Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1187 | TNBC | Basal A | Taxol | TUBB | TUBB | 1.33 | uM | 9244.002 | 0.0450 | -0.9948 | 0.5206 | |
| HCC1187 | TNBC | Basal A | Taxol | TUBB | TUBB | 6.67 | uM | 9244.002 | 0.0349 | -0.9968 | 0.5206 | |
| HCC1187 | TNBC | Basal A | Taxol | TUBB | TUBB | 33.3 | uM | 9244.002 | 0.0496 | -0.9938 | 0.5206 | |
| HCC1187 | TNBC | Basal A | Taxol | TUBB | TUBB | 0.0000853 | uM | 12696.002 | 1.0162 | 1.0452 | 0.7184 | |
| HCC1187 | TNBC | Basal A | Taxol | TUBB | TUBB | 0.000427 | uM | 12696.002 | 0.9305 | 0.8091 | 0.7184 | |
| HCC1187 | TNBC | Basal A | Taxol | TUBB | TUBB | 0.00213 | uM | 12696.002 | 1.0121 | 1.0339 | 0.7184 | |
| HCC1187 | TNBC | Basal A | Taxol | TUBB | TUBB | 0.0107 | uM | 12696.002 | 0.5343 | -0.1642 | 0.7184 | |
| HCC1187 | TNBC | Basal A | Taxol | TUBB | TUBB | 0.0533 | uM | 12696.002 | 0.0464 | -0.9721 | 0.7184 | |
| HCC1187 | TNBC | Basal A | Taxol | TUBB | TUBB | 0.267 | uM | 12696.002 | 0.0421 | -0.9757 | 0.7184 | |
| HCC1187 | TNBC | Basal A | Taxol | TUBB | TUBB | 1.33 | uM | 12696.002 | 0.0375 | -0.9793 | 0.7184 | |
| HCC1187 | TNBC | Basal A | Taxol | TUBB | TUBB | 6.67 | uM | 12696.002 | 0.0474 | -0.9713 | 0.7184 | |
| HCC1187 | TNBC | Basal A | Taxol | TUBB | TUBB | 33.3 | uM | 12696.002 | 0.0526 | -0.9669 | 0.7184 | |
| HCC1395 | TNBC | Basal B | Taxol | TUBB | TUBB | 0.0000853 | uM | 7813.002 | 1.1501 | 1.3593 | 0.8463 | |
| HCC1395 | TNBC | Basal B | Taxol | TUBB | TUBB | 0.000427 | uM | 7813.002 | 0.7887 | 0.5109 | 0.8463 | |
| HCC1395 | TNBC | Basal B | Taxol | TUBB | TUBB | 0.00213 | uM | 7813.002 | 1.0949 | 1.2261 | 0.8463 | |
| HCC1395 | TNBC | Basal B | Taxol | TUBB | TUBB | 0.0107 | uM | 7813.002 | 0.8930 | 0.7497 | 0.8463 | |
| HCC1395 | TNBC | Basal B | Taxol | TUBB | TUBB | 0.0533 | uM | 7813.002 | 0.4697 | -0.1810 | 0.8463 | |
| HCC1395 | TNBC | Basal B | Taxol | TUBB | TUBB | 0.267 | uM | 7813.002 | 0.3459 | -0.4295 | 0.8463 | |
| HCC1395 | TNBC | Basal B | Taxol | TUBB | TUBB | 1.33 | uM | 7813.002 | 0.3486 | -0.4242 | 0.8463 | |
| HCC1395 | TNBC | Basal B | Taxol | TUBB | TUBB | 6.67 | uM | 7813.002 | 0.3176 | -0.4841 | 0.8463 | |
| HCC1395 | TNBC | Basal B | Taxol | TUBB | TUBB | 33.3 | uM | 7813.002 | 0.3560 | -0.4098 | 0.8463 | |
| HCC1395 | TNBC | Basal B | Taxol | TUBB | TUBB | 0.0000853 | uM | 9254.002 | 1.1698 | 1.9647 | 0.3983 | |
| HCC1395 | TNBC | Basal B | Taxol | TUBB | TUBB | 0.000427 | uM | 9254.002 | 1.1348 | 1.7472 | 0.3983 | |
| HCC1395 | TNBC | Basal B | Taxol | TUBB | TUBB | 0.00213 | uM | 9254.002 | 1.2569 | 2.5506 | 0.3983 | |
| HCC1395 | TNBC | Basal B | Taxol | TUBB | TUBB | 0.0107 | uM | 9254.002 | 1.0062 | 1.0311 | 0.3983 |