Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SUM149PT | TNBC | Basal B | Sigma A6730 | AKT | AKT | 13.3 | uM | 10819.153 | 0.5259 | 0.4660 | 2.0690 | |
| SUM149PT | TNBC | Basal B | Sigma A6730 | AKT | AKT | 66.7 | uM | 10819.153 | 0.0812 | -0.4057 | 2.0690 | |
| SUM149PT | TNBC | Basal B | Sigma A6730 | AKT | AKT | 0.000171 | uM | 11937.158 | 0.9349 | 0.9408 | 2.2386 | |
| SUM149PT | TNBC | Basal B | Sigma A6730 | AKT | AKT | 0.000853 | uM | 11937.158 | 0.9629 | 0.9665 | 2.2386 | |
| SUM149PT | TNBC | Basal B | Sigma A6730 | AKT | AKT | 0.00427 | uM | 11937.158 | 1.0279 | 1.0247 | 2.2386 | |
| SUM149PT | TNBC | Basal B | Sigma A6730 | AKT | AKT | 0.0213 | uM | 11937.158 | 0.9567 | 0.9609 | 2.2386 | |
| SUM149PT | TNBC | Basal B | Sigma A6730 | AKT | AKT | 0.107 | uM | 11937.158 | 1.0153 | 1.0136 | 2.2386 | |
| SUM149PT | TNBC | Basal B | Sigma A6730 | AKT | AKT | 0.533 | uM | 11937.158 | 0.9249 | 0.9315 | 2.2386 | |
| SUM149PT | TNBC | Basal B | Sigma A6730 | AKT | AKT | 2.67 | uM | 11937.158 | 0.8780 | 0.8870 | 2.2386 | |
| SUM149PT | TNBC | Basal B | Sigma A6730 | AKT | AKT | 13.3 | uM | 11937.158 | 0.3534 | 0.2568 | 2.2386 | |
| SUM149PT | TNBC | Basal B | Sigma A6730 | AKT | AKT | 66.7 | uM | 11937.158 | 0.0010 | -0.9092 | 2.2386 | |
| SUM159PT | TNBC | Basal B | Sigma A6730 | AKT | AKT | 0.000171 | uM | 10520.141 | 0.8174 | 0.8922 | 3.6374 | |
| SUM159PT | TNBC | Basal B | Sigma A6730 | AKT | AKT | 0.000853 | uM | 10520.141 | 1.0067 | 1.0037 | 3.6374 | |
| SUM159PT | TNBC | Basal B | Sigma A6730 | AKT | AKT | 0.00427 | uM | 10520.141 | 1.0204 | 1.0111 | 3.6374 | |
| SUM159PT | TNBC | Basal B | Sigma A6730 | AKT | AKT | 0.0213 | uM | 10520.141 | 0.9726 | 0.9848 | 3.6374 | |
| SUM159PT | TNBC | Basal B | Sigma A6730 | AKT | AKT | 0.107 | uM | 10520.141 | 1.0114 | 1.0062 | 3.6374 | |
| SUM159PT | TNBC | Basal B | Sigma A6730 | AKT | AKT | 0.533 | uM | 10520.141 | 0.9488 | 0.9713 | 3.6374 | |
| SUM159PT | TNBC | Basal B | Sigma A6730 | AKT | AKT | 2.67 | uM | 10520.141 | 0.9022 | 0.9442 | 3.6374 | |
| SUM159PT | TNBC | Basal B | Sigma A6730 | AKT | AKT | 13.3 | uM | 10520.141 | 0.2578 | 0.3778 | 3.6374 | |
| SUM159PT | TNBC | Basal B | Sigma A6730 | AKT | AKT | 66.7 | uM | 10520.141 | 0.0009 | -0.7115 | 3.6374 | |
| SUM159PT | TNBC | Basal B | Sigma A6730 | AKT | AKT | 0.000171 | uM | 11057.158 | 0.9295 | 0.9625 | 3.8594 | |
| SUM159PT | TNBC | Basal B | Sigma A6730 | AKT | AKT | 0.000853 | uM | 11057.158 | 1.0397 | 1.0203 | 3.8594 | |
| SUM159PT | TNBC | Basal B | Sigma A6730 | AKT | AKT | 0.00427 | uM | 11057.158 | 0.9804 | 0.9898 | 3.8594 | |
| SUM159PT | TNBC | Basal B | Sigma A6730 | AKT | AKT | 0.0213 | uM | 11057.158 | 1.0246 | 1.0126 | 3.8594 | |
| SUM159PT | TNBC | Basal B | Sigma A6730 | AKT | AKT | 0.107 | uM | 11057.158 | 0.9829 | 0.9911 | 3.8594 |