Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
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MDA-MB-361 | HER2amp | Luminal | AG1024 | IGF1R | RTK | 0.0533 | uM | 7507.066 | 0.9444 | 0.8784 | 0.9124 | |
MDA-MB-361 | HER2amp | Luminal | AG1024 | IGF1R | RTK | 0.267 | uM | 7507.066 | 0.9752 | 0.9457 | 0.9124 | |
MDA-MB-361 | HER2amp | Luminal | AG1024 | IGF1R | RTK | 1.33 | uM | 7507.066 | 0.9127 | 0.8094 | 0.9124 | |
MDA-MB-361 | HER2amp | Luminal | AG1024 | IGF1R | RTK | 6.67 | uM | 7507.066 | 0.9153 | 0.8151 | 0.9124 | |
MDA-MB-361 | HER2amp | Luminal | AG1024 | IGF1R | RTK | 33.3 | uM | 7507.066 | 0.6635 | 0.2758 | 0.9124 | |
MDA-MB-361 | HER2amp | Luminal | AG1024 | IGF1R | RTK | 0.0000853 | uM | 7508.066 | 0.9542 | 0.8982 | 0.8980 | |
MDA-MB-361 | HER2amp | Luminal | AG1024 | IGF1R | RTK | 0.000427 | uM | 7508.066 | 0.9797 | 0.9548 | 0.8980 | |
MDA-MB-361 | HER2amp | Luminal | AG1024 | IGF1R | RTK | 0.00213 | uM | 7508.066 | 0.9966 | 0.9923 | 0.8980 | |
MDA-MB-361 | HER2amp | Luminal | AG1024 | IGF1R | RTK | 0.0107 | uM | 7508.066 | 0.9591 | 0.9092 | 0.8980 | |
MDA-MB-361 | HER2amp | Luminal | AG1024 | IGF1R | RTK | 0.0533 | uM | 7508.066 | 0.9421 | 0.8716 | 0.8980 | |
MDA-MB-361 | HER2amp | Luminal | AG1024 | IGF1R | RTK | 0.267 | uM | 7508.066 | 0.9326 | 0.8506 | 0.8980 | |
MDA-MB-361 | HER2amp | Luminal | AG1024 | IGF1R | RTK | 1.33 | uM | 7508.066 | 0.9083 | 0.7970 | 0.8980 | |
MDA-MB-361 | HER2amp | Luminal | AG1024 | IGF1R | RTK | 6.67 | uM | 7508.066 | 0.9606 | 0.9124 | 0.8980 | |
MDA-MB-361 | HER2amp | Luminal | AG1024 | IGF1R | RTK | 33.3 | uM | 7508.066 | 1.0015 | 1.0033 | 0.8980 | |
MDA-MB-361 | HER2amp | Luminal | AG1024 | IGF1R | RTK | 0.0000853 | uM | 10472.066 | 1.0215 | 1.0584 | 0.7390 | |
MDA-MB-361 | HER2amp | Luminal | AG1024 | IGF1R | RTK | 0.000427 | uM | 10472.066 | 0.9799 | 0.9458 | 0.7390 | |
MDA-MB-361 | HER2amp | Luminal | AG1024 | IGF1R | RTK | 0.00213 | uM | 10472.066 | 1.0470 | 1.1282 | 0.7390 | |
MDA-MB-361 | HER2amp | Luminal | AG1024 | IGF1R | RTK | 0.0107 | uM | 10472.066 | 0.9896 | 0.9718 | 0.7390 | |
MDA-MB-361 | HER2amp | Luminal | AG1024 | IGF1R | RTK | 0.0533 | uM | 10472.066 | 0.9902 | 0.9736 | 0.7390 | |
MDA-MB-361 | HER2amp | Luminal | AG1024 | IGF1R | RTK | 0.267 | uM | 10472.066 | 1.0039 | 1.0105 | 0.7390 | |
MDA-MB-361 | HER2amp | Luminal | AG1024 | IGF1R | RTK | 1.33 | uM | 10472.066 | 1.0316 | 1.0860 | 0.7390 | |
MDA-MB-361 | HER2amp | Luminal | AG1024 | IGF1R | RTK | 6.67 | uM | 10472.066 | 0.9902 | 0.9736 | 0.7390 | |
MDA-MB-361 | HER2amp | Luminal | AG1024 | IGF1R | RTK | 33.3 | uM | 10472.066 | 0.9833 | 0.9550 | 0.7390 | |
MDA-MB-415 | HR+ | Luminal | AG1024 | IGF1R | RTK | 0.0000853 | uM | 7510.066 | 0.9123 | 0.8099 | 0.9189 | |
MDA-MB-415 | HR+ | Luminal | AG1024 | IGF1R | RTK | 0.000427 | uM | 7510.066 | 0.9762 | 0.9483 | 0.9189 |