Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1395 | TNBC | Basal B | PS-1145 | IKK | NFKB | 0.00485 | uM | 7435.065 | 1.0015 | 1.0035 | 0.8513 | |
| HCC1395 | TNBC | Basal B | PS-1145 | IKK | NFKB | 0.0243 | uM | 7435.065 | 0.9428 | 0.8662 | 0.8513 | |
| HCC1395 | TNBC | Basal B | PS-1145 | IKK | NFKB | 0.121 | uM | 7435.065 | 0.9656 | 0.9195 | 0.8513 | |
| HCC1395 | TNBC | Basal B | PS-1145 | IKK | NFKB | 0.606 | uM | 7435.065 | 0.9666 | 0.9218 | 0.8513 | |
| HCC1395 | TNBC | Basal B | PS-1145 | IKK | NFKB | 3.03 | uM | 7435.065 | 0.9811 | 0.9558 | 0.8513 | |
| HCC1395 | TNBC | Basal B | PS-1145 | IKK | NFKB | 15.2 | uM | 7435.065 | 0.8566 | 0.6676 | 0.8513 | |
| HCC1395 | TNBC | Basal B | PS-1145 | IKK | NFKB | 75.8 | uM | 7435.065 | 0.9663 | 0.9210 | 0.8513 | |
| HCC1395 | TNBC | Basal B | PS-1145 | IKK | NFKB | 379 | uM | 7435.065 | 0.9102 | 0.7907 | 0.8513 | |
| HCC1395 | TNBC | Basal B | PS-1145 | IKK | NFKB | 1890 | uM | 7435.065 | 0.8840 | 0.7303 | 0.8513 | |
| HCC1395 | TNBC | Basal B | PS-1145 | IKK | NFKB | 0.00485 | uM | 7436.065 | 1.0135 | 1.0222 | 1.2177 | |
| HCC1395 | TNBC | Basal B | PS-1145 | IKK | NFKB | 0.0243 | uM | 7436.065 | 0.9978 | 0.9964 | 1.2177 | |
| HCC1395 | TNBC | Basal B | PS-1145 | IKK | NFKB | 0.121 | uM | 7436.065 | 0.9933 | 0.9889 | 1.2177 | |
| HCC1395 | TNBC | Basal B | PS-1145 | IKK | NFKB | 0.606 | uM | 7436.065 | 1.0369 | 1.0605 | 1.2177 | |
| HCC1395 | TNBC | Basal B | PS-1145 | IKK | NFKB | 3.03 | uM | 7436.065 | 1.0336 | 1.0550 | 1.2177 | |
| HCC1395 | TNBC | Basal B | PS-1145 | IKK | NFKB | 15.2 | uM | 7436.065 | 0.9937 | 0.9897 | 1.2177 | |
| HCC1395 | TNBC | Basal B | PS-1145 | IKK | NFKB | 75.8 | uM | 7436.065 | 1.0161 | 1.0264 | 1.2177 | |
| HCC1395 | TNBC | Basal B | PS-1145 | IKK | NFKB | 379 | uM | 7436.065 | 0.9189 | 0.8657 | 1.2177 | |
| HCC1395 | TNBC | Basal B | PS-1145 | IKK | NFKB | 1890 | uM | 7436.065 | 0.8757 | 0.7935 | 1.2177 | |
| HCC1419 | HER2amp | Luminal | PS-1145 | IKK | NFKB | 0.00485 | uM | 7437.065 | 1.0303 | 1.1186 | 0.5183 | |
| HCC1419 | HER2amp | Luminal | PS-1145 | IKK | NFKB | 0.0243 | uM | 7437.065 | 0.9818 | 0.9305 | 0.5183 | |
| HCC1419 | HER2amp | Luminal | PS-1145 | IKK | NFKB | 0.121 | uM | 7437.065 | 1.0039 | 1.0150 | 0.5183 | |
| HCC1419 | HER2amp | Luminal | PS-1145 | IKK | NFKB | 0.606 | uM | 7437.065 | 0.9892 | 0.9584 | 0.5183 | |
| HCC1419 | HER2amp | Luminal | PS-1145 | IKK | NFKB | 3.03 | uM | 7437.065 | 0.9721 | 0.8937 | 0.5183 | |
| HCC1419 | HER2amp | Luminal | PS-1145 | IKK | NFKB | 15.2 | uM | 7437.065 | 0.9785 | 0.9179 | 0.5183 | |
| HCC1419 | HER2amp | Luminal | PS-1145 | IKK | NFKB | 75.8 | uM | 7437.065 | 0.9477 | 0.8030 | 0.5183 |