Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC2185 | TNBC | Luminal | AG1478 | EGFR | ErbB | 0.267 | uM | 7848.016 | 1.0070 | 1.0292 | 0.4818 | |
| HCC2185 | TNBC | Luminal | AG1478 | EGFR | ErbB | 1.33 | uM | 7848.016 | 0.9641 | 0.8540 | 0.4818 | |
| HCC2185 | TNBC | Luminal | AG1478 | EGFR | ErbB | 6.67 | uM | 7848.016 | 0.9510 | 0.8018 | 0.4818 | |
| HCC2185 | TNBC | Luminal | AG1478 | EGFR | ErbB | 33.3 | uM | 7848.016 | 0.9365 | 0.7455 | 0.4818 | |
| HCC2185 | TNBC | Luminal | AG1478 | EGFR | ErbB | 167 | uM | 7848.016 | 0.9434 | 0.7723 | 0.4818 | |
| HCC2185 | TNBC | Luminal | AG1478 | EGFR | ErbB | 0.000427 | uM | 7849.016 | 1.0129 | 1.0765 | 0.3419 | |
| HCC2185 | TNBC | Luminal | AG1478 | EGFR | ErbB | 0.00213 | uM | 7849.016 | 0.9919 | 0.9529 | 0.3419 | |
| HCC2185 | TNBC | Luminal | AG1478 | EGFR | ErbB | 0.0107 | uM | 7849.016 | 1.0133 | 1.0786 | 0.3419 | |
| HCC2185 | TNBC | Luminal | AG1478 | EGFR | ErbB | 0.0533 | uM | 7849.016 | 0.9672 | 0.8139 | 0.3419 | |
| HCC2185 | TNBC | Luminal | AG1478 | EGFR | ErbB | 0.267 | uM | 7849.016 | 1.0000 | 1.0000 | 0.3419 | |
| HCC2185 | TNBC | Luminal | AG1478 | EGFR | ErbB | 1.33 | uM | 7849.016 | 0.9439 | 0.6894 | 0.3419 | |
| HCC2185 | TNBC | Luminal | AG1478 | EGFR | ErbB | 6.67 | uM | 7849.016 | 0.9549 | 0.7472 | 0.3419 | |
| HCC2185 | TNBC | Luminal | AG1478 | EGFR | ErbB | 33.3 | uM | 7849.016 | 0.9371 | 0.6540 | 0.3419 | |
| HCC2185 | TNBC | Luminal | AG1478 | EGFR | ErbB | 167 | uM | 7849.016 | 0.8617 | 0.2939 | 0.3419 | |
| HCC3153 | TNBC | Basal A | AG1478 | EGFR | ErbB | 0.000427 | uM | 7853.016 | 0.9867 | 0.9835 | 1.6178 | |
| HCC3153 | TNBC | Basal A | AG1478 | EGFR | ErbB | 0.00213 | uM | 7853.016 | 0.9735 | 0.9670 | 1.6178 | |
| HCC3153 | TNBC | Basal A | AG1478 | EGFR | ErbB | 0.0107 | uM | 7853.016 | 0.9975 | 0.9969 | 1.6178 | |
| HCC3153 | TNBC | Basal A | AG1478 | EGFR | ErbB | 0.0533 | uM | 7853.016 | 1.0375 | 1.0460 | 1.6178 | |
| HCC3153 | TNBC | Basal A | AG1478 | EGFR | ErbB | 0.267 | uM | 7853.016 | 0.9560 | 0.9452 | 1.6178 | |
| HCC3153 | TNBC | Basal A | AG1478 | EGFR | ErbB | 1.33 | uM | 7853.016 | 0.9906 | 0.9884 | 1.6178 | |
| HCC3153 | TNBC | Basal A | AG1478 | EGFR | ErbB | 6.67 | uM | 7853.016 | 0.8386 | 0.7938 | 1.6178 | |
| HCC3153 | TNBC | Basal A | AG1478 | EGFR | ErbB | 33.3 | uM | 7853.016 | 0.9283 | 0.9101 | 1.6178 | |
| HCC3153 | TNBC | Basal A | AG1478 | EGFR | ErbB | 167 | uM | 7853.016 | 0.9623 | 0.9530 | 1.6178 | |
| HCC38 | TNBC | Basal B | AG1478 | EGFR | ErbB | 0.000427 | uM | 7854.016 | 1.1467 | 1.3257 | 0.9074 | |
| HCC38 | TNBC | Basal B | AG1478 | EGFR | ErbB | 0.00213 | uM | 7854.016 | 0.9563 | 0.9039 | 0.9074 |