Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Hs 578T | TNBC | Basal B | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 0.000427 | uM | 7475.067 | 0.9501 | 0.9580 | 2.4078 | |
| Hs 578T | TNBC | Basal B | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 0.00213 | uM | 7475.067 | 1.0026 | 1.0022 | 2.4078 | |
| Hs 578T | TNBC | Basal B | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 0.0107 | uM | 7475.067 | 0.9231 | 0.9346 | 2.4078 | |
| Hs 578T | TNBC | Basal B | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 0.0533 | uM | 7475.067 | 1.1050 | 1.0847 | 2.4078 | |
| Hs 578T | TNBC | Basal B | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 0.267 | uM | 7475.067 | 0.9531 | 0.9605 | 2.4078 | |
| Hs 578T | TNBC | Basal B | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 1.33 | uM | 7475.067 | 0.9775 | 0.9812 | 2.4078 | |
| Hs 578T | TNBC | Basal B | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 6.67 | uM | 7475.067 | 0.2953 | 0.2051 | 2.4078 | |
| Hs 578T | TNBC | Basal B | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 33.3 | uM | 7475.067 | 0.0011 | -0.8808 | 2.4078 | |
| Hs 578T | TNBC | Basal B | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 167 | uM | 7475.067 | 0.0011 | -0.8808 | 2.4078 | |
| LY2 | HR+ | Luminal | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 0.000427 | uM | 7477.067 | 1.6257 | 3.0924 | 0.6787 | |
| LY2 | HR+ | Luminal | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 0.00213 | uM | 7477.067 | 1.5351 | 2.7607 | 0.6787 | |
| LY2 | HR+ | Luminal | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 0.0107 | uM | 7477.067 | 1.2637 | 1.8233 | 0.6787 | |
| LY2 | HR+ | Luminal | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 0.0533 | uM | 7477.067 | 1.4817 | 2.5697 | 0.6787 | |
| LY2 | HR+ | Luminal | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 0.267 | uM | 7477.067 | 0.9871 | 0.9620 | 0.6787 | |
| LY2 | HR+ | Luminal | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 1.33 | uM | 7477.067 | 1.5900 | 2.9605 | 0.6787 | |
| LY2 | HR+ | Luminal | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 6.67 | uM | 7477.067 | 0.7451 | 0.2966 | 0.6787 | |
| LY2 | HR+ | Luminal | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 33.3 | uM | 7477.067 | 0.0016 | -0.9999 | 0.6787 | |
| LY2 | HR+ | Luminal | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 167 | uM | 7477.067 | 0.0016 | -0.9999 | 0.6787 | |
| MB 157 | Unknown | Unknown | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 0.000427 | uM | 7482.067 | 0.8604 | 0.8505 | 1.9350 | |
| MB 157 | Unknown | Unknown | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 0.00213 | uM | 7482.067 | 0.8907 | 0.8838 | 1.9350 | |
| MB 157 | Unknown | Unknown | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 0.0107 | uM | 7482.067 | 0.8439 | 0.8321 | 1.9350 | |
| MB 157 | Unknown | Unknown | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 0.0533 | uM | 7482.067 | 0.9944 | 0.9942 | 1.9350 | |
| MB 157 | Unknown | Unknown | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 0.267 | uM | 7482.067 | 0.9775 | 0.9766 | 1.9350 | |
| MB 157 | Unknown | Unknown | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 1.33 | uM | 7482.067 | 0.6334 | 0.5795 | 1.9350 | |
| MB 157 | Unknown | Unknown | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 6.67 | uM | 7482.067 | 0.4677 | 0.3504 | 1.9350 |