Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| T47DKBLUC | Unknown | Unknown | AG1024 | IGF1R | RTK | 0.00213 | uM | 7545.066 | 0.9070 | 0.8503 | 1.2546 | |
| T47DKBLUC | Unknown | Unknown | AG1024 | IGF1R | RTK | 0.0107 | uM | 7545.066 | 1.0052 | 1.0083 | 1.2546 | |
| T47DKBLUC | Unknown | Unknown | AG1024 | IGF1R | RTK | 0.0533 | uM | 7545.066 | 1.0301 | 1.0479 | 1.2546 | |
| T47DKBLUC | Unknown | Unknown | AG1024 | IGF1R | RTK | 0.267 | uM | 7545.066 | 0.9280 | 0.8844 | 1.2546 | |
| T47DKBLUC | Unknown | Unknown | AG1024 | IGF1R | RTK | 1.33 | uM | 7545.066 | 0.9855 | 0.9768 | 1.2546 | |
| T47DKBLUC | Unknown | Unknown | AG1024 | IGF1R | RTK | 6.67 | uM | 7545.066 | 0.8611 | 0.7753 | 1.2546 | |
| T47DKBLUC | Unknown | Unknown | AG1024 | IGF1R | RTK | 33.3 | uM | 7545.066 | 0.7620 | 0.6104 | 1.2546 | |
| T47DKBLUC | Unknown | Unknown | AG1024 | IGF1R | RTK | 0.0000853 | uM | 7546.066 | 1.0264 | 1.0603 | 0.8758 | |
| T47DKBLUC | Unknown | Unknown | AG1024 | IGF1R | RTK | 0.000427 | uM | 7546.066 | 1.0259 | 1.0593 | 0.8758 | |
| T47DKBLUC | Unknown | Unknown | AG1024 | IGF1R | RTK | 0.00213 | uM | 7546.066 | 1.0261 | 1.0598 | 0.8758 | |
| T47DKBLUC | Unknown | Unknown | AG1024 | IGF1R | RTK | 0.0107 | uM | 7546.066 | 1.0466 | 1.1067 | 0.8758 | |
| T47DKBLUC | Unknown | Unknown | AG1024 | IGF1R | RTK | 0.0533 | uM | 7546.066 | 1.0434 | 1.0994 | 0.8758 | |
| T47DKBLUC | Unknown | Unknown | AG1024 | IGF1R | RTK | 0.267 | uM | 7546.066 | 0.9975 | 0.9944 | 0.8758 | |
| T47DKBLUC | Unknown | Unknown | AG1024 | IGF1R | RTK | 1.33 | uM | 7546.066 | 0.9995 | 0.9988 | 0.8758 | |
| T47DKBLUC | Unknown | Unknown | AG1024 | IGF1R | RTK | 6.67 | uM | 7546.066 | 0.9417 | 0.8674 | 0.8758 | |
| T47DKBLUC | Unknown | Unknown | AG1024 | IGF1R | RTK | 33.3 | uM | 7546.066 | 0.4341 | -0.2287 | 0.8758 | |
| UACC-812 | HER2amp | Luminal | AG1024 | IGF1R | RTK | 0.0000853 | uM | 7547.066 | 0.9081 | 0.8062 | 0.9460 | |
| UACC-812 | HER2amp | Luminal | AG1024 | IGF1R | RTK | 0.000427 | uM | 7547.066 | 0.7658 | 0.5083 | 0.9460 | |
| UACC-812 | HER2amp | Luminal | AG1024 | IGF1R | RTK | 0.00213 | uM | 7547.066 | 0.9026 | 0.7948 | 0.9460 | |
| UACC-812 | HER2amp | Luminal | AG1024 | IGF1R | RTK | 0.0107 | uM | 7547.066 | 0.8738 | 0.7342 | 0.9460 | |
| UACC-812 | HER2amp | Luminal | AG1024 | IGF1R | RTK | 0.0533 | uM | 7547.066 | 0.8794 | 0.7459 | 0.9460 | |
| UACC-812 | HER2amp | Luminal | AG1024 | IGF1R | RTK | 0.267 | uM | 7547.066 | 0.8801 | 0.7475 | 0.9460 | |
| UACC-812 | HER2amp | Luminal | AG1024 | IGF1R | RTK | 1.33 | uM | 7547.066 | 0.9154 | 0.8215 | 0.9460 | |
| UACC-812 | HER2amp | Luminal | AG1024 | IGF1R | RTK | 6.67 | uM | 7547.066 | 0.8246 | 0.6311 | 0.9460 | |
| UACC-812 | HER2amp | Luminal | AG1024 | IGF1R | RTK | 33.3 | uM | 7547.066 | 0.7617 | 0.4999 | 0.9460 |