Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset - HMS LINCS Database

Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)

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Small molecules	Cells	Antibodies

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Cell	Clinical Subtype	Transcriptional Subtype	Small Molecule	Perturbagen Target	Perturbagen Class	Perturbagen Concentration	Perturbagen Conc Unit	Biological Replicate ID	Relative Cell Count	Normalized Growth Rate Inhibition Value	Nominal Division Rate
SUM1315MO2	TNBC	Basal B	Sigma A6730	AKT	AKT	0.000171	uM	10875.153	0.9803	0.9536	0.8455
SUM1315MO2	TNBC	Basal B	Sigma A6730	AKT	AKT	0.000853	uM	10875.153	1.0557	1.1324	0.8455
SUM1315MO2	TNBC	Basal B	Sigma A6730	AKT	AKT	0.00427	uM	10875.153	1.0079	1.0187	0.8455
SUM1315MO2	TNBC	Basal B	Sigma A6730	AKT	AKT	0.0213	uM	10875.153	0.9454	0.8714	0.8455
SUM1315MO2	TNBC	Basal B	Sigma A6730	AKT	AKT	0.107	uM	10875.153	0.9957	0.9898	0.8455
SUM1315MO2	TNBC	Basal B	Sigma A6730	AKT	AKT	0.533	uM	10875.153	0.8990	0.7633	0.8455
SUM1315MO2	TNBC	Basal B	Sigma A6730	AKT	AKT	2.67	uM	10875.153	0.8403	0.6279	0.8455
SUM1315MO2	TNBC	Basal B	Sigma A6730	AKT	AKT	13.3	uM	10875.153	0.4431	-0.2363	0.8455
SUM1315MO2	TNBC	Basal B	Sigma A6730	AKT	AKT	66.7	uM	10875.153	0.0127	-0.9886	0.8455
SUM1315MO2	TNBC	Basal B	Sigma A6730	AKT	AKT	0.000171	uM	12428.165	0.9985	0.9958	0.7051
SUM1315MO2	TNBC	Basal B	Sigma A6730	AKT	AKT	0.000853	uM	12428.165	1.0179	1.0511	0.7051
SUM1315MO2	TNBC	Basal B	Sigma A6730	AKT	AKT	0.00427	uM	12428.165	0.9870	0.9631	0.7051
SUM1315MO2	TNBC	Basal B	Sigma A6730	AKT	AKT	0.0213	uM	12428.165	0.9788	0.9401	0.7051
SUM1315MO2	TNBC	Basal B	Sigma A6730	AKT	AKT	0.107	uM	12428.165	0.9813	0.9471	0.7051
SUM1315MO2	TNBC	Basal B	Sigma A6730	AKT	AKT	0.533	uM	12428.165	0.9726	0.9228	0.7051
SUM1315MO2	TNBC	Basal B	Sigma A6730	AKT	AKT	2.67	uM	12428.165	0.8602	0.6153	0.7051
SUM1315MO2	TNBC	Basal B	Sigma A6730	AKT	AKT	13.3	uM	12428.165	0.6157	0.0053	0.7051
SUM1315MO2	TNBC	Basal B	Sigma A6730	AKT	AKT	66.7	uM	12428.165	0.0088	-0.9976	0.7051
SUM149PT	TNBC	Basal B	Sigma A6730	AKT	AKT	0.000171	uM	10819.153	0.9694	0.9702	2.0690
SUM149PT	TNBC	Basal B	Sigma A6730	AKT	AKT	0.000853	uM	10819.153	0.9704	0.9711	2.0690
SUM149PT	TNBC	Basal B	Sigma A6730	AKT	AKT	0.00427	uM	10819.153	0.9663	0.9671	2.0690
SUM149PT	TNBC	Basal B	Sigma A6730	AKT	AKT	0.0213	uM	10819.153	1.0341	1.0327	2.0690
SUM149PT	TNBC	Basal B	Sigma A6730	AKT	AKT	0.107	uM	10819.153	0.9826	0.9831	2.0690
SUM149PT	TNBC	Basal B	Sigma A6730	AKT	AKT	0.533	uM	10819.153	0.9785	0.9791	2.0690
SUM149PT	TNBC	Basal B	Sigma A6730	AKT	AKT	2.67	uM	10819.153	0.9317	0.9327	2.0690

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HMS LINCS Project

Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)