Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1395 | TNBC | Basal B | SB-3CT | MMP2/9 | MMP | 33.3 | uM | 12000.168 | 0.9491 | 0.8715 | 0.7873 | |
| HCC1395 | TNBC | Basal B | SB-3CT | MMP2/9 | MMP | 167 | uM | 12000.168 | 0.8924 | 0.7308 | 0.7873 | |
| HCC1395 | TNBC | Basal B | SB-3CT | MMP2/9 | MMP | 0.000256 | uM | 12084.144 | 0.9683 | 0.9566 | 1.4700 | |
| HCC1395 | TNBC | Basal B | SB-3CT | MMP2/9 | MMP | 0.00128 | uM | 12084.144 | 0.9048 | 0.8684 | 1.4700 | |
| HCC1395 | TNBC | Basal B | SB-3CT | MMP2/9 | MMP | 0.0064 | uM | 12084.144 | 0.9053 | 0.8691 | 1.4700 | |
| HCC1395 | TNBC | Basal B | SB-3CT | MMP2/9 | MMP | 0.032 | uM | 12084.144 | 0.9155 | 0.8834 | 1.4700 | |
| HCC1395 | TNBC | Basal B | SB-3CT | MMP2/9 | MMP | 0.16 | uM | 12084.144 | 0.9421 | 0.9205 | 1.4700 | |
| HCC1395 | TNBC | Basal B | SB-3CT | MMP2/9 | MMP | 0.8 | uM | 12084.144 | 1.0328 | 1.0444 | 1.4700 | |
| HCC1395 | TNBC | Basal B | SB-3CT | MMP2/9 | MMP | 4 | uM | 12084.144 | 0.8771 | 0.8293 | 1.4700 | |
| HCC1395 | TNBC | Basal B | SB-3CT | MMP2/9 | MMP | 20 | uM | 12084.144 | 0.8131 | 0.7374 | 1.4700 | |
| HCC1395 | TNBC | Basal B | SB-3CT | MMP2/9 | MMP | 100 | uM | 12084.144 | 0.6073 | 0.4245 | 1.4700 | |
| HCC1419 | HER2amp | Luminal | SB-3CT | MMP2/9 | MMP | 0.000427 | uM | 12001.168 | 0.9762 | 0.9045 | 0.4934 | |
| HCC1419 | HER2amp | Luminal | SB-3CT | MMP2/9 | MMP | 0.00213 | uM | 12001.168 | 0.9798 | 0.9188 | 0.4934 | |
| HCC1419 | HER2amp | Luminal | SB-3CT | MMP2/9 | MMP | 0.0107 | uM | 12001.168 | 1.0039 | 1.0156 | 0.4934 | |
| HCC1419 | HER2amp | Luminal | SB-3CT | MMP2/9 | MMP | 0.0533 | uM | 12001.168 | 0.9723 | 0.8893 | 0.4934 | |
| HCC1419 | HER2amp | Luminal | SB-3CT | MMP2/9 | MMP | 0.267 | uM | 12001.168 | 0.9827 | 0.9303 | 0.4934 | |
| HCC1419 | HER2amp | Luminal | SB-3CT | MMP2/9 | MMP | 1.33 | uM | 12001.168 | 1.0239 | 1.0979 | 0.4934 | |
| HCC1419 | HER2amp | Luminal | SB-3CT | MMP2/9 | MMP | 6.67 | uM | 12001.168 | 1.0132 | 1.0539 | 0.4934 | |
| HCC1419 | HER2amp | Luminal | SB-3CT | MMP2/9 | MMP | 33.3 | uM | 12001.168 | 0.9689 | 0.8759 | 0.4934 | |
| HCC1419 | HER2amp | Luminal | SB-3CT | MMP2/9 | MMP | 167 | uM | 12001.168 | 0.9411 | 0.7686 | 0.4934 | |
| HCC1428 | HR+ | Luminal | SB-3CT | MMP2/9 | MMP | 0.000256 | uM | 10693.144 | 1.0013 | 1.0031 | 0.8585 | |
| HCC1428 | HR+ | Luminal | SB-3CT | MMP2/9 | MMP | 0.00128 | uM | 10693.144 | 0.9434 | 0.8687 | 0.8585 | |
| HCC1428 | HR+ | Luminal | SB-3CT | MMP2/9 | MMP | 0.0064 | uM | 10693.144 | 1.0314 | 1.0734 | 0.8585 | |
| HCC1428 | HR+ | Luminal | SB-3CT | MMP2/9 | MMP | 0.032 | uM | 10693.144 | 1.0261 | 1.0610 | 0.8585 | |
| HCC1428 | HR+ | Luminal | SB-3CT | MMP2/9 | MMP | 0.16 | uM | 10693.144 | 1.0125 | 1.0292 | 0.8585 |