Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| T47D | HR+ | Luminal | PD184352 | MEK | MAPK | 33.3 | uM | 10939.155 | 1.0251 | 1.0331 | 1.5150 | |
| T47D | HR+ | Luminal | PD184352 | MEK | MAPK | 33.3 | uM | 10939.155 | 1.0251 | 1.0331 | 1.5150 | |
| T47DKBLUC | Unknown | Unknown | PD184352 | MEK | MAPK | 0.0000853 | uM | 12608.155 | 0.9913 | 0.9849 | 1.1556 | |
| T47DKBLUC | Unknown | Unknown | PD184352 | MEK | MAPK | 0.0000853 | uM | 12608.155 | 0.9913 | 0.9849 | 1.1556 | |
| T47DKBLUC | Unknown | Unknown | PD184352 | MEK | MAPK | 0.000427 | uM | 12608.155 | 0.9681 | 0.9447 | 1.1556 | |
| T47DKBLUC | Unknown | Unknown | PD184352 | MEK | MAPK | 0.000427 | uM | 12608.155 | 0.9681 | 0.9447 | 1.1556 | |
| T47DKBLUC | Unknown | Unknown | PD184352 | MEK | MAPK | 0.00213 | uM | 12608.155 | 0.9808 | 0.9667 | 1.1556 | |
| T47DKBLUC | Unknown | Unknown | PD184352 | MEK | MAPK | 0.00213 | uM | 12608.155 | 0.9808 | 0.9667 | 1.1556 | |
| T47DKBLUC | Unknown | Unknown | PD184352 | MEK | MAPK | 0.0107 | uM | 12608.155 | 0.9871 | 0.9776 | 1.1556 | |
| T47DKBLUC | Unknown | Unknown | PD184352 | MEK | MAPK | 0.0107 | uM | 12608.155 | 0.9871 | 0.9776 | 1.1556 | |
| T47DKBLUC | Unknown | Unknown | PD184352 | MEK | MAPK | 0.0533 | uM | 12608.155 | 0.9876 | 0.9785 | 1.1556 | |
| T47DKBLUC | Unknown | Unknown | PD184352 | MEK | MAPK | 0.0533 | uM | 12608.155 | 0.9876 | 0.9785 | 1.1556 | |
| T47DKBLUC | Unknown | Unknown | PD184352 | MEK | MAPK | 0.267 | uM | 12608.155 | 0.9700 | 0.9481 | 1.1556 | |
| T47DKBLUC | Unknown | Unknown | PD184352 | MEK | MAPK | 0.267 | uM | 12608.155 | 0.9700 | 0.9481 | 1.1556 | |
| T47DKBLUC | Unknown | Unknown | PD184352 | MEK | MAPK | 1.33 | uM | 12608.155 | 1.0143 | 1.0247 | 1.1556 | |
| T47DKBLUC | Unknown | Unknown | PD184352 | MEK | MAPK | 1.33 | uM | 12608.155 | 1.0143 | 1.0247 | 1.1556 | |
| T47DKBLUC | Unknown | Unknown | PD184352 | MEK | MAPK | 6.67 | uM | 12608.155 | 0.9690 | 0.9462 | 1.1556 | |
| T47DKBLUC | Unknown | Unknown | PD184352 | MEK | MAPK | 6.67 | uM | 12608.155 | 0.9690 | 0.9462 | 1.1556 | |
| T47DKBLUC | Unknown | Unknown | PD184352 | MEK | MAPK | 33.3 | uM | 12608.155 | 0.9591 | 0.9291 | 1.1556 | |
| T47DKBLUC | Unknown | Unknown | PD184352 | MEK | MAPK | 33.3 | uM | 12608.155 | 0.9591 | 0.9291 | 1.1556 | |
| UACC-812 | HER2amp | Luminal | PD184352 | MEK | MAPK | 0.000171 | uM | 10754.146 | 1.0206 | 1.0329 | 1.2483 | |
| UACC-812 | HER2amp | Luminal | PD184352 | MEK | MAPK | 0.000171 | uM | 10754.146 | 1.0206 | 1.0329 | 1.2483 | |
| UACC-812 | HER2amp | Luminal | PD184352 | MEK | MAPK | 0.000853 | uM | 10754.146 | 1.0123 | 1.0197 | 1.2483 | |
| UACC-812 | HER2amp | Luminal | PD184352 | MEK | MAPK | 0.000853 | uM | 10754.146 | 1.0123 | 1.0197 | 1.2483 | |
| UACC-812 | HER2amp | Luminal | PD184352 | MEK | MAPK | 0.00427 | uM | 10754.146 | 0.9333 | 0.8924 | 1.2483 |