Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1428 | HR+ | Luminal | SB-3CT | MMP2/9 | MMP | 0.8 | uM | 10693.144 | 0.9857 | 0.9666 | 0.8585 | |
| HCC1428 | HR+ | Luminal | SB-3CT | MMP2/9 | MMP | 4 | uM | 10693.144 | 0.9858 | 0.9668 | 0.8585 | |
| HCC1428 | HR+ | Luminal | SB-3CT | MMP2/9 | MMP | 20 | uM | 10693.144 | 0.8878 | 0.7411 | 0.8585 | |
| HCC1428 | HR+ | Luminal | SB-3CT | MMP2/9 | MMP | 100 | uM | 10693.144 | 0.3607 | -0.3902 | 0.8585 | |
| HCC1428 | HR+ | Luminal | SB-3CT | MMP2/9 | MMP | 0.000256 | uM | 11936.144 | 0.9796 | 0.9540 | 0.8864 | |
| HCC1428 | HR+ | Luminal | SB-3CT | MMP2/9 | MMP | 0.00128 | uM | 11936.144 | 0.9408 | 0.8668 | 0.8864 | |
| HCC1428 | HR+ | Luminal | SB-3CT | MMP2/9 | MMP | 0.0064 | uM | 11936.144 | 0.9675 | 0.9268 | 0.8864 | |
| HCC1428 | HR+ | Luminal | SB-3CT | MMP2/9 | MMP | 0.032 | uM | 11936.144 | 0.9656 | 0.9225 | 0.8864 | |
| HCC1428 | HR+ | Luminal | SB-3CT | MMP2/9 | MMP | 0.16 | uM | 11936.144 | 0.9527 | 0.8936 | 0.8864 | |
| HCC1428 | HR+ | Luminal | SB-3CT | MMP2/9 | MMP | 0.8 | uM | 11936.144 | 1.0069 | 1.0156 | 0.8864 | |
| HCC1428 | HR+ | Luminal | SB-3CT | MMP2/9 | MMP | 4 | uM | 11936.144 | 0.9277 | 0.8376 | 0.8864 | |
| HCC1428 | HR+ | Luminal | SB-3CT | MMP2/9 | MMP | 20 | uM | 11936.144 | 0.9233 | 0.8277 | 0.8864 | |
| HCC1428 | HR+ | Luminal | SB-3CT | MMP2/9 | MMP | 100 | uM | 11936.144 | 0.8725 | 0.7149 | 0.8864 | |
| HCC1569 | HER2amp | Basal A | SB-3CT | MMP2/9 | MMP | 0.000256 | uM | 10872.144 | 1.0031 | 1.0040 | 1.5447 | |
| HCC1569 | HER2amp | Basal A | SB-3CT | MMP2/9 | MMP | 0.00128 | uM | 10872.144 | 1.0485 | 1.0622 | 1.5447 | |
| HCC1569 | HER2amp | Basal A | SB-3CT | MMP2/9 | MMP | 0.0064 | uM | 10872.144 | 1.0242 | 1.0312 | 1.5447 | |
| HCC1569 | HER2amp | Basal A | SB-3CT | MMP2/9 | MMP | 0.032 | uM | 10872.144 | 1.0276 | 1.0356 | 1.5447 | |
| HCC1569 | HER2amp | Basal A | SB-3CT | MMP2/9 | MMP | 0.16 | uM | 10872.144 | 1.0147 | 1.0190 | 1.5447 | |
| HCC1569 | HER2amp | Basal A | SB-3CT | MMP2/9 | MMP | 0.8 | uM | 10872.144 | 1.0069 | 1.0089 | 1.5447 | |
| HCC1569 | HER2amp | Basal A | SB-3CT | MMP2/9 | MMP | 4 | uM | 10872.144 | 1.0701 | 1.0897 | 1.5447 | |
| HCC1569 | HER2amp | Basal A | SB-3CT | MMP2/9 | MMP | 20 | uM | 10872.144 | 0.9626 | 0.9513 | 1.5447 | |
| HCC1569 | HER2amp | Basal A | SB-3CT | MMP2/9 | MMP | 100 | uM | 10872.144 | 0.8509 | 0.8015 | 1.5447 | |
| HCC1569 | HER2amp | Basal A | SB-3CT | MMP2/9 | MMP | 0.000427 | uM | 12523.168 | 0.9880 | 0.9734 | 0.9035 | |
| HCC1569 | HER2amp | Basal A | SB-3CT | MMP2/9 | MMP | 0.00213 | uM | 12523.168 | 1.0021 | 1.0046 | 0.9035 | |
| HCC1569 | HER2amp | Basal A | SB-3CT | MMP2/9 | MMP | 0.0107 | uM | 12523.168 | 1.0240 | 1.0533 | 0.9035 |