Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MX1 | Unknown | Unknown | PD184352 | MEK | MAPK | 0.0107 | uM | 12220.155 | 0.8969 | 0.5986 | 0.4858 | |
| MX1 | Unknown | Unknown | PD184352 | MEK | MAPK | 0.0533 | uM | 12220.155 | 0.8989 | 0.6058 | 0.4858 | |
| MX1 | Unknown | Unknown | PD184352 | MEK | MAPK | 0.0533 | uM | 12220.155 | 0.8989 | 0.6058 | 0.4858 | |
| MX1 | Unknown | Unknown | PD184352 | MEK | MAPK | 0.267 | uM | 12220.155 | 0.8717 | 0.5077 | 0.4858 | |
| MX1 | Unknown | Unknown | PD184352 | MEK | MAPK | 0.267 | uM | 12220.155 | 0.8717 | 0.5077 | 0.4858 | |
| MX1 | Unknown | Unknown | PD184352 | MEK | MAPK | 1.33 | uM | 12220.155 | 0.9498 | 0.7987 | 0.4858 | |
| MX1 | Unknown | Unknown | PD184352 | MEK | MAPK | 1.33 | uM | 12220.155 | 0.9498 | 0.7987 | 0.4858 | |
| MX1 | Unknown | Unknown | PD184352 | MEK | MAPK | 6.67 | uM | 12220.155 | 0.8910 | 0.5769 | 0.4858 | |
| MX1 | Unknown | Unknown | PD184352 | MEK | MAPK | 6.67 | uM | 12220.155 | 0.8910 | 0.5769 | 0.4858 | |
| MX1 | Unknown | Unknown | PD184352 | MEK | MAPK | 33.3 | uM | 12220.155 | 0.7529 | 0.1151 | 0.4858 | |
| MX1 | Unknown | Unknown | PD184352 | MEK | MAPK | 33.3 | uM | 12220.155 | 0.7529 | 0.1151 | 0.4858 | |
| SK-BR-3 | HER2amp | Luminal | PD184352 | MEK | MAPK | 0.0000853 | uM | 11851.155 | 0.8936 | 0.8607 | 1.5585 | |
| SK-BR-3 | HER2amp | Luminal | PD184352 | MEK | MAPK | 0.0000853 | uM | 11851.155 | 0.8936 | 0.8607 | 1.5585 | |
| SK-BR-3 | HER2amp | Luminal | PD184352 | MEK | MAPK | 0.000427 | uM | 11851.155 | 0.8940 | 0.8612 | 1.5585 | |
| SK-BR-3 | HER2amp | Luminal | PD184352 | MEK | MAPK | 0.000427 | uM | 11851.155 | 0.8940 | 0.8612 | 1.5585 | |
| SK-BR-3 | HER2amp | Luminal | PD184352 | MEK | MAPK | 0.00213 | uM | 11851.155 | 0.9285 | 0.9071 | 1.5585 | |
| SK-BR-3 | HER2amp | Luminal | PD184352 | MEK | MAPK | 0.00213 | uM | 11851.155 | 0.9285 | 0.9071 | 1.5585 | |
| SK-BR-3 | HER2amp | Luminal | PD184352 | MEK | MAPK | 0.0107 | uM | 11851.155 | 0.9188 | 0.8942 | 1.5585 | |
| SK-BR-3 | HER2amp | Luminal | PD184352 | MEK | MAPK | 0.0107 | uM | 11851.155 | 0.9188 | 0.8942 | 1.5585 | |
| SK-BR-3 | HER2amp | Luminal | PD184352 | MEK | MAPK | 0.0533 | uM | 11851.155 | 0.9228 | 0.8995 | 1.5585 | |
| SK-BR-3 | HER2amp | Luminal | PD184352 | MEK | MAPK | 0.0533 | uM | 11851.155 | 0.9228 | 0.8995 | 1.5585 | |
| SK-BR-3 | HER2amp | Luminal | PD184352 | MEK | MAPK | 0.267 | uM | 11851.155 | 0.9020 | 0.8719 | 1.5585 | |
| SK-BR-3 | HER2amp | Luminal | PD184352 | MEK | MAPK | 0.267 | uM | 11851.155 | 0.9020 | 0.8719 | 1.5585 | |
| SK-BR-3 | HER2amp | Luminal | PD184352 | MEK | MAPK | 1.33 | uM | 11851.155 | 0.9111 | 0.8840 | 1.5585 | |
| SK-BR-3 | HER2amp | Luminal | PD184352 | MEK | MAPK | 1.33 | uM | 11851.155 | 0.9111 | 0.8840 | 1.5585 |