Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MDA-MB-415 | HR+ | Luminal | AG1024 | IGF1R | RTK | 0.00213 | uM | 7510.066 | 0.9402 | 0.8703 | 0.9189 | |
| MDA-MB-415 | HR+ | Luminal | AG1024 | IGF1R | RTK | 0.0107 | uM | 7510.066 | 0.9687 | 0.9319 | 0.9189 | |
| MDA-MB-415 | HR+ | Luminal | AG1024 | IGF1R | RTK | 0.0533 | uM | 7510.066 | 0.9120 | 0.8092 | 0.9189 | |
| MDA-MB-415 | HR+ | Luminal | AG1024 | IGF1R | RTK | 0.267 | uM | 7510.066 | 0.9003 | 0.7839 | 0.9189 | |
| MDA-MB-415 | HR+ | Luminal | AG1024 | IGF1R | RTK | 1.33 | uM | 7510.066 | 0.8879 | 0.7572 | 0.9189 | |
| MDA-MB-415 | HR+ | Luminal | AG1024 | IGF1R | RTK | 6.67 | uM | 7510.066 | 0.9897 | 0.9775 | 0.9189 | |
| MDA-MB-415 | HR+ | Luminal | AG1024 | IGF1R | RTK | 33.3 | uM | 7510.066 | 0.8689 | 0.7164 | 0.9189 | |
| MDA-MB-415 | HR+ | Luminal | AG1024 | IGF1R | RTK | 0.0000853 | uM | 7511.066 | 1.0446 | 1.0761 | 1.1691 | |
| MDA-MB-415 | HR+ | Luminal | AG1024 | IGF1R | RTK | 0.000427 | uM | 7511.066 | 0.9845 | 0.9734 | 1.1691 | |
| MDA-MB-415 | HR+ | Luminal | AG1024 | IGF1R | RTK | 0.00213 | uM | 7511.066 | 1.0244 | 1.0417 | 1.1691 | |
| MDA-MB-415 | HR+ | Luminal | AG1024 | IGF1R | RTK | 0.0107 | uM | 7511.066 | 1.0049 | 1.0084 | 1.1691 | |
| MDA-MB-415 | HR+ | Luminal | AG1024 | IGF1R | RTK | 0.0533 | uM | 7511.066 | 1.0261 | 1.0445 | 1.1691 | |
| MDA-MB-415 | HR+ | Luminal | AG1024 | IGF1R | RTK | 0.267 | uM | 7511.066 | 0.9926 | 0.9873 | 1.1691 | |
| MDA-MB-415 | HR+ | Luminal | AG1024 | IGF1R | RTK | 1.33 | uM | 7511.066 | 1.0404 | 1.0689 | 1.1691 | |
| MDA-MB-415 | HR+ | Luminal | AG1024 | IGF1R | RTK | 6.67 | uM | 7511.066 | 1.0313 | 1.0534 | 1.1691 | |
| MDA-MB-415 | HR+ | Luminal | AG1024 | IGF1R | RTK | 33.3 | uM | 7511.066 | 0.9878 | 0.9792 | 1.1691 | |
| MDA-MB-415 | HR+ | Luminal | AG1024 | IGF1R | RTK | 0.0000853 | uM | 7512.066 | 1.0306 | 1.0710 | 0.8629 | |
| MDA-MB-415 | HR+ | Luminal | AG1024 | IGF1R | RTK | 0.000427 | uM | 7512.066 | 1.0590 | 1.1373 | 0.8629 | |
| MDA-MB-415 | HR+ | Luminal | AG1024 | IGF1R | RTK | 0.00213 | uM | 7512.066 | 1.0111 | 1.0257 | 0.8629 | |
| MDA-MB-415 | HR+ | Luminal | AG1024 | IGF1R | RTK | 0.0107 | uM | 7512.066 | 1.0471 | 1.1097 | 0.8629 | |
| MDA-MB-415 | HR+ | Luminal | AG1024 | IGF1R | RTK | 0.0533 | uM | 7512.066 | 0.9658 | 0.9209 | 0.8629 | |
| MDA-MB-415 | HR+ | Luminal | AG1024 | IGF1R | RTK | 0.267 | uM | 7512.066 | 1.0040 | 1.0092 | 0.8629 | |
| MDA-MB-415 | HR+ | Luminal | AG1024 | IGF1R | RTK | 1.33 | uM | 7512.066 | 0.9878 | 0.9718 | 0.8629 | |
| MDA-MB-415 | HR+ | Luminal | AG1024 | IGF1R | RTK | 6.67 | uM | 7512.066 | 0.9887 | 0.9738 | 0.8629 | |
| MDA-MB-415 | HR+ | Luminal | AG1024 | IGF1R | RTK | 33.3 | uM | 7512.066 | 1.0932 | 1.2176 | 0.8629 |