Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
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HCC1569 | HER2amp | Basal A | Pertuzumab | 0.0000032 | mg/ml | 7447.102 | 0.9457 | 0.9333 | 1.6467 | |||
HCC1569 | HER2amp | Basal A | Pertuzumab | 0.000016 | mg/ml | 7447.102 | 0.9905 | 0.9885 | 1.6467 | |||
HCC1569 | HER2amp | Basal A | Pertuzumab | 0.00008 | mg/ml | 7447.102 | 0.9647 | 0.9568 | 1.6467 | |||
HCC1569 | HER2amp | Basal A | Pertuzumab | 0.0004 | mg/ml | 7447.102 | 0.9750 | 0.9695 | 1.6467 | |||
HCC1569 | HER2amp | Basal A | Pertuzumab | 0.002 | mg/ml | 7447.102 | 0.9593 | 0.9502 | 1.6467 | |||
HCC1569 | HER2amp | Basal A | Pertuzumab | 0.01 | mg/ml | 7447.102 | 0.9470 | 0.9350 | 1.6467 | |||
HCC1569 | HER2amp | Basal A | Pertuzumab | 0.05 | mg/ml | 7447.102 | 0.9457 | 0.9333 | 1.6467 | |||
HCC1569 | HER2amp | Basal A | Pertuzumab | 0.25 | mg/ml | 7447.102 | 0.9079 | 0.8861 | 1.6467 | |||
HCC1569 | HER2amp | Basal A | Pertuzumab | 1.25 | mg/ml | 7447.102 | 0.9179 | 0.8986 | 1.6467 | |||
MCF 10F | NM | - | Pertuzumab | 0.0000032 | mg/ml | 7487.102 | 0.9689 | 0.9590 | 1.5273 | |||
MCF 10F | NM | - | Pertuzumab | 0.000016 | mg/ml | 7487.102 | 0.9146 | 0.8864 | 1.5273 | |||
MCF 10F | NM | - | Pertuzumab | 0.00008 | mg/ml | 7487.102 | 0.9889 | 0.9854 | 1.5273 | |||
MCF 10F | NM | - | Pertuzumab | 0.0004 | mg/ml | 7487.102 | 0.9717 | 0.9628 | 1.5273 | |||
MCF 10F | NM | - | Pertuzumab | 0.002 | mg/ml | 7487.102 | 0.8741 | 0.8313 | 1.5273 | |||
MCF 10F | NM | - | Pertuzumab | 0.01 | mg/ml | 7487.102 | 0.9008 | 0.8678 | 1.5273 | |||
MCF 10F | NM | - | Pertuzumab | 0.05 | mg/ml | 7487.102 | 0.9180 | 0.8911 | 1.5273 | |||
MCF 10F | NM | - | Pertuzumab | 0.25 | mg/ml | 7487.102 | 0.8097 | 0.7418 | 1.5273 | |||
MCF 10F | NM | - | Pertuzumab | 1.25 | mg/ml | 7487.102 | 0.7477 | 0.6533 | 1.5273 | |||
MCF12A | NM | Basal B | Pertuzumab | 0.0000032 | mg/ml | 7489.102 | 0.9764 | 0.9804 | 2.4234 | |||
MCF12A | NM | Basal B | Pertuzumab | 0.000016 | mg/ml | 7489.102 | 0.9742 | 0.9785 | 2.4234 | |||
MCF12A | NM | Basal B | Pertuzumab | 0.00008 | mg/ml | 7489.102 | 0.9575 | 0.9645 | 2.4234 | |||
MCF12A | NM | Basal B | Pertuzumab | 0.0004 | mg/ml | 7489.102 | 0.9913 | 0.9928 | 2.4234 | |||
MCF12A | NM | Basal B | Pertuzumab | 0.002 | mg/ml | 7489.102 | 0.9273 | 0.9387 | 2.4234 | |||
MCF12A | NM | Basal B | Pertuzumab | 0.01 | mg/ml | 7489.102 | 0.9711 | 0.9760 | 2.4234 | |||
MCF12A | NM | Basal B | Pertuzumab | 0.05 | mg/ml | 7489.102 | 0.9618 | 0.9681 | 2.4234 |