Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC70 | TNBC | Basal A | AG1478 | EGFR | ErbB | 0.000427 | uM | 7856.016 | 1.0434 | 1.0949 | 0.9156 | |
| HCC70 | TNBC | Basal A | AG1478 | EGFR | ErbB | 0.00213 | uM | 7856.016 | 0.9709 | 0.9364 | 0.9156 | |
| HCC70 | TNBC | Basal A | AG1478 | EGFR | ErbB | 0.0107 | uM | 7856.016 | 1.0518 | 1.1133 | 0.9156 | |
| HCC70 | TNBC | Basal A | AG1478 | EGFR | ErbB | 0.0533 | uM | 7856.016 | 0.9470 | 0.8846 | 0.9156 | |
| HCC70 | TNBC | Basal A | AG1478 | EGFR | ErbB | 0.267 | uM | 7856.016 | 0.9650 | 0.9236 | 0.9156 | |
| HCC70 | TNBC | Basal A | AG1478 | EGFR | ErbB | 1.33 | uM | 7856.016 | 0.9300 | 0.8476 | 0.9156 | |
| HCC70 | TNBC | Basal A | AG1478 | EGFR | ErbB | 6.67 | uM | 7856.016 | 0.9035 | 0.7901 | 0.9156 | |
| HCC70 | TNBC | Basal A | AG1478 | EGFR | ErbB | 33.3 | uM | 7856.016 | 0.9072 | 0.7983 | 0.9156 | |
| HCC70 | TNBC | Basal A | AG1478 | EGFR | ErbB | 167 | uM | 7856.016 | 0.2726 | -0.5164 | 0.9156 | |
| HCC70 | TNBC | Basal A | AG1478 | EGFR | ErbB | 0.000427 | uM | 7857.016 | 0.9875 | 0.9793 | 1.2049 | |
| HCC70 | TNBC | Basal A | AG1478 | EGFR | ErbB | 0.00213 | uM | 7857.016 | 0.9558 | 0.9263 | 1.2049 | |
| HCC70 | TNBC | Basal A | AG1478 | EGFR | ErbB | 0.0107 | uM | 7857.016 | 0.9554 | 0.9257 | 1.2049 | |
| HCC70 | TNBC | Basal A | AG1478 | EGFR | ErbB | 0.0533 | uM | 7857.016 | 0.9592 | 0.9320 | 1.2049 | |
| HCC70 | TNBC | Basal A | AG1478 | EGFR | ErbB | 0.267 | uM | 7857.016 | 0.9378 | 0.8961 | 1.2049 | |
| HCC70 | TNBC | Basal A | AG1478 | EGFR | ErbB | 1.33 | uM | 7857.016 | 0.8658 | 0.7746 | 1.2049 | |
| HCC70 | TNBC | Basal A | AG1478 | EGFR | ErbB | 6.67 | uM | 7857.016 | 0.7757 | 0.6199 | 1.2049 | |
| HCC70 | TNBC | Basal A | AG1478 | EGFR | ErbB | 33.3 | uM | 7857.016 | 0.8825 | 0.8029 | 1.2049 | |
| HCC70 | TNBC | Basal A | AG1478 | EGFR | ErbB | 167 | uM | 7857.016 | 0.8074 | 0.6747 | 1.2049 | |
| HCC70 | TNBC | Basal A | AG1478 | EGFR | ErbB | 0.000427 | uM | 7860.016 | 1.0545 | 1.1804 | 0.6145 | |
| HCC70 | TNBC | Basal A | AG1478 | EGFR | ErbB | 0.00213 | uM | 7860.016 | 0.9851 | 0.9516 | 0.6145 | |
| HCC70 | TNBC | Basal A | AG1478 | EGFR | ErbB | 0.0107 | uM | 7860.016 | 1.0523 | 1.1729 | 0.6145 | |
| HCC70 | TNBC | Basal A | AG1478 | EGFR | ErbB | 0.0533 | uM | 7860.016 | 0.9913 | 0.9717 | 0.6145 | |
| HCC70 | TNBC | Basal A | AG1478 | EGFR | ErbB | 0.267 | uM | 7860.016 | 0.9887 | 0.9632 | 0.6145 | |
| HCC70 | TNBC | Basal A | AG1478 | EGFR | ErbB | 1.33 | uM | 7860.016 | 0.8969 | 0.6755 | 0.6145 | |
| HCC70 | TNBC | Basal A | AG1478 | EGFR | ErbB | 6.67 | uM | 7860.016 | 0.7646 | 0.2921 | 0.6145 |