Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MB 157 | Unknown | Unknown | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 33.3 | uM | 7482.067 | 0.0079 | -0.8363 | 1.9350 | |
| MB 157 | Unknown | Unknown | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 167 | uM | 7482.067 | 0.0008 | -0.9514 | 1.9350 | |
| MCF 10A | NM | Basal B | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 0.000427 | uM | 7483.067 | 1.0048 | 1.0029 | 3.2893 | |
| MCF 10A | NM | Basal B | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 0.00213 | uM | 7483.067 | 1.0780 | 1.0462 | 3.2893 | |
| MCF 10A | NM | Basal B | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 0.0107 | uM | 7483.067 | 0.9619 | 0.9765 | 3.2893 | |
| MCF 10A | NM | Basal B | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 0.0533 | uM | 7483.067 | 1.0298 | 1.0179 | 3.2893 | |
| MCF 10A | NM | Basal B | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 0.267 | uM | 7483.067 | 0.9808 | 0.9883 | 3.2893 | |
| MCF 10A | NM | Basal B | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 1.33 | uM | 7483.067 | 0.9769 | 0.9859 | 3.2893 | |
| MCF 10A | NM | Basal B | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 6.67 | uM | 7483.067 | 0.4369 | 0.5549 | 3.2893 | |
| MCF 10A | NM | Basal B | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 33.3 | uM | 7483.067 | 0.0117 | -0.4833 | 3.2893 | |
| MCF 10A | NM | Basal B | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 167 | uM | 7483.067 | 0.0014 | -0.7295 | 3.2893 | |
| MCF 10A | NM | Basal B | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 0.000427 | uM | 7484.067 | 0.9421 | 0.9564 | 2.7060 | |
| MCF 10A | NM | Basal B | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 0.00213 | uM | 7484.067 | 1.0032 | 1.0024 | 2.7060 | |
| MCF 10A | NM | Basal B | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 0.0107 | uM | 7484.067 | 0.9138 | 0.9345 | 2.7060 | |
| MCF 10A | NM | Basal B | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 0.0533 | uM | 7484.067 | 0.9472 | 0.9603 | 2.7060 | |
| MCF 10A | NM | Basal B | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 0.267 | uM | 7484.067 | 0.9719 | 0.9790 | 2.7060 | |
| MCF 10A | NM | Basal B | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 1.33 | uM | 7484.067 | 0.9158 | 0.9360 | 2.7060 | |
| MCF 10A | NM | Basal B | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 6.67 | uM | 7484.067 | 0.4608 | 0.5021 | 2.7060 | |
| MCF 10A | NM | Basal B | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 33.3 | uM | 7484.067 | 0.0090 | -0.6486 | 2.7060 | |
| MCF 10A | NM | Basal B | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 167 | uM | 7484.067 | 0.0033 | -0.7590 | 2.7060 | |
| MCF 10A | NM | Basal B | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 0.000427 | uM | 7485.067 | 0.9607 | 0.9788 | 3.7597 | |
| MCF 10A | NM | Basal B | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 0.00213 | uM | 7485.067 | 0.9099 | 0.9504 | 3.7597 | |
| MCF 10A | NM | Basal B | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 0.0107 | uM | 7485.067 | 0.9395 | 0.9671 | 3.7597 | |
| MCF 10A | NM | Basal B | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 0.0533 | uM | 7485.067 | 0.9474 | 0.9715 | 3.7597 | |
| MCF 10A | NM | Basal B | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 0.267 | uM | 7485.067 | 0.9352 | 0.9647 | 3.7597 |