Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1143 | TNBC | Basal A | SB-3CT | MMP2/9 | MMP | 0.000256 | uM | 12112.144 | 0.9097 | 0.9036 | 1.9163 | |
| HCC1143 | TNBC | Basal A | SB-3CT | MMP2/9 | MMP | 0.00128 | uM | 12112.144 | 0.9470 | 0.9439 | 1.9163 | |
| HCC1143 | TNBC | Basal A | SB-3CT | MMP2/9 | MMP | 0.0064 | uM | 12112.144 | 0.9481 | 0.9451 | 1.9163 | |
| HCC1143 | TNBC | Basal A | SB-3CT | MMP2/9 | MMP | 0.032 | uM | 12112.144 | 0.9734 | 0.9721 | 1.9163 | |
| HCC1143 | TNBC | Basal A | SB-3CT | MMP2/9 | MMP | 0.16 | uM | 12112.144 | 0.8826 | 0.8738 | 1.9163 | |
| HCC1143 | TNBC | Basal A | SB-3CT | MMP2/9 | MMP | 0.8 | uM | 12112.144 | 0.9365 | 0.9327 | 1.9163 | |
| HCC1143 | TNBC | Basal A | SB-3CT | MMP2/9 | MMP | 4 | uM | 12112.144 | 0.9919 | 0.9915 | 1.9163 | |
| HCC1143 | TNBC | Basal A | SB-3CT | MMP2/9 | MMP | 20 | uM | 12112.144 | 0.8121 | 0.7942 | 1.9163 | |
| HCC1143 | TNBC | Basal A | SB-3CT | MMP2/9 | MMP | 100 | uM | 12112.144 | 0.6868 | 0.6439 | 1.9163 | |
| HCC1187 | TNBC | Basal A | SB-3CT | MMP2/9 | MMP | 0.000256 | uM | 10753.144 | 1.0452 | 1.0691 | 1.3008 | |
| HCC1187 | TNBC | Basal A | SB-3CT | MMP2/9 | MMP | 0.00128 | uM | 10753.144 | 0.9659 | 0.9474 | 1.3008 | |
| HCC1187 | TNBC | Basal A | SB-3CT | MMP2/9 | MMP | 0.0064 | uM | 10753.144 | 1.0198 | 1.0304 | 1.3008 | |
| HCC1187 | TNBC | Basal A | SB-3CT | MMP2/9 | MMP | 0.032 | uM | 10753.144 | 0.9642 | 0.9447 | 1.3008 | |
| HCC1187 | TNBC | Basal A | SB-3CT | MMP2/9 | MMP | 0.16 | uM | 10753.144 | 0.9630 | 0.9428 | 1.3008 | |
| HCC1187 | TNBC | Basal A | SB-3CT | MMP2/9 | MMP | 0.8 | uM | 10753.144 | 0.9939 | 0.9906 | 1.3008 | |
| HCC1187 | TNBC | Basal A | SB-3CT | MMP2/9 | MMP | 4 | uM | 10753.144 | 0.9219 | 0.8788 | 1.3008 | |
| HCC1187 | TNBC | Basal A | SB-3CT | MMP2/9 | MMP | 20 | uM | 10753.144 | 0.6014 | 0.3530 | 1.3008 | |
| HCC1187 | TNBC | Basal A | SB-3CT | MMP2/9 | MMP | 100 | uM | 10753.144 | 0.0149 | -0.9211 | 1.3008 | |
| HCC1395 | TNBC | Basal B | SB-3CT | MMP2/9 | MMP | 0.000427 | uM | 12000.168 | 0.9610 | 0.9014 | 0.7873 | |
| HCC1395 | TNBC | Basal B | SB-3CT | MMP2/9 | MMP | 0.00213 | uM | 12000.168 | 0.9573 | 0.8921 | 0.7873 | |
| HCC1395 | TNBC | Basal B | SB-3CT | MMP2/9 | MMP | 0.0107 | uM | 12000.168 | 0.9532 | 0.8818 | 0.7873 | |
| HCC1395 | TNBC | Basal B | SB-3CT | MMP2/9 | MMP | 0.0533 | uM | 12000.168 | 0.9502 | 0.8743 | 0.7873 | |
| HCC1395 | TNBC | Basal B | SB-3CT | MMP2/9 | MMP | 0.267 | uM | 12000.168 | 0.9583 | 0.8947 | 0.7873 | |
| HCC1395 | TNBC | Basal B | SB-3CT | MMP2/9 | MMP | 1.33 | uM | 12000.168 | 0.9828 | 0.9565 | 0.7873 | |
| HCC1395 | TNBC | Basal B | SB-3CT | MMP2/9 | MMP | 6.67 | uM | 12000.168 | 0.9435 | 0.8577 | 0.7873 |