Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1428 | HR+ | Luminal | AG1024 | IGF1R | RTK | 33.3 | uM | 7441.066 | 0.7739 | 0.4270 | 0.7593 | |
| HCC1428 | HR+ | Luminal | AG1024 | IGF1R | RTK | 0.0000853 | uM | 7442.066 | 0.9981 | 0.9955 | 0.8481 | |
| HCC1428 | HR+ | Luminal | AG1024 | IGF1R | RTK | 0.000427 | uM | 7442.066 | 0.9691 | 0.9272 | 0.8481 | |
| HCC1428 | HR+ | Luminal | AG1024 | IGF1R | RTK | 0.00213 | uM | 7442.066 | 0.9862 | 0.9676 | 0.8481 | |
| HCC1428 | HR+ | Luminal | AG1024 | IGF1R | RTK | 0.0107 | uM | 7442.066 | 0.9885 | 0.9730 | 0.8481 | |
| HCC1428 | HR+ | Luminal | AG1024 | IGF1R | RTK | 0.0533 | uM | 7442.066 | 0.9935 | 0.9848 | 0.8481 | |
| HCC1428 | HR+ | Luminal | AG1024 | IGF1R | RTK | 0.267 | uM | 7442.066 | 0.9363 | 0.8507 | 0.8481 | |
| HCC1428 | HR+ | Luminal | AG1024 | IGF1R | RTK | 1.33 | uM | 7442.066 | 0.9792 | 0.9511 | 0.8481 | |
| HCC1428 | HR+ | Luminal | AG1024 | IGF1R | RTK | 6.67 | uM | 7442.066 | 0.8362 | 0.6197 | 0.8481 | |
| HCC1428 | HR+ | Luminal | AG1024 | IGF1R | RTK | 33.3 | uM | 7442.066 | 0.7204 | 0.3585 | 0.8481 | |
| HCC1428 | HR+ | Luminal | AG1024 | IGF1R | RTK | 0.0000853 | uM | 7443.066 | 0.9924 | 0.9840 | 0.9414 | |
| HCC1428 | HR+ | Luminal | AG1024 | IGF1R | RTK | 0.000427 | uM | 7443.066 | 0.9940 | 0.9872 | 0.9414 | |
| HCC1428 | HR+ | Luminal | AG1024 | IGF1R | RTK | 0.00213 | uM | 7443.066 | 0.9795 | 0.9564 | 0.9414 | |
| HCC1428 | HR+ | Luminal | AG1024 | IGF1R | RTK | 0.0107 | uM | 7443.066 | 1.0221 | 1.0471 | 0.9414 | |
| HCC1428 | HR+ | Luminal | AG1024 | IGF1R | RTK | 0.0533 | uM | 7443.066 | 1.0172 | 1.0365 | 0.9414 | |
| HCC1428 | HR+ | Luminal | AG1024 | IGF1R | RTK | 0.267 | uM | 7443.066 | 0.9583 | 0.9115 | 0.9414 | |
| HCC1428 | HR+ | Luminal | AG1024 | IGF1R | RTK | 1.33 | uM | 7443.066 | 0.9781 | 0.9536 | 0.9414 | |
| HCC1428 | HR+ | Luminal | AG1024 | IGF1R | RTK | 6.67 | uM | 7443.066 | 0.8014 | 0.5809 | 0.9414 | |
| HCC1428 | HR+ | Luminal | AG1024 | IGF1R | RTK | 33.3 | uM | 7443.066 | 0.6996 | 0.3685 | 0.9414 | |
| HCC1428 | HR+ | Luminal | AG1024 | IGF1R | RTK | 0.0000853 | uM | 7444.066 | 0.9963 | 0.9894 | 0.6972 | |
| HCC1428 | HR+ | Luminal | AG1024 | IGF1R | RTK | 0.000427 | uM | 7444.066 | 1.0583 | 1.1692 | 0.6972 | |
| HCC1428 | HR+ | Luminal | AG1024 | IGF1R | RTK | 0.00213 | uM | 7444.066 | 1.0119 | 1.0341 | 0.6972 | |
| HCC1428 | HR+ | Luminal | AG1024 | IGF1R | RTK | 0.0107 | uM | 7444.066 | 0.9946 | 0.9846 | 0.6972 | |
| HCC1428 | HR+ | Luminal | AG1024 | IGF1R | RTK | 0.0533 | uM | 7444.066 | 0.9978 | 0.9938 | 0.6972 | |
| HCC1428 | HR+ | Luminal | AG1024 | IGF1R | RTK | 0.267 | uM | 7444.066 | 1.0783 | 1.2284 | 0.6972 |