Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1395 | TNBC | Basal B | AG1478 | EGFR | ErbB | 0.0107 | uM | 7814.016 | 0.9888 | 0.9740 | 0.8623 | |
| HCC1395 | TNBC | Basal B | AG1478 | EGFR | ErbB | 0.0533 | uM | 7814.016 | 0.9851 | 0.9655 | 0.8623 | |
| HCC1395 | TNBC | Basal B | AG1478 | EGFR | ErbB | 0.267 | uM | 7814.016 | 0.9346 | 0.8490 | 0.8623 | |
| HCC1395 | TNBC | Basal B | AG1478 | EGFR | ErbB | 1.33 | uM | 7814.016 | 0.9855 | 0.9663 | 0.8623 | |
| HCC1395 | TNBC | Basal B | AG1478 | EGFR | ErbB | 6.67 | uM | 7814.016 | 0.9231 | 0.8227 | 0.8623 | |
| HCC1395 | TNBC | Basal B | AG1478 | EGFR | ErbB | 33.3 | uM | 7814.016 | 0.6777 | 0.2739 | 0.8623 | |
| HCC1395 | TNBC | Basal B | AG1478 | EGFR | ErbB | 167 | uM | 7814.016 | 0.1520 | -0.7749 | 0.8623 | |
| HCC1395 | TNBC | Basal B | AG1478 | EGFR | ErbB | 0.000427 | uM | 7815.016 | 1.0186 | 1.0863 | 0.4370 | |
| HCC1395 | TNBC | Basal B | AG1478 | EGFR | ErbB | 0.00213 | uM | 7815.016 | 1.0127 | 1.0587 | 0.4370 | |
| HCC1395 | TNBC | Basal B | AG1478 | EGFR | ErbB | 0.0107 | uM | 7815.016 | 1.0292 | 1.1361 | 0.4370 | |
| HCC1395 | TNBC | Basal B | AG1478 | EGFR | ErbB | 0.0533 | uM | 7815.016 | 1.0064 | 1.0292 | 0.4370 | |
| HCC1395 | TNBC | Basal B | AG1478 | EGFR | ErbB | 0.267 | uM | 7815.016 | 1.0564 | 1.2678 | 0.4370 | |
| HCC1395 | TNBC | Basal B | AG1478 | EGFR | ErbB | 1.33 | uM | 7815.016 | 1.0015 | 1.0069 | 0.4370 | |
| HCC1395 | TNBC | Basal B | AG1478 | EGFR | ErbB | 6.67 | uM | 7815.016 | 1.0230 | 1.1067 | 0.4370 | |
| HCC1395 | TNBC | Basal B | AG1478 | EGFR | ErbB | 33.3 | uM | 7815.016 | 0.8143 | 0.2498 | 0.4370 | |
| HCC1395 | TNBC | Basal B | AG1478 | EGFR | ErbB | 167 | uM | 7815.016 | 1.0118 | 1.0542 | 0.4370 | |
| HCC1395 | TNBC | Basal B | AG1478 | EGFR | ErbB | 0.000427 | uM | 7816.016 | 0.9391 | 0.8907 | 1.1183 | |
| HCC1395 | TNBC | Basal B | AG1478 | EGFR | ErbB | 0.00213 | uM | 7816.016 | 0.9206 | 0.8574 | 1.1183 | |
| HCC1395 | TNBC | Basal B | AG1478 | EGFR | ErbB | 0.0107 | uM | 7816.016 | 0.9741 | 0.9537 | 1.1183 | |
| HCC1395 | TNBC | Basal B | AG1478 | EGFR | ErbB | 0.0533 | uM | 7816.016 | 0.9273 | 0.8694 | 1.1183 | |
| HCC1395 | TNBC | Basal B | AG1478 | EGFR | ErbB | 0.267 | uM | 7816.016 | 0.9106 | 0.8394 | 1.1183 | |
| HCC1395 | TNBC | Basal B | AG1478 | EGFR | ErbB | 1.33 | uM | 7816.016 | 0.9093 | 0.8371 | 1.1183 | |
| HCC1395 | TNBC | Basal B | AG1478 | EGFR | ErbB | 6.67 | uM | 7816.016 | 0.9057 | 0.8304 | 1.1183 | |
| HCC1395 | TNBC | Basal B | AG1478 | EGFR | ErbB | 33.3 | uM | 7816.016 | 0.9816 | 0.9671 | 1.1183 | |
| HCC1395 | TNBC | Basal B | AG1478 | EGFR | ErbB | 167 | uM | 7816.016 | 0.6925 | 0.4398 | 1.1183 |