Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)

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Cell Clinical Subtype Transcriptional Subtype Small Molecule Antibody Perturbagen Target Perturbagen Class Perturbagen Concentration Perturbagen Conc Unit Biological Replicate ID Relative Cell Count Normalized Growth Rate Inhibition Value Nominal Division Rate
HCC1569
HER2amp
Basal A
Pertuzumab
0.0000032
mg/ml
7447.102
0.9457 0.9333 1.6467
HCC1569
HER2amp
Basal A
Pertuzumab
0.000016
mg/ml
7447.102
0.9905 0.9885 1.6467
HCC1569
HER2amp
Basal A
Pertuzumab
0.00008
mg/ml
7447.102
0.9647 0.9568 1.6467
HCC1569
HER2amp
Basal A
Pertuzumab
0.0004
mg/ml
7447.102
0.9750 0.9695 1.6467
HCC1569
HER2amp
Basal A
Pertuzumab
0.002
mg/ml
7447.102
0.9593 0.9502 1.6467
HCC1569
HER2amp
Basal A
Pertuzumab
0.01
mg/ml
7447.102
0.9470 0.9350 1.6467
HCC1569
HER2amp
Basal A
Pertuzumab
0.05
mg/ml
7447.102
0.9457 0.9333 1.6467
HCC1569
HER2amp
Basal A
Pertuzumab
0.25
mg/ml
7447.102
0.9079 0.8861 1.6467
HCC1569
HER2amp
Basal A
Pertuzumab
1.25
mg/ml
7447.102
0.9179 0.8986 1.6467
MCF 10F
NM
-
Pertuzumab
0.0000032
mg/ml
7487.102
0.9689 0.9590 1.5273
MCF 10F
NM
-
Pertuzumab
0.000016
mg/ml
7487.102
0.9146 0.8864 1.5273
MCF 10F
NM
-
Pertuzumab
0.00008
mg/ml
7487.102
0.9889 0.9854 1.5273
MCF 10F
NM
-
Pertuzumab
0.0004
mg/ml
7487.102
0.9717 0.9628 1.5273
MCF 10F
NM
-
Pertuzumab
0.002
mg/ml
7487.102
0.8741 0.8313 1.5273
MCF 10F
NM
-
Pertuzumab
0.01
mg/ml
7487.102
0.9008 0.8678 1.5273
MCF 10F
NM
-
Pertuzumab
0.05
mg/ml
7487.102
0.9180 0.8911 1.5273
MCF 10F
NM
-
Pertuzumab
0.25
mg/ml
7487.102
0.8097 0.7418 1.5273
MCF 10F
NM
-
Pertuzumab
1.25
mg/ml
7487.102
0.7477 0.6533 1.5273
MCF12A
NM
Basal B
Pertuzumab
0.0000032
mg/ml
7489.102
0.9764 0.9804 2.4234
MCF12A
NM
Basal B
Pertuzumab
0.000016
mg/ml
7489.102
0.9742 0.9785 2.4234
MCF12A
NM
Basal B
Pertuzumab
0.00008
mg/ml
7489.102
0.9575 0.9645 2.4234
MCF12A
NM
Basal B
Pertuzumab
0.0004
mg/ml
7489.102
0.9913 0.9928 2.4234
MCF12A
NM
Basal B
Pertuzumab
0.002
mg/ml
7489.102
0.9273 0.9387 2.4234
MCF12A
NM
Basal B
Pertuzumab
0.01
mg/ml
7489.102
0.9711 0.9760 2.4234
MCF12A
NM
Basal B
Pertuzumab
0.05
mg/ml
7489.102
0.9618 0.9681 2.4234