | 0.7947 | 0.5993 | 1.0279 | |
| ZR-75-1 | HR+ | Luminal | Temsirolimus | MTOR | MTOR | 0.00171 | uM | 11660.144 | 0.6678 | 0.3503 | 1.0279 | |
| ZR-75-1 | HR+ | Luminal | Temsirolimus | MTOR | MTOR | 0.00853 | uM | 11660.144 | 0.6303 | 0.2765 | 1.0279 | |
| ZR-75-1 | HR+ | Luminal | Temsirolimus | MTOR | MTOR | 0.0427 | uM | 11660.144 | 0.7028 | 0.4191 | 1.0279 | |
| ZR-75-1 | HR+ | Luminal | Temsirolimus | MTOR | MTOR | 0.213 | uM | 11660.144 | 0.6444 | 0.3042 | 1.0279 |