Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC3153 | TNBC | Basal A | AG1024 | IGF1R | RTK | 33.3 | uM | 7467.066 | 0.5516 | 0.2160 | 1.1956 | |
| HCC38 | TNBC | Basal B | AG1024 | IGF1R | RTK | 0.0000853 | uM | 7468.066 | 0.9782 | 0.9686 | 1.3940 | |
| HCC38 | TNBC | Basal B | AG1024 | IGF1R | RTK | 0.000427 | uM | 7468.066 | 0.9517 | 0.9303 | 1.3940 | |
| HCC38 | TNBC | Basal B | AG1024 | IGF1R | RTK | 0.00213 | uM | 7468.066 | 0.9733 | 0.9616 | 1.3940 | |
| HCC38 | TNBC | Basal B | AG1024 | IGF1R | RTK | 0.0107 | uM | 7468.066 | 0.9488 | 0.9260 | 1.3940 | |
| HCC38 | TNBC | Basal B | AG1024 | IGF1R | RTK | 0.0533 | uM | 7468.066 | 0.9757 | 0.9650 | 1.3940 | |
| HCC38 | TNBC | Basal B | AG1024 | IGF1R | RTK | 0.267 | uM | 7468.066 | 0.9413 | 0.9151 | 1.3940 | |
| HCC38 | TNBC | Basal B | AG1024 | IGF1R | RTK | 1.33 | uM | 7468.066 | 1.0155 | 1.0222 | 1.3940 | |
| HCC38 | TNBC | Basal B | AG1024 | IGF1R | RTK | 6.67 | uM | 7468.066 | 0.9084 | 0.8667 | 1.3940 | |
| HCC38 | TNBC | Basal B | AG1024 | IGF1R | RTK | 33.3 | uM | 7468.066 | 0.8004 | 0.7048 | 1.3940 | |
| HCC38 | TNBC | Basal B | AG1024 | IGF1R | RTK | 0.0000853 | uM | 7469.066 | 0.9636 | 0.9634 | 2.0057 | |
| HCC38 | TNBC | Basal B | AG1024 | IGF1R | RTK | 0.000427 | uM | 7469.066 | 0.9564 | 0.9560 | 2.0057 | |
| HCC38 | TNBC | Basal B | AG1024 | IGF1R | RTK | 0.00213 | uM | 7469.066 | 1.0059 | 1.0059 | 2.0057 | |
| HCC38 | TNBC | Basal B | AG1024 | IGF1R | RTK | 0.0107 | uM | 7469.066 | 1.0037 | 1.0037 | 2.0057 | |
| HCC38 | TNBC | Basal B | AG1024 | IGF1R | RTK | 0.0533 | uM | 7469.066 | 0.9709 | 0.9708 | 2.0057 | |
| HCC38 | TNBC | Basal B | AG1024 | IGF1R | RTK | 0.267 | uM | 7469.066 | 0.9787 | 0.9786 | 2.0057 | |
| HCC38 | TNBC | Basal B | AG1024 | IGF1R | RTK | 1.33 | uM | 7469.066 | 1.0173 | 1.0172 | 2.0057 | |
| HCC38 | TNBC | Basal B | AG1024 | IGF1R | RTK | 6.67 | uM | 7469.066 | 0.9972 | 0.9972 | 2.0057 | |
| HCC38 | TNBC | Basal B | AG1024 | IGF1R | RTK | 33.3 | uM | 7469.066 | 0.9728 | 0.9727 | 2.0057 | |
| HCC38 | TNBC | Basal B | AG1024 | IGF1R | RTK | 0.0000853 | uM | 10418.066 | 1.0341 | 1.0589 | 1.1532 | |
| HCC38 | TNBC | Basal B | AG1024 | IGF1R | RTK | 0.000427 | uM | 10418.066 | 0.9347 | 0.8863 | 1.1532 | |
| HCC38 | TNBC | Basal B | AG1024 | IGF1R | RTK | 0.00213 | uM | 10418.066 | 0.9497 | 0.9124 | 1.1532 | |
| HCC38 | TNBC | Basal B | AG1024 | IGF1R | RTK | 0.0107 | uM | 10418.066 | 0.9581 | 0.9272 | 1.1532 | |
| HCC38 | TNBC | Basal B | AG1024 | IGF1R | RTK | 0.0533 | uM | 10418.066 | 1.0052 | 1.0091 | 1.1532 | |
| HCC38 | TNBC | Basal B | AG1024 | IGF1R | RTK | 0.267 | uM | 10418.066 | 0.9380 | 0.8919 | 1.1532 |