Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC38 | TNBC | Basal B | AG1024 | IGF1R | RTK | 1.33 | uM | 10418.066 | 0.9778 | 0.9614 | 1.1532 | |
| HCC38 | TNBC | Basal B | AG1024 | IGF1R | RTK | 6.67 | uM | 10418.066 | 0.9697 | 0.9474 | 1.1532 | |
| HCC38 | TNBC | Basal B | AG1024 | IGF1R | RTK | 33.3 | uM | 10418.066 | 0.9448 | 0.9039 | 1.1532 | |
| HCC70 | TNBC | Basal A | AG1024 | IGF1R | RTK | 0.0000853 | uM | 7470.066 | 0.9602 | 0.9260 | 1.0766 | |
| HCC70 | TNBC | Basal A | AG1024 | IGF1R | RTK | 0.000427 | uM | 7470.066 | 0.9412 | 0.8905 | 1.0766 | |
| HCC70 | TNBC | Basal A | AG1024 | IGF1R | RTK | 0.00213 | uM | 7470.066 | 0.9089 | 0.8303 | 1.0766 | |
| HCC70 | TNBC | Basal A | AG1024 | IGF1R | RTK | 0.0107 | uM | 7470.066 | 0.9635 | 0.9321 | 1.0766 | |
| HCC70 | TNBC | Basal A | AG1024 | IGF1R | RTK | 0.0533 | uM | 7470.066 | 1.0006 | 1.0011 | 1.0766 | |
| HCC70 | TNBC | Basal A | AG1024 | IGF1R | RTK | 0.267 | uM | 7470.066 | 0.9442 | 0.8961 | 1.0766 | |
| HCC70 | TNBC | Basal A | AG1024 | IGF1R | RTK | 1.33 | uM | 7470.066 | 0.9806 | 0.9640 | 1.0766 | |
| HCC70 | TNBC | Basal A | AG1024 | IGF1R | RTK | 6.67 | uM | 7470.066 | 0.6665 | 0.3719 | 1.0766 | |
| HCC70 | TNBC | Basal A | AG1024 | IGF1R | RTK | 33.3 | uM | 7470.066 | 0.5261 | 0.1014 | 1.0766 | |
| Hs 578T | TNBC | Basal B | AG1024 | IGF1R | RTK | 0.0000853 | uM | 7471.066 | 1.0389 | 1.0337 | 2.2865 | |
| Hs 578T | TNBC | Basal B | AG1024 | IGF1R | RTK | 0.000427 | uM | 7471.066 | 0.9645 | 0.9687 | 2.2865 | |
| Hs 578T | TNBC | Basal B | AG1024 | IGF1R | RTK | 0.00213 | uM | 7471.066 | 0.9756 | 0.9785 | 2.2865 | |
| Hs 578T | TNBC | Basal B | AG1024 | IGF1R | RTK | 0.0107 | uM | 7471.066 | 1.0263 | 1.0228 | 2.2865 | |
| Hs 578T | TNBC | Basal B | AG1024 | IGF1R | RTK | 0.0533 | uM | 7471.066 | 1.0562 | 1.0484 | 2.2865 | |
| Hs 578T | TNBC | Basal B | AG1024 | IGF1R | RTK | 0.267 | uM | 7471.066 | 0.9736 | 0.9767 | 2.2865 | |
| Hs 578T | TNBC | Basal B | AG1024 | IGF1R | RTK | 1.33 | uM | 7471.066 | 0.9649 | 0.9690 | 2.2865 | |
| Hs 578T | TNBC | Basal B | AG1024 | IGF1R | RTK | 6.67 | uM | 7471.066 | 0.9854 | 0.9872 | 2.2865 | |
| Hs 578T | TNBC | Basal B | AG1024 | IGF1R | RTK | 33.3 | uM | 7471.066 | 0.9544 | 0.9596 | 2.2865 | |
| Hs 578T | TNBC | Basal B | AG1024 | IGF1R | RTK | 0.0000853 | uM | 7472.066 | 1.1616 | 1.1700 | 1.8363 | |
| Hs 578T | TNBC | Basal B | AG1024 | IGF1R | RTK | 0.000427 | uM | 7472.066 | 1.0357 | 1.0386 | 1.8363 | |
| Hs 578T | TNBC | Basal B | AG1024 | IGF1R | RTK | 0.00213 | uM | 7472.066 | 1.0179 | 1.0194 | 1.8363 | |
| Hs 578T | TNBC | Basal B | AG1024 | IGF1R | RTK | 0.0107 | uM | 7472.066 | 0.9899 | 0.9890 | 1.8363 |