Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SUM52PE | HR+ | Luminal | PD184352 | MEK | MAPK | 0.000853 | uM | 10695.146 | 0.9999 | 0.9999 | 1.4179 | |
| SUM52PE | HR+ | Luminal | PD184352 | MEK | MAPK | 0.000853 | uM | 10695.146 | 0.9999 | 0.9999 | 1.4179 | |
| SUM52PE | HR+ | Luminal | PD184352 | MEK | MAPK | 0.00427 | uM | 10695.146 | 0.9606 | 0.9442 | 1.4179 | |
| SUM52PE | HR+ | Luminal | PD184352 | MEK | MAPK | 0.00427 | uM | 10695.146 | 0.9606 | 0.9442 | 1.4179 | |
| SUM52PE | HR+ | Luminal | PD184352 | MEK | MAPK | 0.0213 | uM | 10695.146 | 1.0243 | 1.0342 | 1.4179 | |
| SUM52PE | HR+ | Luminal | PD184352 | MEK | MAPK | 0.0213 | uM | 10695.146 | 1.0243 | 1.0342 | 1.4179 | |
| SUM52PE | HR+ | Luminal | PD184352 | MEK | MAPK | 0.107 | uM | 10695.146 | 1.0872 | 1.1215 | 1.4179 | |
| SUM52PE | HR+ | Luminal | PD184352 | MEK | MAPK | 0.107 | uM | 10695.146 | 1.0872 | 1.1215 | 1.4179 | |
| SUM52PE | HR+ | Luminal | PD184352 | MEK | MAPK | 0.533 | uM | 10695.146 | 1.0002 | 1.0003 | 1.4179 | |
| SUM52PE | HR+ | Luminal | PD184352 | MEK | MAPK | 0.533 | uM | 10695.146 | 1.0002 | 1.0003 | 1.4179 | |
| SUM52PE | HR+ | Luminal | PD184352 | MEK | MAPK | 2.67 | uM | 10695.146 | 0.9664 | 0.9524 | 1.4179 | |
| SUM52PE | HR+ | Luminal | PD184352 | MEK | MAPK | 2.67 | uM | 10695.146 | 0.9664 | 0.9524 | 1.4179 | |
| SUM52PE | HR+ | Luminal | PD184352 | MEK | MAPK | 13.3 | uM | 10695.146 | 0.9605 | 0.9439 | 1.4179 | |
| SUM52PE | HR+ | Luminal | PD184352 | MEK | MAPK | 13.3 | uM | 10695.146 | 0.9605 | 0.9439 | 1.4179 | |
| SUM52PE | HR+ | Luminal | PD184352 | MEK | MAPK | 66.7 | uM | 10695.146 | 0.7367 | 0.6123 | 1.4179 | |
| SUM52PE | HR+ | Luminal | PD184352 | MEK | MAPK | 66.7 | uM | 10695.146 | 0.7367 | 0.6123 | 1.4179 | |
| SUM52PE | HR+ | Luminal | PD184352 | MEK | MAPK | 0.0000853 | uM | 11852.155 | 0.9883 | 0.9846 | 1.5196 | |
| SUM52PE | HR+ | Luminal | PD184352 | MEK | MAPK | 0.0000853 | uM | 11852.155 | 0.9883 | 0.9846 | 1.5196 | |
| SUM52PE | HR+ | Luminal | PD184352 | MEK | MAPK | 0.000427 | uM | 11852.155 | 0.9540 | 0.9389 | 1.5196 | |
| SUM52PE | HR+ | Luminal | PD184352 | MEK | MAPK | 0.000427 | uM | 11852.155 | 0.9540 | 0.9389 | 1.5196 | |
| SUM52PE | HR+ | Luminal | PD184352 | MEK | MAPK | 0.00213 | uM | 11852.155 | 1.0003 | 1.0004 | 1.5196 | |
| SUM52PE | HR+ | Luminal | PD184352 | MEK | MAPK | 0.00213 | uM | 11852.155 | 1.0003 | 1.0004 | 1.5196 | |
| SUM52PE | HR+ | Luminal | PD184352 | MEK | MAPK | 0.0107 | uM | 11852.155 | 0.9720 | 0.9629 | 1.5196 | |
| SUM52PE | HR+ | Luminal | PD184352 | MEK | MAPK | 0.0107 | uM | 11852.155 | 0.9720 | 0.9629 | 1.5196 | |
| SUM52PE | HR+ | Luminal | PD184352 | MEK | MAPK | 0.0533 | uM | 11852.155 | 1.0005 | 1.0007 | 1.5196 |