Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| UACC-812 | HER2amp | Luminal | PD184352 | MEK | MAPK | 0.00427 | uM | 10754.146 | 0.9333 | 0.8924 | 1.2483 | |
| UACC-812 | HER2amp | Luminal | PD184352 | MEK | MAPK | 0.0213 | uM | 10754.146 | 1.0475 | 1.0758 | 1.2483 | |
| UACC-812 | HER2amp | Luminal | PD184352 | MEK | MAPK | 0.0213 | uM | 10754.146 | 1.0475 | 1.0758 | 1.2483 | |
| UACC-812 | HER2amp | Luminal | PD184352 | MEK | MAPK | 0.107 | uM | 10754.146 | 1.1042 | 1.1653 | 1.2483 | |
| UACC-812 | HER2amp | Luminal | PD184352 | MEK | MAPK | 0.107 | uM | 10754.146 | 1.1042 | 1.1653 | 1.2483 | |
| UACC-812 | HER2amp | Luminal | PD184352 | MEK | MAPK | 0.533 | uM | 10754.146 | 1.0763 | 1.1214 | 1.2483 | |
| UACC-812 | HER2amp | Luminal | PD184352 | MEK | MAPK | 0.533 | uM | 10754.146 | 1.0763 | 1.1214 | 1.2483 | |
| UACC-812 | HER2amp | Luminal | PD184352 | MEK | MAPK | 2.67 | uM | 10754.146 | 1.0448 | 1.0714 | 1.2483 | |
| UACC-812 | HER2amp | Luminal | PD184352 | MEK | MAPK | 2.67 | uM | 10754.146 | 1.0448 | 1.0714 | 1.2483 | |
| UACC-812 | HER2amp | Luminal | PD184352 | MEK | MAPK | 13.3 | uM | 10754.146 | 1.0297 | 1.0475 | 1.2483 | |
| UACC-812 | HER2amp | Luminal | PD184352 | MEK | MAPK | 13.3 | uM | 10754.146 | 1.0297 | 1.0475 | 1.2483 | |
| UACC-812 | HER2amp | Luminal | PD184352 | MEK | MAPK | 66.7 | uM | 10754.146 | 1.0256 | 1.0409 | 1.2483 | |
| UACC-812 | HER2amp | Luminal | PD184352 | MEK | MAPK | 66.7 | uM | 10754.146 | 1.0256 | 1.0409 | 1.2483 | |
| UACC-812 | HER2amp | Luminal | PD184352 | MEK | MAPK | 0.0000853 | uM | 11938.155 | 0.9076 | 0.7379 | 0.6903 | |
| UACC-812 | HER2amp | Luminal | PD184352 | MEK | MAPK | 0.0000853 | uM | 11938.155 | 0.9076 | 0.7379 | 0.6903 | |
| UACC-812 | HER2amp | Luminal | PD184352 | MEK | MAPK | 0.000427 | uM | 11938.155 | 0.8395 | 0.5522 | 0.6903 | |
| UACC-812 | HER2amp | Luminal | PD184352 | MEK | MAPK | 0.000427 | uM | 11938.155 | 0.8395 | 0.5522 | 0.6903 | |
| UACC-812 | HER2amp | Luminal | PD184352 | MEK | MAPK | 0.00213 | uM | 11938.155 | 0.9467 | 0.8475 | 0.6903 | |
| UACC-812 | HER2amp | Luminal | PD184352 | MEK | MAPK | 0.00213 | uM | 11938.155 | 0.9467 | 0.8475 | 0.6903 | |
| UACC-812 | HER2amp | Luminal | PD184352 | MEK | MAPK | 0.0107 | uM | 11938.155 | 0.8912 | 0.6927 | 0.6903 | |
| UACC-812 | HER2amp | Luminal | PD184352 | MEK | MAPK | 0.0107 | uM | 11938.155 | 0.8912 | 0.6927 | 0.6903 | |
| UACC-812 | HER2amp | Luminal | PD184352 | MEK | MAPK | 0.0533 | uM | 11938.155 | 0.9449 | 0.8424 | 0.6903 | |
| UACC-812 | HER2amp | Luminal | PD184352 | MEK | MAPK | 0.0533 | uM | 11938.155 | 0.9449 | 0.8424 | 0.6903 | |
| UACC-812 | HER2amp | Luminal | PD184352 | MEK | MAPK | 0.267 | uM | 11938.155 | 0.9507 | 0.8587 | 0.6903 | |
| UACC-812 | HER2amp | Luminal | PD184352 | MEK | MAPK | 0.267 | uM | 11938.155 | 0.9507 | 0.8587 | 0.6903 |