Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| T47D | HR+ | Luminal | AG1024 | IGF1R | RTK | 0.0533 | uM | 7542.066 | 0.9756 | 0.9547 | 1.0766 | |
| T47D | HR+ | Luminal | AG1024 | IGF1R | RTK | 0.267 | uM | 7542.066 | 0.9291 | 0.8679 | 1.0766 | |
| T47D | HR+ | Luminal | AG1024 | IGF1R | RTK | 1.33 | uM | 7542.066 | 0.9417 | 0.8915 | 1.0766 | |
| T47D | HR+ | Luminal | AG1024 | IGF1R | RTK | 6.67 | uM | 7542.066 | 0.8625 | 0.7432 | 1.0766 | |
| T47D | HR+ | Luminal | AG1024 | IGF1R | RTK | 33.3 | uM | 7542.066 | 0.7669 | 0.5631 | 1.0766 | |
| T47D | HR+ | Luminal | AG1024 | IGF1R | RTK | 0.0000853 | uM | 7543.066 | 0.9808 | 0.9742 | 1.4960 | |
| T47D | HR+ | Luminal | AG1024 | IGF1R | RTK | 0.000427 | uM | 7543.066 | 0.9600 | 0.9461 | 1.4960 | |
| T47D | HR+ | Luminal | AG1024 | IGF1R | RTK | 0.00213 | uM | 7543.066 | 0.9962 | 0.9950 | 1.4960 | |
| T47D | HR+ | Luminal | AG1024 | IGF1R | RTK | 0.0107 | uM | 7543.066 | 1.0280 | 1.0372 | 1.4960 | |
| T47D | HR+ | Luminal | AG1024 | IGF1R | RTK | 0.0533 | uM | 7543.066 | 0.9561 | 0.9408 | 1.4960 | |
| T47D | HR+ | Luminal | AG1024 | IGF1R | RTK | 0.267 | uM | 7543.066 | 0.9201 | 0.8916 | 1.4960 | |
| T47D | HR+ | Luminal | AG1024 | IGF1R | RTK | 1.33 | uM | 7543.066 | 1.0046 | 1.0061 | 1.4960 | |
| T47D | HR+ | Luminal | AG1024 | IGF1R | RTK | 6.67 | uM | 7543.066 | 0.8492 | 0.7930 | 1.4960 | |
| T47D | HR+ | Luminal | AG1024 | IGF1R | RTK | 33.3 | uM | 7543.066 | 0.5832 | 0.3948 | 1.4960 | |
| T47DKBLUC | Unknown | Unknown | AG1024 | IGF1R | RTK | 0.0000853 | uM | 7544.066 | 1.0052 | 1.0095 | 1.0898 | |
| T47DKBLUC | Unknown | Unknown | AG1024 | IGF1R | RTK | 0.000427 | uM | 7544.066 | 0.9491 | 0.9064 | 1.0898 | |
| T47DKBLUC | Unknown | Unknown | AG1024 | IGF1R | RTK | 0.00213 | uM | 7544.066 | 1.0322 | 1.0590 | 1.0898 | |
| T47DKBLUC | Unknown | Unknown | AG1024 | IGF1R | RTK | 0.0107 | uM | 7544.066 | 0.9591 | 0.9249 | 1.0898 | |
| T47DKBLUC | Unknown | Unknown | AG1024 | IGF1R | RTK | 0.0533 | uM | 7544.066 | 0.9547 | 0.9167 | 1.0898 | |
| T47DKBLUC | Unknown | Unknown | AG1024 | IGF1R | RTK | 0.267 | uM | 7544.066 | 0.9930 | 0.9872 | 1.0898 | |
| T47DKBLUC | Unknown | Unknown | AG1024 | IGF1R | RTK | 1.33 | uM | 7544.066 | 0.9892 | 0.9803 | 1.0898 | |
| T47DKBLUC | Unknown | Unknown | AG1024 | IGF1R | RTK | 6.67 | uM | 7544.066 | 0.9696 | 0.9441 | 1.0898 | |
| T47DKBLUC | Unknown | Unknown | AG1024 | IGF1R | RTK | 33.3 | uM | 7544.066 | 0.8408 | 0.7057 | 1.0898 | |
| T47DKBLUC | Unknown | Unknown | AG1024 | IGF1R | RTK | 0.0000853 | uM | 7545.066 | 1.0034 | 1.0053 | 1.2546 | |
| T47DKBLUC | Unknown | Unknown | AG1024 | IGF1R | RTK | 0.000427 | uM | 7545.066 | 0.9101 | 0.8554 | 1.2546 |