Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SUM52PE | HR+ | Luminal | PD184352 | MEK | MAPK | 0.0533 | uM | 11852.155 | 1.0005 | 1.0007 | 1.5196 | |
| SUM52PE | HR+ | Luminal | PD184352 | MEK | MAPK | 0.267 | uM | 11852.155 | 0.9304 | 0.9072 | 1.5196 | |
| SUM52PE | HR+ | Luminal | PD184352 | MEK | MAPK | 0.267 | uM | 11852.155 | 0.9304 | 0.9072 | 1.5196 | |
| SUM52PE | HR+ | Luminal | PD184352 | MEK | MAPK | 1.33 | uM | 11852.155 | 0.9384 | 0.9181 | 1.5196 | |
| SUM52PE | HR+ | Luminal | PD184352 | MEK | MAPK | 1.33 | uM | 11852.155 | 0.9384 | 0.9181 | 1.5196 | |
| SUM52PE | HR+ | Luminal | PD184352 | MEK | MAPK | 6.67 | uM | 11852.155 | 0.9423 | 0.9233 | 1.5196 | |
| SUM52PE | HR+ | Luminal | PD184352 | MEK | MAPK | 6.67 | uM | 11852.155 | 0.9423 | 0.9233 | 1.5196 | |
| SUM52PE | HR+ | Luminal | PD184352 | MEK | MAPK | 33.3 | uM | 11852.155 | 0.9102 | 0.8800 | 1.5196 | |
| SUM52PE | HR+ | Luminal | PD184352 | MEK | MAPK | 33.3 | uM | 11852.155 | 0.9102 | 0.8800 | 1.5196 | |
| T47D | HR+ | Luminal | PD184352 | MEK | MAPK | 0.0000853 | uM | 10939.155 | 0.9217 | 0.8951 | 1.5150 | |
| T47D | HR+ | Luminal | PD184352 | MEK | MAPK | 0.0000853 | uM | 10939.155 | 0.9217 | 0.8951 | 1.5150 | |
| T47D | HR+ | Luminal | PD184352 | MEK | MAPK | 0.000427 | uM | 10939.155 | 0.9625 | 0.9502 | 1.5150 | |
| T47D | HR+ | Luminal | PD184352 | MEK | MAPK | 0.000427 | uM | 10939.155 | 0.9625 | 0.9502 | 1.5150 | |
| T47D | HR+ | Luminal | PD184352 | MEK | MAPK | 0.00213 | uM | 10939.155 | 0.9709 | 0.9615 | 1.5150 | |
| T47D | HR+ | Luminal | PD184352 | MEK | MAPK | 0.00213 | uM | 10939.155 | 0.9709 | 0.9615 | 1.5150 | |
| T47D | HR+ | Luminal | PD184352 | MEK | MAPK | 0.0107 | uM | 10939.155 | 0.9540 | 0.9388 | 1.5150 | |
| T47D | HR+ | Luminal | PD184352 | MEK | MAPK | 0.0107 | uM | 10939.155 | 0.9540 | 0.9388 | 1.5150 | |
| T47D | HR+ | Luminal | PD184352 | MEK | MAPK | 0.0533 | uM | 10939.155 | 0.9406 | 0.9208 | 1.5150 | |
| T47D | HR+ | Luminal | PD184352 | MEK | MAPK | 0.0533 | uM | 10939.155 | 0.9406 | 0.9208 | 1.5150 | |
| T47D | HR+ | Luminal | PD184352 | MEK | MAPK | 0.267 | uM | 10939.155 | 0.9786 | 0.9717 | 1.5150 | |
| T47D | HR+ | Luminal | PD184352 | MEK | MAPK | 0.267 | uM | 10939.155 | 0.9786 | 0.9717 | 1.5150 | |
| T47D | HR+ | Luminal | PD184352 | MEK | MAPK | 1.33 | uM | 10939.155 | 1.0097 | 1.0128 | 1.5150 | |
| T47D | HR+ | Luminal | PD184352 | MEK | MAPK | 1.33 | uM | 10939.155 | 1.0097 | 1.0128 | 1.5150 | |
| T47D | HR+ | Luminal | PD184352 | MEK | MAPK | 6.67 | uM | 10939.155 | 0.9633 | 0.9513 | 1.5150 | |
| T47D | HR+ | Luminal | PD184352 | MEK | MAPK | 6.67 | uM | 10939.155 | 0.9633 | 0.9513 | 1.5150 |