Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC70 | TNBC | Basal A | Taxol | TUBB | TUBB | 0.0533 | uM | 7857.002 | 0.2509 | -0.3731 | 1.1921 | |
| HCC70 | TNBC | Basal A | Taxol | TUBB | TUBB | 0.267 | uM | 7857.002 | 0.1981 | -0.4858 | 1.1921 | |
| HCC70 | TNBC | Basal A | Taxol | TUBB | TUBB | 1.33 | uM | 7857.002 | 0.2360 | -0.4043 | 1.1921 | |
| HCC70 | TNBC | Basal A | Taxol | TUBB | TUBB | 6.67 | uM | 7857.002 | 0.2504 | -0.3740 | 1.1921 | |
| HCC70 | TNBC | Basal A | Taxol | TUBB | TUBB | 33.3 | uM | 7857.002 | 0.2287 | -0.4198 | 1.1921 | |
| HCC70 | TNBC | Basal A | Taxol | TUBB | TUBB | 0.0000853 | uM | 9501.002 | 1.0038 | 1.0076 | 1.0082 | |
| HCC70 | TNBC | Basal A | Taxol | TUBB | TUBB | 0.000427 | uM | 9501.002 | 0.9934 | 0.9869 | 1.0082 | |
| HCC70 | TNBC | Basal A | Taxol | TUBB | TUBB | 0.00213 | uM | 9501.002 | 0.9605 | 0.9215 | 1.0082 | |
| HCC70 | TNBC | Basal A | Taxol | TUBB | TUBB | 0.0107 | uM | 9501.002 | 0.6243 | 0.2534 | 1.0082 | |
| HCC70 | TNBC | Basal A | Taxol | TUBB | TUBB | 0.0533 | uM | 9501.002 | 0.2578 | -0.4787 | 1.0082 | |
| HCC70 | TNBC | Basal A | Taxol | TUBB | TUBB | 0.267 | uM | 9501.002 | 0.1805 | -0.6340 | 1.0082 | |
| HCC70 | TNBC | Basal A | Taxol | TUBB | TUBB | 1.33 | uM | 9501.002 | 0.1899 | -0.6150 | 1.0082 | |
| HCC70 | TNBC | Basal A | Taxol | TUBB | TUBB | 6.67 | uM | 9501.002 | 0.1570 | -0.6813 | 1.0082 | |
| HCC70 | TNBC | Basal A | Taxol | TUBB | TUBB | 33.3 | uM | 9501.002 | 0.1907 | -0.6134 | 1.0082 | |
| HCC70 | TNBC | Basal A | Taxol | TUBB | TUBB | 0.0000853 | uM | 12714.002 | 1.0879 | 1.4298 | 0.4328 | |
| HCC70 | TNBC | Basal A | Taxol | TUBB | TUBB | 0.000427 | uM | 12714.002 | 1.0013 | 1.0062 | 0.4328 | |
| HCC70 | TNBC | Basal A | Taxol | TUBB | TUBB | 0.00213 | uM | 12714.002 | 1.0665 | 1.3207 | 0.4328 | |
| HCC70 | TNBC | Basal A | Taxol | TUBB | TUBB | 0.0107 | uM | 12714.002 | 0.7404 | -0.0013 | 0.4328 | |
| HCC70 | TNBC | Basal A | Taxol | TUBB | TUBB | 0.0533 | uM | 12714.002 | 0.2938 | -0.8820 | 0.4328 | |
| HCC70 | TNBC | Basal A | Taxol | TUBB | TUBB | 0.267 | uM | 12714.002 | 0.2797 | -0.8947 | 0.4328 | |
| HCC70 | TNBC | Basal A | Taxol | TUBB | TUBB | 1.33 | uM | 12714.002 | 0.2424 | -0.9243 | 0.4328 | |
| HCC70 | TNBC | Basal A | Taxol | TUBB | TUBB | 6.67 | uM | 12714.002 | 0.2552 | -0.9148 | 0.4328 | |
| HCC70 | TNBC | Basal A | Taxol | TUBB | TUBB | 33.3 | uM | 12714.002 | 0.2633 | -0.9084 | 0.4328 | |
| HMT-3522 S1 | Unknown | Unknown | Taxol | TUBB | TUBB | 0.0000853 | uM | 10124.002 | 1.1989 | 1.1823 | 2.0795 | |
| HMT-3522 S1 | Unknown | Unknown | Taxol | TUBB | TUBB | 0.000427 | uM | 10124.002 | 0.9988 | 0.9988 | 2.0795 |