Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset - HMS LINCS Database

Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)

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Small molecules	Cells	Antibodies

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Cell	Clinical Subtype	Transcriptional Subtype	Small Molecule	Perturbagen Target	Perturbagen Class	Perturbagen Concentration	Perturbagen Conc Unit	Biological Replicate ID	Relative Cell Count	Normalized Growth Rate Inhibition Value	Nominal Division Rate
MDA-MB-157	TNBC	Basal B	Temsirolimus	MTOR	MTOR	0.000341	uM	12594.168	0.9737	0.9585	1.2703
MDA-MB-157	TNBC	Basal B	Temsirolimus	MTOR	MTOR	0.00171	uM	12594.168	1.0478	1.0748	1.2703
MDA-MB-157	TNBC	Basal B	Temsirolimus	MTOR	MTOR	0.00853	uM	12594.168	0.9943	0.9910	1.2703
MDA-MB-157	TNBC	Basal B	Temsirolimus	MTOR	MTOR	0.0427	uM	12594.168	0.8913	0.8267	1.2703
MDA-MB-157	TNBC	Basal B	Temsirolimus	MTOR	MTOR	0.213	uM	12594.168	0.8952	0.8331	1.2703
MDA-MB-157	TNBC	Basal B	Temsirolimus	MTOR	MTOR	1.07	uM	12594.168	0.8268	0.7218	1.2703
MDA-MB-157	TNBC	Basal B	Temsirolimus	MTOR	MTOR	5.33	uM	12594.168	0.8379	0.7400	1.2703
MDA-MB-157	TNBC	Basal B	Temsirolimus	MTOR	MTOR	26.7	uM	12594.168	0.6958	0.5032	1.2703
MDA-MB-157	TNBC	Basal B	Temsirolimus	MTOR	MTOR	133	uM	12594.168	0.0077	-0.9566	1.2703
MDA-MB-175-VII	HR+	Luminal	Temsirolimus	MTOR	MTOR	0.000341	uM	10642.144	0.7739	0.3492	0.6510
MDA-MB-175-VII	HR+	Luminal	Temsirolimus	MTOR	MTOR	0.00171	uM	10642.144	0.6588	0.0534	0.6510
MDA-MB-175-VII	HR+	Luminal	Temsirolimus	MTOR	MTOR	0.00853	uM	10642.144	0.6632	0.0643	0.6510
MDA-MB-175-VII	HR+	Luminal	Temsirolimus	MTOR	MTOR	0.0427	uM	10642.144	0.6227	-0.0338	0.6510
MDA-MB-175-VII	HR+	Luminal	Temsirolimus	MTOR	MTOR	0.213	uM	10642.144	0.6868	0.1229	0.6510
MDA-MB-175-VII	HR+	Luminal	Temsirolimus	MTOR	MTOR	1.07	uM	10642.144	0.6663	0.0720	0.6510
MDA-MB-175-VII	HR+	Luminal	Temsirolimus	MTOR	MTOR	5.33	uM	10642.144	0.6599	0.0561	0.6510
MDA-MB-175-VII	HR+	Luminal	Temsirolimus	MTOR	MTOR	26.7	uM	10642.144	0.6663	0.0719	0.6510
MDA-MB-175-VII	HR+	Luminal	Temsirolimus	MTOR	MTOR	133	uM	10642.144	0.0329	-0.9895	0.6510
MDA-MB-175-VII	HR+	Luminal	Temsirolimus	MTOR	MTOR	0.000341	uM	10818.144	0.9440	0.7787	0.4912
MDA-MB-175-VII	HR+	Luminal	Temsirolimus	MTOR	MTOR	0.00171	uM	10818.144	0.8813	0.5462	0.4912
MDA-MB-175-VII	HR+	Luminal	Temsirolimus	MTOR	MTOR	0.00853	uM	10818.144	0.8510	0.4400	0.4912
MDA-MB-175-VII	HR+	Luminal	Temsirolimus	MTOR	MTOR	0.0427	uM	10818.144	0.8109	0.3053	0.4912
MDA-MB-175-VII	HR+	Luminal	Temsirolimus	MTOR	MTOR	0.213	uM	10818.144	0.8109	0.3051	0.4912
MDA-MB-175-VII	HR+	Luminal	Temsirolimus	MTOR	MTOR	1.07	uM	10818.144	0.7653	0.1601	0.4912
MDA-MB-175-VII	HR+	Luminal	Temsirolimus	MTOR	MTOR	5.33	uM	10818.144	0.7844	0.2197	0.4912

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HMS LINCS Project

Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)