Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC38 | TNBC | Basal B | AG1478 | EGFR | ErbB | 0.0107 | uM | 7854.016 | 1.0291 | 1.0642 | 0.9074 | |
| HCC38 | TNBC | Basal B | AG1478 | EGFR | ErbB | 0.0533 | uM | 7854.016 | 0.9986 | 0.9970 | 0.9074 | |
| HCC38 | TNBC | Basal B | AG1478 | EGFR | ErbB | 0.267 | uM | 7854.016 | 1.0560 | 1.1238 | 0.9074 | |
| HCC38 | TNBC | Basal B | AG1478 | EGFR | ErbB | 1.33 | uM | 7854.016 | 0.9582 | 0.9081 | 0.9074 | |
| HCC38 | TNBC | Basal B | AG1478 | EGFR | ErbB | 6.67 | uM | 7854.016 | 1.1067 | 1.2364 | 0.9074 | |
| HCC38 | TNBC | Basal B | AG1478 | EGFR | ErbB | 33.3 | uM | 7854.016 | 0.4395 | -0.1917 | 0.9074 | |
| HCC38 | TNBC | Basal B | AG1478 | EGFR | ErbB | 167 | uM | 7854.016 | 0.6774 | 0.3020 | 0.9074 | |
| HCC38 | TNBC | Basal B | AG1478 | EGFR | ErbB | 0.000427 | uM | 9028.016 | 0.9895 | 0.9830 | 1.2348 | |
| HCC38 | TNBC | Basal B | AG1478 | EGFR | ErbB | 0.00213 | uM | 9028.016 | 0.9706 | 0.9522 | 1.2348 | |
| HCC38 | TNBC | Basal B | AG1478 | EGFR | ErbB | 0.0107 | uM | 9028.016 | 1.0809 | 1.1300 | 1.2348 | |
| HCC38 | TNBC | Basal B | AG1478 | EGFR | ErbB | 0.0533 | uM | 9028.016 | 0.9693 | 0.9501 | 1.2348 | |
| HCC38 | TNBC | Basal B | AG1478 | EGFR | ErbB | 0.267 | uM | 9028.016 | 0.9626 | 0.9393 | 1.2348 | |
| HCC38 | TNBC | Basal B | AG1478 | EGFR | ErbB | 1.33 | uM | 9028.016 | 1.0345 | 1.0556 | 1.2348 | |
| HCC38 | TNBC | Basal B | AG1478 | EGFR | ErbB | 6.67 | uM | 9028.016 | 0.9376 | 0.8982 | 1.2348 | |
| HCC38 | TNBC | Basal B | AG1478 | EGFR | ErbB | 33.3 | uM | 9028.016 | 0.9117 | 0.8557 | 1.2348 | |
| HCC38 | TNBC | Basal B | AG1478 | EGFR | ErbB | 167 | uM | 9028.016 | 0.5158 | 0.1700 | 1.2348 | |
| HCC38 | TNBC | Basal B | AG1478 | EGFR | ErbB | 0.000427 | uM | 9453.019 | 0.9941 | 0.9897 | 1.1486 | |
| HCC38 | TNBC | Basal B | AG1478 | EGFR | ErbB | 0.00213 | uM | 9453.019 | 0.9808 | 0.9665 | 1.1486 | |
| HCC38 | TNBC | Basal B | AG1478 | EGFR | ErbB | 0.0107 | uM | 9453.019 | 0.9794 | 0.9641 | 1.1486 | |
| HCC38 | TNBC | Basal B | AG1478 | EGFR | ErbB | 0.0533 | uM | 9453.019 | 0.9465 | 0.9065 | 1.1486 | |
| HCC38 | TNBC | Basal B | AG1478 | EGFR | ErbB | 0.267 | uM | 9453.019 | 0.9564 | 0.9238 | 1.1486 | |
| HCC38 | TNBC | Basal B | AG1478 | EGFR | ErbB | 1.33 | uM | 9453.019 | 0.9616 | 0.9330 | 1.1486 | |
| HCC38 | TNBC | Basal B | AG1478 | EGFR | ErbB | 6.67 | uM | 9453.019 | 0.9886 | 0.9801 | 1.1486 | |
| HCC38 | TNBC | Basal B | AG1478 | EGFR | ErbB | 33.3 | uM | 9453.019 | 0.9561 | 0.9233 | 1.1486 | |
| HCC38 | TNBC | Basal B | AG1478 | EGFR | ErbB | 167 | uM | 9453.019 | 0.9802 | 0.9654 | 1.1486 |