Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
---|---|---|---|---|---|---|---|---|---|---|---|---|
MCF12A | NM | Basal B | Pertuzumab | 0.25 | mg/ml | 7489.102 | 0.8804 | 0.8976 | 2.4234 | |||
MCF12A | NM | Basal B | Pertuzumab | 1.25 | mg/ml | 7489.102 | 0.8528 | 0.8728 | 2.4234 | |||
184A1 | NM | Basal | PS-1145 | IKK | NFKB | 0.00485 | uM | 5894.065 | 1.0451 | 1.0557 | 1.6064 | |
184A1 | NM | Basal | PS-1145 | IKK | NFKB | 0.0243 | uM | 5894.065 | 1.0293 | 1.0363 | 1.6064 | |
184A1 | NM | Basal | PS-1145 | IKK | NFKB | 0.121 | uM | 5894.065 | 1.0092 | 1.0115 | 1.6064 | |
184A1 | NM | Basal | PS-1145 | IKK | NFKB | 0.606 | uM | 5894.065 | 1.0442 | 1.0545 | 1.6064 | |
184A1 | NM | Basal | PS-1145 | IKK | NFKB | 3.03 | uM | 5894.065 | 1.0480 | 1.0593 | 1.6064 | |
184A1 | NM | Basal | PS-1145 | IKK | NFKB | 15.2 | uM | 5894.065 | 1.0062 | 1.0077 | 1.6064 | |
184A1 | NM | Basal | PS-1145 | IKK | NFKB | 75.8 | uM | 5894.065 | 1.0259 | 1.0321 | 1.6064 | |
184A1 | NM | Basal | PS-1145 | IKK | NFKB | 379 | uM | 5894.065 | 0.9506 | 0.9379 | 1.6064 | |
184A1 | NM | Basal | PS-1145 | IKK | NFKB | 1890 | uM | 5894.065 | 0.8734 | 0.8384 | 1.6064 | |
184A1 | NM | Basal | PS-1145 | IKK | NFKB | 0.00485 | uM | 5895.065 | 1.0767 | 1.1105 | 1.3748 | |
184A1 | NM | Basal | PS-1145 | IKK | NFKB | 0.0243 | uM | 5895.065 | 1.1328 | 1.1899 | 1.3748 | |
184A1 | NM | Basal | PS-1145 | IKK | NFKB | 0.121 | uM | 5895.065 | 1.0964 | 1.1385 | 1.3748 | |
184A1 | NM | Basal | PS-1145 | IKK | NFKB | 0.606 | uM | 5895.065 | 1.0610 | 1.0880 | 1.3748 | |
184A1 | NM | Basal | PS-1145 | IKK | NFKB | 3.03 | uM | 5895.065 | 1.0597 | 1.0861 | 1.3748 | |
184A1 | NM | Basal | PS-1145 | IKK | NFKB | 15.2 | uM | 5895.065 | 1.1299 | 1.1858 | 1.3748 | |
184A1 | NM | Basal | PS-1145 | IKK | NFKB | 75.8 | uM | 5895.065 | 1.0184 | 1.0267 | 1.3748 | |
184A1 | NM | Basal | PS-1145 | IKK | NFKB | 379 | uM | 5895.065 | 1.0021 | 1.0031 | 1.3748 | |
184A1 | NM | Basal | PS-1145 | IKK | NFKB | 1890 | uM | 5895.065 | 1.0092 | 1.0133 | 1.3748 | |
184B5 | NM | Basal | PS-1145 | IKK | NFKB | 0.00485 | uM | 5896.065 | 0.9942 | 0.9922 | 1.4978 | |
184B5 | NM | Basal | PS-1145 | IKK | NFKB | 0.0243 | uM | 5896.065 | 0.9839 | 0.9785 | 1.4978 | |
184B5 | NM | Basal | PS-1145 | IKK | NFKB | 0.121 | uM | 5896.065 | 0.9785 | 0.9711 | 1.4978 | |
184B5 | NM | Basal | PS-1145 | IKK | NFKB | 0.606 | uM | 5896.065 | 0.9685 | 0.9577 | 1.4978 | |
184B5 | NM | Basal | PS-1145 | IKK | NFKB | 3.03 | uM | 5896.065 | 0.9904 | 0.9872 | 1.4978 |