Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1419 | HER2amp | Luminal | PS-1145 | IKK | NFKB | 379 | uM | 7437.065 | 1.0142 | 1.0552 | 0.5183 | |
| HCC1419 | HER2amp | Luminal | PS-1145 | IKK | NFKB | 1890 | uM | 7437.065 | 1.0032 | 1.0125 | 0.5183 | |
| HCC1419 | HER2amp | Luminal | PS-1145 | IKK | NFKB | 0.00485 | uM | 7440.065 | 0.9649 | 0.8807 | 0.5818 | |
| HCC1419 | HER2amp | Luminal | PS-1145 | IKK | NFKB | 0.0243 | uM | 7440.065 | 0.9516 | 0.8366 | 0.5818 | |
| HCC1419 | HER2amp | Luminal | PS-1145 | IKK | NFKB | 0.121 | uM | 7440.065 | 0.9549 | 0.8474 | 0.5818 | |
| HCC1419 | HER2amp | Luminal | PS-1145 | IKK | NFKB | 0.606 | uM | 7440.065 | 0.9816 | 0.9373 | 0.5818 | |
| HCC1419 | HER2amp | Luminal | PS-1145 | IKK | NFKB | 3.03 | uM | 7440.065 | 0.9457 | 0.8169 | 0.5818 | |
| HCC1419 | HER2amp | Luminal | PS-1145 | IKK | NFKB | 15.2 | uM | 7440.065 | 0.9786 | 0.9271 | 0.5818 | |
| HCC1419 | HER2amp | Luminal | PS-1145 | IKK | NFKB | 75.8 | uM | 7440.065 | 0.9470 | 0.8214 | 0.5818 | |
| HCC1419 | HER2amp | Luminal | PS-1145 | IKK | NFKB | 379 | uM | 7440.065 | 1.0015 | 1.0052 | 0.5818 | |
| HCC1419 | HER2amp | Luminal | PS-1145 | IKK | NFKB | 1890 | uM | 7440.065 | 0.9808 | 0.9343 | 0.5818 | |
| HCC1428 | HR+ | Luminal | PS-1145 | IKK | NFKB | 0.00485 | uM | 7442.065 | 1.0100 | 1.0256 | 0.7805 | |
| HCC1428 | HR+ | Luminal | PS-1145 | IKK | NFKB | 0.0243 | uM | 7442.065 | 1.0316 | 1.0813 | 0.7805 | |
| HCC1428 | HR+ | Luminal | PS-1145 | IKK | NFKB | 0.121 | uM | 7442.065 | 1.0134 | 1.0345 | 0.7805 | |
| HCC1428 | HR+ | Luminal | PS-1145 | IKK | NFKB | 0.606 | uM | 7442.065 | 1.0279 | 1.0717 | 0.7805 | |
| HCC1428 | HR+ | Luminal | PS-1145 | IKK | NFKB | 3.03 | uM | 7442.065 | 1.0013 | 1.0032 | 0.7805 | |
| HCC1428 | HR+ | Luminal | PS-1145 | IKK | NFKB | 15.2 | uM | 7442.065 | 1.0381 | 1.0982 | 0.7805 | |
| HCC1428 | HR+ | Luminal | PS-1145 | IKK | NFKB | 75.8 | uM | 7442.065 | 1.0858 | 1.2224 | 0.7805 | |
| HCC1428 | HR+ | Luminal | PS-1145 | IKK | NFKB | 379 | uM | 7442.065 | 1.0838 | 1.2171 | 0.7805 | |
| HCC1428 | HR+ | Luminal | PS-1145 | IKK | NFKB | 1890 | uM | 7442.065 | 1.0393 | 1.1012 | 0.7805 | |
| HCC1428 | HR+ | Luminal | PS-1145 | IKK | NFKB | 0.00485 | uM | 7443.065 | 1.0081 | 1.0183 | 0.8818 | |
| HCC1428 | HR+ | Luminal | PS-1145 | IKK | NFKB | 0.0243 | uM | 7443.065 | 1.0200 | 1.0453 | 0.8818 | |
| HCC1428 | HR+ | Luminal | PS-1145 | IKK | NFKB | 0.121 | uM | 7443.065 | 1.0293 | 1.0666 | 0.8818 | |
| HCC1428 | HR+ | Luminal | PS-1145 | IKK | NFKB | 0.606 | uM | 7443.065 | 1.0547 | 1.1245 | 0.8818 | |
| HCC1428 | HR+ | Luminal | PS-1145 | IKK | NFKB | 3.03 | uM | 7443.065 | 1.0593 | 1.1351 | 0.8818 |